There are 7 ways to get from Pisa to Lucerne by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Florence
best- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Arth-Goldautrain Ec
7h 20mCHF 92–215Bus
cheapest- Take the bus from Pisa to Milano, Autostazione Lampugnanobus 1500 / ...
- Take the bus from Milan to Luzernbus FlixBus N401 / ...
9h 20mCHF 38–64Drive 521.8 km
- Drive from Pisa to Lucernecar 521.8 km
5h 30mCHF 86–124Fly from Pisa International Airport, train
- Fly from Pisa International Airport (PSA) to Zurich Airport (ZRH)plane PSA - ZRH
- Take the train from Zürich HB to Luzerntrain
4h 47mCHF 101–332Train (Trenitalia)
- Take the train from Pisa Centrale to Milano Centraletrain Ic
- Take the train from Milano Centrale to Arth-Goldautrain Ec
8h 2mCHF 84–197Train #2
- Take the train from Pisa Centrale to Milan Rogoredotrain Ec
- Take the train from Milano Centrale to Luganotrain
- Take the train from Lugano to Luzerntrain Ec
10h 22mCHF 154–452Train to Florence Peretola Airport, fly, train
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Zurich Airport (ZRH)plane FLR - ZRH
- Take the train from Zürich HB to Luzerntrain
6h 13mCHF 127–322
Pisa to Lucerne by train
Questions & Answers
The cheapest way to get from Pisa to Lucerne is to bus which costs SFr 35 - SFr 65 and takes 9h 20m.
The fastest way to get from Pisa to Lucerne is to fly and train which takes 4h 47m and costs SFr 100 - SFr 340.
No, there is no direct bus from Pisa to Lucerne. However, there are services departing from Pisa and arriving at Luzern via Milan. The journey, including transfers, takes approximately 9h 20m.
No, there is no direct train from Pisa to Lucerne. However, there are services departing from Pisa Centrale and arriving at Luzern via Firenze S.M.N., Milano Centrale and Arth-Goldau. The journey, including transfers, takes approximately 7h 20m.
The distance between Pisa and Lucerne is 614 km. The road distance is 521.8 km.
The best way to get from Pisa to Lucerne without a car is to train via Florence which takes 7h 20m and costs SFr 90 - SFr 220.
It takes approximately 7h 20m to get from Pisa to Lucerne, including transfers.
Pisa to Lucerne bus services, operated by FlixBus, depart from Pisa station.
Pisa to Lucerne train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Lucerne is to train via Florence which takes 7h 20m and costs SFr 90 - SFr 220. Alternatively, you can bus, which costs SFr 35 - SFr 65 and takes 9h 20m.
What companies run services between Pisa, Italy and Lucerne, Switzerland?
You can take a train from Pisa Centrale to Luzern via Firenze S.M.N., Milano Centrale, and Arth-Goldau in around 7h 20m. Alternatively, you can take a bus from Pisa to Luzern via Milan in around 9h 20m.
- Website
- swiss.com
Flights from Pisa International Airport to Zurich Airport via Brussels
- Ave. Duration
- 4h 40m
- When
- Tuesday and Saturday
- Estimated price
- CHF 80–250
Flights from Pisa International Airport to Zurich Airport via Cagliari
- Ave. Duration
- 4h 15m
- When
- Wednesday, Friday, Saturday, and Sunday
- Estimated price
- CHF 70–350
Flights from Pisa International Airport to Zurich Airport via Prague
- Ave. Duration
- 4h 35m
- When
- Wednesday, Thursday, and Sunday
- Estimated price
- CHF 80–250
Flights from Florence Peretola Airport to Zurich Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- CHF 90–260
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 15 minutes
- Estimated price
- CHF 9–15
- Website
- Trenitalia
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 4h 25m
- Frequency
- Twice daily
- Estimated price
- CHF 35–60
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 15 minutes
- Estimated price
- CHF 9–15
- Website
- Trenitalia
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Pisa to Milano, Autostazione Lampugnano
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- CHF 23–40
- Website
- Flixbus
Bus from Milan to Luzern
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- CHF 16–27
- Website
- Flixbus
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Pisa to Lucerne bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.
Pisa to Lucerne train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Lucerne is 522 km. It takes approximately 5h 30m to drive from Pisa to Lucerne.
Book your Pisa to Lucerne train tickets online with Omio.
Book your Pisa to Lucerne bus tickets online with Omio and FlixBus.
There are 685+ hotels available in Lucerne.





