There are 7 ways to get from Pisa to Palermo by plane, train (Trenitalia), bus, ferry, train, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Pisa International Airport
best- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
2h 22m€68–218Bus
cheapest- Take the bus from Pisa to Florence Villa Constanza Bus Stationbus N538 / ...
- Take the bus from Florence Villa Constanza Bus Station to Palermobus N597 / ...
19h 15m€43–162Train
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Florence Santa Maria Novella to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
16h 5m€80–188Ferry
- Take the ferry from Livorno to Port of Palermoferry
21h 28m€46–99Train to Florence Peretola Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane FLR - PMO
5h 13m€72–231Train, bus
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the bus from Florence Villa Constanza Bus Station to Trapani Imbarco Aliscafo Liberty Linesbus
- Take the bus from Trapani Imbarco Aliscafo Liberty Lines to Palermo-Via Libertàbus
22h 39m€70–101Drive, car ferry
- Drive from Pisa to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
22h 40m€86–177
Pisa to Palermo by train
Questions & Answers
The cheapest way to get from Pisa to Palermo is to ferry which costs €45 - €100 and takes 21h 28m.
The fastest way to get from Pisa to Palermo is to fly which takes 2h 22m and costs €65 - €220.
No, there is no direct bus from Pisa to Palermo. However, there are services departing from Pisa and arriving at Palermo via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 19h 15m.
No, there is no direct train from Pisa to Palermo. However, there are services departing from Pisa Centrale and arriving at Palermo Centrale via Florence Santa Maria Novella and Roma Termini. The journey, including transfers, takes approximately 16h 5m.
The distance between Pisa and Palermo is 685 km.
The best way to get from Pisa to Palermo without a car is to train which takes 16h 5m and costs €75 - €190.
It takes approximately 2h 22m to get from Pisa to Palermo, including transfers.
Pisa to Palermo bus services, operated by FlixBus, depart from Pisa station.
Pisa to Palermo train services, operated by Trenitalia S.p.A., depart from Pisa Centrale station.
The best way to get from Pisa to Palermo is to fly which takes 2h 22m and costs €65 - €220. Alternatively, you can train, which costs €75 - €190 and takes 16h 5m, you could also bus, which costs €40 - €170 and takes 19h 15m.
What companies run services between Pisa, Italy and Palermo, Italy?
Ryanair flies from Pisa International Airport (PSA) to Palermo Airport (PMO) twice daily. Alternatively, you can take a train from Pisa Centrale to Palermo Centrale via Florence Santa Maria Novella and Roma Termini in around 16h 5m.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €60–210
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- €70–180
- Website
- volotea.com
Flights from Florence Peretola Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, and Friday
- Estimated price
- €30–170
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €16–24
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €23–55
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Once daily
- Estimated price
- €40–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h
- Frequency
- 5 times a day
- Estimated price
- €8–13
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h 15m
- Frequency
- Twice daily
- Estimated price
- €40–150
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 16h
- Frequency
- Twice a week
- Estimated price
- €35–55
- Schedules at
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Trapani Imbarco Aliscafo Liberty Lines
- Ave. Duration
- 17h 45m
- Frequency
- Twice a week
- Estimated price
- €40–60
- Schedules at
- autoservizisalemi.it
- Phone
- 06 164 160, +39091342525
- info@segesta.it
- Website
- segesta.it
Bus from Trapani Imbarco Aliscafo Liberty Lines to Palermo-Via Libertà
- Ave. Duration
- 1h 36m
- Frequency
- Hourly
- Estimated price
- €11–16
- Schedules at
- segesta.it
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Livorno to Port of Palermo
- Ave. Duration
- 19h 30m
- Frequency
- 3 times a week
- Estimated price
- €45–95
- Website
- https://www.grimaldi-lines.com/en/
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €60–140
- Website
- https://www.gnv.it/en
_-_S%C3%A8te,_2018.jpg "GNV Atlas")
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
How to get from Florence to Rome
Read the travel guide
More Questions & Answers
Pisa to Palermo bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Pisa to Palermo train services, operated by Trenitalia S.p.A., arrive at Firenze S.M.N. station.
Book your Pisa to Palermo train tickets online with Omio.
Book your Pisa to Palermo bus tickets online with Omio and FlixBus.
There are 5705+ hotels available in Palermo.