There are 7 ways to get from Pisa to Brindisi by plane, train, bus, bus and ferry, night train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Brindisi  •  2 h 1 min

  1. Fly from Pisa (PSA) to Brindisi (BDS) PSA - BDS

$47 - $178

6 alternative options

Fly to Bari, train  •  3 h 24 min

  1. Fly from Pisa (PSA) to Bari (BRI) PSA - BRI
  2. Take the train from Bari Centrale to Brindisi

$50 - $195

Train  •  8 h 39 min

  1. Take the train from Pisa C.Le to Firenze Smn Rv / ...
  2. Take the train from Firenze Santa Maria Novella Station to Roma Termini Rv / ...
  3. Take the train from Roma Termini to Brindisi Fa

$90 - $153

Bus  •  12 h 40 min

  1. Take the bus from Pisa to Brindisi N548 / ...

$50 - $90

Train, bus and ferry  •  14 h 20 min

  1. Take the train from Pisa C.Le to Firenze Smn Firenze - Pisa - Livorno / ...
  2. Take the bus and ferry from Firenze to Brindisi

$86 - $133

Train, night train  •  12 h 44 min

  1. Take the train from Pisa Centrale to Roma Termini Rv / ...
  2. Take the night train from Roma Termini to Brindisi Icn

$85 - $131

Drive  •  8 h 51 min

  1. Drive from Pisa to Brindisi 604.5 miles

$140 - $210

Questions & Answers

Yes, there is a direct bus departing from Pisa and arriving at Brindisi. Services depart every three hours, and operate every day. The journey takes approximately 12 h 40 min.

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No, there is no direct train from Pisa to Brindisi. However, there are services departing from Pisa C.Le and arriving at Brindisi via Firenze Santa Maria Novella Station and Roma Termini. The journey, including transfers, takes approximately 8 h 39 min.

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The distance between Pisa and Brindisi is 708 km. The road distance is 967.2 km.

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The best way to get from Pisa to Brindisi without a car is to train which takes 8 h 39 min and costs .

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It takes approximately 2 h 1 min to get from Pisa to Brindisi, including transfers.

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Pisa to Brindisi bus services, operated by FlixBus, depart from Pisa station.

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Pisa to Brindisi train services, operated by Trenitalia, depart from Pisa C.Le station.

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The best way to get from Pisa to Brindisi is to fly which takes 2 h 1 min and costs . Alternatively, you can train, which costs and takes 8 h 39 min, you could also bus, which costs and takes 12 h 40 min.

Mode details

The quickest flight from Pisa Airport to Brindisi Airport is the direct flight which takes 1 h 40 min.

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Pisa to Brindisi bus services, operated by FlixBus, arrive at Brindisi station.

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Map of how to get from Pisa to Brindisi.
Launch map view
  • Distance: 442.7 miles
  • Duration: 2 h 1 min

What companies run services between Pisa, Italy and Brindisi, Italy?

Ryanair and Alitalia fly from Pisa to Brindisi 4 times a day. Alternatively, you can take a train from Pisa to Brindisi via Firenze Smn, Firenze Santa Maria Novella Station, and Roma Termini in around 8 h 39 min.

Airlines
Alitalia
Website
alitalia.com
Flights from Pisa to Brindisi via Rome
Ave. Duration
3 h 31 min
When
Every day
Estimated price
$100 - $370
Flights from Pisa to Bari via Rome
Ave. Duration
3 h 16 min
When
Every day
Estimated price
$110 - $700
Ryanair
Website
ryanair.com
Flights from Pisa to Brindisi
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$50 - $260
Flights from Pisa to Bari
Ave. Duration
1 h 25 min
When
Every day
Estimated price
$28 - $270
Train operators
Trenitalia Frecce

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Bari Centrale to Brindisi
Ave. Duration
52 min
Frequency
Hourly
Estimated price
$18 - $26
Website
orario.trenitalia.com
Train from Roma Termini to Brindisi
Ave. Duration
4 h 57 min
Frequency
Twice daily
Estimated price
$65 - $100
Website
orario.trenitalia.com
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Pisa C.Le to Firenze Smn
Ave. Duration
1 h
Frequency
Every 30 minutes
Estimated price
$6 - $14
Website
orario.trenitalia.com
1st Class
$11 - $14
Train from Firenze S.Maria Novella to Roma Termini
Ave. Duration
3 h 38 min
Frequency
Every 30 minutes
Estimated price
$19 - $40
Website
orario.trenitalia.com
1st Class
$30 - $40
Train from Pisa Centrale to Roma Termini
Ave. Duration
4 h 3 min
Frequency
Hourly
Estimated price
$24 - $55
Website
orario.trenitalia.com
1st Class
$40 - $55
ItaloTreno
Trenitalia Intercity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Night train from Roma Termini to Brindisi
Ave. Duration
7 h 41 min
Frequency
Once a week
Estimated price
$60 - $80
Website
orario.trenitalia.com
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Pisa to Brindisi
Ave. Duration
12 h 40 min
Frequency
5 times a week
Estimated price
$50 - $90
Website
flixbus.co.uk
Marozzi VT
Phone
080 579 0211
Email
info@marozzivt.it
Website
marozzivt.it
Bus from Pisa to Brindisi
Ave. Duration
13 h 20 min
Frequency
Every 3 hours
Estimated price
$70 - $85
Schedules at
marozzivt.it
Florentia Bus
Phone
+39 055 967024
Email
info@florentiabus.it
Website
florentiabus.it
Bus and ferry from Firenze to Brindisi
Ave. Duration
12 h 20 min
Frequency
Once a week
Estimated price
$80 - $120
Schedules at
florentiabus.it

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More Questions & Answers

Pisa to Brindisi train services, operated by Trenitalia Frecce, arrive at Brindisi station.

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Yes, the driving distance between Pisa to Brindisi is 967 km. It takes approximately 8 h 51 min to drive from Pisa to Brindisi.

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Ryanair and Alitalia offer flights from Pisa Airport to Brindisi Airport.

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Book your Pisa to Brindisi train tickets online with Rome2rio.

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Book your Pisa to Brindisi bus tickets online with FlixBus and Distribusion.

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There are 467+ hotels available in Brindisi. Prices start at $52 USD per night.

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