There are 6 ways to get from Pisa to Palermo by plane, train, ferry, bus, train (Trenitalia), or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
2h 22m€44–201Train, ferry via Messina
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Florence Santa Maria Novella to Villa San Giovannitrain
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
14h 39mTrain, ferry
- Take the train from Pisa Centrale to Civitavecchiatrain 4139 / ...
- Take the ferry from Port of Civitavecchia to Port of Palermoferry Itcvv-Itpmo
17h 7m€71–170Bus
- Take the bus from Pisa to Florence Villa Constanza Bus Stationbus N538 / ...
- Take the bus from Florence Villa Constanza Bus Station to Palermobus N597 / ...
19h€50–149Train (Trenitalia)
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
16h 8m€106–284Car ferry
- Take the car ferry from Livorno to Port of Palermocarferry
19h 53m€96–126
Pisa International Airport (PSA) to Palermo Airport (PMO) flights
Questions & Answers
The cheapest way to get from Pisa to Palermo is to bus which costs €50 - €150 and takes 19h.
The fastest way to get from Pisa to Palermo is to fly which takes 2h 22m and costs €40 - €210.
No, there is no direct bus from Pisa to Palermo. However, there are services departing from Pisa and arriving at Palermo via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 19h.
No, there is no direct train from Pisa to Palermo. However, there are services departing from Pisa Centrale and arriving at Palermo Centrale via Firenze S.M.N. and Roma Termini. The journey, including transfers, takes approximately 16h 8m.
The distance between Pisa and Palermo is 685 km.
The best way to get from Pisa to Palermo without a car is to train and ferry via Messina which takes 14h 39m and costs .
It takes approximately 2h 22m to get from Pisa to Palermo, including transfers.
Pisa to Palermo bus services, operated by FlixBus, depart from Pisa station.
Pisa to Palermo train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Palermo is to fly which takes 2h 22m and costs €40 - €210. Alternatively, you can bus, which costs €50 - €150 and takes 19h, you could also train, which costs €100 - €290 and takes 16h 8m.
What companies run services between Pisa, Italy and Palermo, Italy?
Ryanair flies from Pisa International Airport (PSA) to Palermo Airport (PMO) 3 times a day. Alternatively, you can take a bus from Pisa to Palermo via Florence Villa Constanza Bus Station in around 19h.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–190
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 25m
- Frequency
- Every 30 minutes
- Estimated price
- €6–9
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Every 4 hours
- Estimated price
- €13–20
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Civitavecchia
- Ave. Duration
- 2h 58m
- Frequency
- Every 4 hours
- Estimated price
- €15–22
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- 4 times a day
- Estimated price
- €15–23
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Villa San Giovanni
- Ave. Duration
- 7h 9m
- Frequency
- Once daily
- Estimated price
- €100–140
- Website
- https://www.italotreno.it/en
- Smart Economy
- €100–140
- Smart Flex
- €110–140
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- €22–50
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Civitavecchia
- Ave. Duration
- 2h 17m
- Frequency
- 3 times a day
- Estimated price
- €25–60
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- 6 times a week
- Estimated price
- €26–60
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Once daily
- Estimated price
- €85–200
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Civitavecchia
- Ave. Duration
- 2h 7m
- Frequency
- 5 times a day
- Estimated price
- €35–70
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 42m
- Frequency
- Hourly
- Estimated price
- €35–75
- Schedules at
- trenitalia.com
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h
- Frequency
- 4 times a day
- Estimated price
- €5–9
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h
- Frequency
- Twice daily
- Estimated price
- €75–140
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 16h
- Frequency
- Twice a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Ferry from Port of Civitavecchia to Port of Palermo
- Ave. Duration
- 12h
- Frequency
- Once a week
- Estimated price
- €55–99
- Website
- https://www.gnv.it/en
- Seat
- €55–65
- Cabin
- €93–99
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Car ferry from Livorno to Port of Palermo
- Ave. Duration
- 19h 30m
- Frequency
- 3 times a week
- Estimated price
- €40–60
- Website
- https://www.grimaldi-lines.com/en/
Want to know more about travelling around Italy
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More Questions & Answers
Pisa to Palermo bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Pisa to Palermo train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Book your Pisa to Palermo train tickets online with Omio.
Book your Pisa to Palermo bus tickets online with Omio and FlixBus.
There are 5776+ hotels available in Palermo.































