There are 8 ways to get from Philadelphia to Prestonsburg by plane, car, train, bus or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.
Recommended option
Fly Philadelphia to Lexington, drive
-
Fly from Philadelphia (PHL) to Lexington (LEX)
-
Drive from Lexington to Prestonsburg
Cheapest option
Train to Reagan Washington, fly to Charleston, drive
-
Take the train from Philadelphia to Washington Union Station
-
Fly from Reagan Washington (DCA) to Charleston (CRW)
-
Drive from Charleston to Prestonsburg
6 alternative options
Fly Philadelphia to Knoxville, drive
-
Fly from Philadelphia (PHL) to Knoxville (TYS)
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Drive from Knoxville to Prestonsburg
Fly Philadelphia to Asheville, drive
-
Fly from Philadelphia (PHL) to Asheville (AVL)
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Drive from Asheville to Prestonsburg
Fly Philadelphia to Columbus, bus, taxi
-
Fly from Philadelphia (PHL) to Columbus (CMH)
-
Take the bus from Columbus to Ashland
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Take a taxi from Ashland to Prestonsburg
Train, taxi
-
Take the train from Philadelphia to Huntington Amtrak Station
-
Take a taxi from Huntington Amtrak Station to Prestonsburg
Bus, taxi
-
Take the bus from Philadelphia Bus Station to Columbus
-
Take the bus from Columbus to Ashland
-
Take a taxi from Ashland to Prestonsburg
Drive
-
Drive from Philadelphia to Prestonsburg
Travel safe during COVID-19
Rules to follow in United States
2m
Recommended
Travel within United States
Nationwide control measures in place
COVID-19 help in United States
If you need help, visit the national COVID-19 website or call the COVID-19 Helpline 800-232-4636
Frequently Asked Questions
Yes, travel within United States is currently allowed.
Explore travel optionsDomestic travel is not restricted, but some conditions may apply
- Face masks are recommended
- There is a social distancing requirement of 2 metres
- Nationwide control measures in place
The national COVID-19 helpline number in Prestonsburg is 800-232-4636.
Wearing a face mask on public transport in Prestonsburg is recommended.
The social distance requirement in Prestonsburg is 2 metres.
Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 800-232-4636.
Last updated: 3 Aug 2022
Exceptions may apply, for full details: Centers for Disease control and prevention (CDC).
We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.
Questions & Answers
The cheapest way to get from Philadelphia to Prestonsburg is to drive which costs $100 - $160 and takes 10h 7m.
The fastest way to get from Philadelphia to Prestonsburg is to fly and drive. Taking this option will cost $180 - $470 and takes 5h 35m.
The distance between Philadelphia and Prestonsburg is 441 miles. The road distance is 585.5 miles.
The best way to get from Philadelphia to Prestonsburg without a car is to train and taxi which takes 15h 9m and costs $200 - $280.
It takes approximately 5h 35m to get from Philadelphia to Prestonsburg, including transfers.
The quickest flight from Philadelphia Airport to Lexington Airport is the direct flight which takes 1h 53m.
Yes, the driving distance between Philadelphia to Prestonsburg is 585 miles. It takes approximately 10h 7m to drive from Philadelphia to Prestonsburg.
American Airlines and Delta offer flights from Philadelphia Airport to Lexington Airport.
There are seven+ hotels available in Prestonsburg. Prices start at $100 USD per night.
The best way to get from Philadelphia to Philadelphia Airport is to train which takes 22 min and costs $0 - $7.

- Distance: 441.4 miles
- Duration: 5h 35m
What companies run services between Philadelphia, PA, USA and Prestonsburg, KY, USA?
There is no direct connection from Philadelphia to Prestonsburg. However, you can take the train to Airport Terminal A, take the walk to Philadelphia airport, fly to Lexington, then take the drive to Prestonsburg. Alternatively, you can take the train to Airport Terminal A, take the walk to Philadelphia airport, fly to Knoxville, then take the drive to Prestonsburg.

- Website
- aa.com
Flights from Philadelphia to Lexington
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $150 - $500
Flights from Philadelphia to Lexington via Charlotte
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $160 - $550
Flights from Philadelphia to Knoxville
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $200 - $650
Flights from Philadelphia to Knoxville via Charlotte
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $200 - $700
Flights from Philadelphia to Knoxville via Reagan Washington
- Ave. Duration
- 4h 56m
- When
- Monday to Friday
- Estimated price
- $200 - $650
Flights from Reagan Washington to Charleston
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $320 - $600
Flights from Philadelphia to Asheville
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $190 - $650
Flights from Philadelphia to Asheville via Charlotte
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $190 - $650
Flights from Philadelphia to Columbus
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $160 - $650
Flights from Philadelphia to Columbus via Charlotte
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $160 - $650

- Website
- delta.com
Flights from Philadelphia to Lexington via Detroit
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $160 - $420
Flights from Philadelphia to Lexington via Atlanta
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $180 - $450
Flights from Philadelphia to Knoxville via Atlanta
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $220 - $550
Flights from Philadelphia to Knoxville via Detroit
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $230 - $600
Flights from Philadelphia to Asheville via Atlanta
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $210 - $550
Flights from Philadelphia to Columbus via Detroit
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $150 - $420

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.
Rome2rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Philadelphia to Washington Union Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $27 - $170
- Website
- Amtrak Acela
- Business Seat - Child 2-12
- $27 - $85
- Business Seat - Seniors and Active Military
- $45 - $160
- Business Seat - Adult
- $50 - $170
- First Class - Child 2-12
- $80 - $140
- First Class - Senior Citizens and Active Military
- $140 - $260
- First Class - Adult
- $160 - $280

Amtrak’s Northeast Regional train service serves the US’ busy northeast corridor from Virginia to Massachusetts; major stops include Boston, Providence, New York City, Philadelphia, Washington DC and Baltimore. Amenities include Wi-Fi, a quiet car, cafe and business-class seating, and travelling with a small dog or cat is permitted. Book at least 14 days in advance for a cheaper Saver Fare.
Rome2rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-523-6590
- Website
- amtrak.com
Train from Philadelphia to Washington Union Station
- Ave. Duration
- 2h 4m
- Frequency
- Hourly
- Estimated price
- $16 - $100
- Schedules at
- amtrak.com
- Book at
- amtrak.com
- Child 2-12 with paid adult
- $16 - $50
- Reserved Coach Seat
- $30 - $100
- Business Class Seat
- $55 - $140

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.
Rome2rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Philadelphia to Washington Union Station
- Ave. Duration
- 1h 57m
- Frequency
- Every 3 hours
- Estimated price
- $30 - $45
- Website
- Amtrak
- Coach Seat
- $30 - $45
- Premium
- $190 - $270
- Flexi Coach Seat
- $50 - $75
- Business Seat
- $45 - $70
Train from Philadelphia to Huntington Amtrak Station
- Ave. Duration
- 13h 29m
- Frequency
- 3 times a week
- Estimated price
- $65 - $95
- Website
- Amtrak
- Coach Seat
- $65 - $95
- Premium
- $260 - $360
- Flexi Coach Seat
- $120 - $190
- Business Seat
- $130 - $190

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.
Rome2rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100/1-800-231-2222
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Columbus to Ashland
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $19 - $27
- Website
- greyhound.com
- Economy
- $19 - $27
- Flexible
- $35 - $55
Bus from Philadelphia Bus Station to Columbus
- Ave. Duration
- 11h 20m
- Frequency
- Twice daily
- Estimated price
- $55 - $80
- Website
- greyhound.com
- Economy
- $55 - $80
- Flexible
- $85 - $130
- Ave. Duration
- 1h 38m
- Estimated price
- $140 - $170
Sureway Cab
- Phone
- +1-740-532-1515
- Website
- surewaycab.com
Ashland Yellow Cab
- Phone
- +1-606-324-4134
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