There are 7 ways to get from Pisa to Brindisi by plane, train, bus, night train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Brindisi  •  2 h 34 min

  1. Fly from Pisa (PSA) to Brindisi (BDS) PSA - BDS

$47 - $178

6 alternative options

Fly to Bari, train  •  3 h 50 min

  1. Fly from Pisa (PSA) to Bari (BRI) PSA - BRI
  2. Take the train from Bari Centrale to Brindisi

$52 - $197

Train  •  8 h 47 min

  1. Take the train from Pisa C.Le to Firenze Smn Rv / ...
  2. Take the train from Firenze S.Maria Novella to Roma Termini Fr / ...
  3. Take the train from Roma Termini to Brindisi Fa

$100 - $164

Bus FlixBus  •  12 h 40 min

  1. Take the bus from Pisa to Brindisi N548 / ...

$55 - $95

Bus Autolinee Chiruzzi S.R.L.  •  13 h 54 min

  1. Take the bus from Livorno to Massafra
  2. Take the bus from Massafra to Brindisi Milan > Gioia del Colle > Mottola > Massafra > Taranto > Grottaglie > Francavilla Fontana > Brindisi > Lecce > Nardo'

$80 - $121

Train, night train  •  11 h 35 min

  1. Take the train from Pisa Centrale to Roma Termini Fb / ...
  2. Take the night train from Roma Termini to Brindisi Icn

$109 - $147

Drive  •  8 h 51 min

  1. Drive from Pisa to Brindisi 604.5 miles

$140 - $210

What companies run services between Pisa, Italy and Brindisi, Italy?

Ryanair and Alitalia fly from Pisa to Brindisi 4 times a day. Alternatively, you can take a train from Pisa to Brindisi via Firenze Smn, Firenze S.Maria Novella, and Roma Termini in around 8 h 47 min.

Airlines
Alitalia
Website
alitalia.com
Flights from Pisa to Brindisi via Rome
Ave. Duration
3 h 28 min
When
Every day
Estimated price
$100 - $370
Flights from Pisa to Bari via Rome
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$110 - $700
Ryanair
Website
ryanair.com
Flights from Pisa to Brindisi
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$50 - $260
Flights from Pisa to Bari
Ave. Duration
1 h 25 min
When
Every day
Estimated price
$28 - $270
Train operators
Trenitalia Frecce
Phone
+39 06 68475475
Website
trenitalia.com
Train from Bari Centrale to Brindisi
Ave. Duration
52 min
Frequency
Hourly
Estimated price
$19 - $27
Website
orario.trenitalia.com
Train from Firenze S.Maria Novella to Roma Termini
Ave. Duration
1 h 32 min
Frequency
Every 30 minutes
Estimated price
$35 - $55
Website
orario.trenitalia.com
Train from Roma Termini to Brindisi
Ave. Duration
5 h 1 min
Frequency
3 times a day
Estimated price
$65 - $95
Website
orario.trenitalia.com
Train from Pisa Centrale to Roma Termini
Ave. Duration
2 h 56 min
Frequency
Every 4 hours
Estimated price
$40 - $65
Website
orario.trenitalia.com
Trenitalia
ItaloTreno
Phone
+39 060708
Website
italotreno.it
Train from Firenze Santa Maria Novella Station to Roma Termini
Ave. Duration
1 h 32 min
Frequency
Every 3 hours
Estimated price
$29 - $45
Website
italotreno.it
Bus operators
FlixBus
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Pisa to Brindisi
Ave. Duration
12 h 40 min
Frequency
Once daily
Estimated price
$55 - $95
Website
flixbus.co.uk
Marozzi VT
Phone
080 579 0211
Email
info@marozzivt.it
Website
marozzivt.it
Bus from Pisa to Brindisi
Ave. Duration
13 h 20 min
Frequency
Every 3 hours
Estimated price
$70 - $90
Schedules at
marozzivt.it
Autolinee Chiruzzi S.R.L.
Phone
+39 0835 522250
Email
biglietteria@chiruzzi.it
Website
chiruzzi.it
Bus from Livorno to Massafra
Ave. Duration
10 h 58 min
Frequency
Twice a week
Estimated price
$75 - $110
Schedules at
chiruzzi.it
Ouibus
Phone
0890715298
Website
ouibus.com
Bus from Massafra to Brindisi
Ave. Duration
1 h 35 min
Frequency
Every 15 minutes
Estimated price
$3 - $6
Website
Ouibus

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Questions & Answers

The distance between Pisa and Brindisi is 708 km. The road distance is 967 km.

The cheapest way to get from Pisa to Brindisi is to bus which costs 45€ - 80€ and takes 12 h 40 min.

The quickest way to get from Pisa to Brindisi is to fly which takes 2 h 34 min and costs 35€ - 150€.

No, there is no direct train from Pisa to Brindisi. However, there are services departing from Pisa C.Le and arriving at Brindisi via Firenze S.Maria Novella and Roma Termini. The journey, including transfers, takes approximately 8 h 47 min.

Yes, there is a direct bus departing from Pisa and arriving at Brindisi. Services depart every three hours, and operate every day. The journey takes approximately 12 h 40 min.

It takes approximately 2 h 34 min to get from Pisa to Brindisi, including transfers.