• Our partners include:

  • RailEurope
  • Deutsche Bahn
  • Trenitalia
  • SNCF
  • Flixbus
  • RENFE
  • Ouibus
  • BlaBlaCar
  • Booking.com
  • Skyscanner

There are 7 ways to get from Pisa to Brindisi by plane, train, bus, night train, night bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Brindisi  •  2h 1m

  1. Fly from Pisa (PSA) to Brindisi (BDS) PSA - BDS

$47 - $178

Cheapest option

Fly to Bari, train  •  3h 56m

  1. Fly from Pisa (PSA) to Bari (BRI) PSA - BRI
  2. Take the train from Bari Centrale to Brindisi

$40 - $188

5 alternative options

Train  •  8h 38m

  1. Take the train from Pisa C.Le to Firenze Smn Rv / ...
  2. Take the train from Firenze Santa Maria Novella Station to Roma Termini Station Rv / ...
  3. Take the train from Roma Termini to Brindisi Fa

$90 - $153

Bus  •  13h

  1. Take the bus from Pisa, Pisa to Brindisi N548 / ...

$50 - $90

Train, night train  •  12h 44m

  1. Take the train from Pisa Centrale to Roma Termini Rv / ...
  2. Take the night train from Roma Termini to Brindisi Icn

$85 - $130

Bus, night bus  •  17h 35m

  1. Take the bus from Pisa to Siena
  2. Take the night bus from Siena to Brindisi MarinoBus

$75

Drive  •  8h 51m

  1. Drive from Pisa to Brindisi 604.5 miles

$140 - $210

Questions & Answers

The cheapest way to get from Pisa to Brindisi is to bus and night bus which costs 65€ - 66€ and takes 17h 35m.

More details

The quickest way to get from Pisa to Brindisi is to fly which costs 40€ - 160€ and takes 2h 1m.

More details

Yes, there is a direct bus departing from Pisa, Pisa and arriving at Brindisi. Services depart once daily, and operate every day. The journey takes approximately 13h.

More details

No, there is no direct train from Pisa to Brindisi. However, there are services departing from Pisa C.Le and arriving at Brindisi via Firenze Santa Maria Novella Station and Roma Termini. The journey, including transfers, takes approximately 8h 38m.

More details

The distance between Pisa and Brindisi is 708 km. The road distance is 967.2 km.

Get driving directions

The best way to get from Pisa to Brindisi without a car is to train which takes 8h 38m and costs 75€ - 140€.

More details

It takes approximately 2h 1m to get from Pisa to Brindisi, including transfers.

More details

Pisa to Brindisi bus services, operated by FlixBus, depart from Pisa, Pisa station.

More details

Pisa to Brindisi train services, operated by Trenitalia, depart from Pisa C.Le station.

More details

The best way to get from Pisa to Brindisi is to fly which takes 2h 1m and costs 40€ - 160€. Alternatively, you can train, which costs 75€ - 140€ and takes 8h 38m, you could also bus, which costs 45€ - 80€ and takes 13h.

Mode details

Map of how to get from Pisa to Brindisi.
Launch map view
  • Distance: 442.7 miles
  • Duration: 2h 1m

What companies run services between Pisa, Italy and Brindisi, Italy?

Ryanair and Alitalia fly from Pisa to Brindisi 4 times a day. Alternatively, you can take a train from Pisa to Brindisi via Firenze Smn, Firenze Santa Maria Novella Station, Roma Termini Station, and Roma Termini in around 8h 38m.

Airlines
Alitalia
Website
alitalia.com
Flights from Pisa to Brindisi via Rome
Ave. Duration
3h 31m
When
Every day
Estimated price
$100 - $370
Flights from Pisa to Bari via Rome
Ave. Duration
3h 24m
When
Every day
Estimated price
$110 - $700
Ryanair
Website
ryanair.com
Flights from Pisa to Brindisi
Ave. Duration
1h 30m
When
Monday, Wednesday, Friday, Saturday and Sunday
Estimated price
$50 - $260
Flights from Pisa to Bari
Ave. Duration
1h 25m
When
Every day
Estimated price
$28 - $270
Train operators
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Bari Centrale to Brindisi
Ave. Duration
1h 22m
Frequency
Hourly
Estimated price
$8 - $19
Website
orario.trenitalia.com
1st Class
$15 - $19
Train from Pisa C.Le to Firenze Smn
Ave. Duration
1h
Frequency
Every 30 minutes
Estimated price
$6 - $14
Website
orario.trenitalia.com
1st Class
$11 - $14
Train from Firenze S.Maria Novella to Roma Termini
Ave. Duration
3h 38m
Frequency
Every 30 minutes
Estimated price
$19 - $40
Website
orario.trenitalia.com
1st Class
$30 - $40
Train from Pisa Centrale to Roma Termini
Ave. Duration
4h 3m
Frequency
Hourly
Estimated price
$24 - $55
Website
orario.trenitalia.com
1st Class
$40 - $55
ItaloTreno
Phone
+39 060708
Website
italotreno.it
Train from Firenze Santa Maria Novella Station to Roma Termini Station
Ave. Duration
1h 32m
Frequency
Hourly
Estimated price
$27 - $40
Website
italotreno.it
Trenitalia Frecce

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Roma Termini to Brindisi
Ave. Duration
4h 57m
Frequency
3 times a day
Estimated price
$65 - $100
Website
orario.trenitalia.com
Trenitalia Intercity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Night train from Roma Termini to Brindisi
Ave. Duration
7h 41m
Frequency
Once a week
Estimated price
$60 - $80
Website
orario.trenitalia.com
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Pisa, Pisa to Brindisi
Ave. Duration
13h
Frequency
4 times a week
Estimated price
$50 - $90
Website
flixbus.co.uk
Marozzi VT
Phone
080 579 0211
Email
info@marozzivt.it
Website
marozzivt.it
Bus from Pisa to Brindisi
Ave. Duration
13h 20m
Frequency
Once daily
Estimated price
$70 - $85
Website
Marozzi VT
Saj
Phone
0981 500331
Email
info@saj.it
Website
saj.it
Bus from Pisa to Siena
Ave. Duration
2h 30m
Frequency
Once daily
Estimated price
$13
Schedules at
saj.it
Marino Autolinee
Phone
+39 080 3112335
Email
info@marinobus.it
Website
marinobus.it
Night bus from Siena to Brindisi
Ave. Duration
12h 55m
Frequency
Twice a week
Estimated price
$61
Website
Marino Autolinee

Want to know more about travelling around Italy

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Pisa Airport to Brindisi Airport is the direct flight which takes 1h 30m.

Search flights

Pisa to Brindisi bus services, operated by FlixBus, arrive at Brindisi station.

More details

Pisa to Brindisi train services, operated by Trenitalia Frecce, arrive at Brindisi station.

More details

Yes, the driving distance between Pisa to Brindisi is 967 km. It takes approximately 8h 51m to drive from Pisa to Brindisi.

Get driving directions

Ryanair and Alitalia offer flights from Pisa Airport to Brindisi Airport.

Search flights

Book your Pisa to Brindisi bus tickets online with FlixBus and Distribusion.

Search and book

There are 448+ hotels available in Brindisi. Prices start at $46 USD per night.

More details