There are 11 ways to get from Perugia to Santander by bus, plane, train, car, or train (Trenitalia, TGV, Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Fiumicino International Airport, fly to Santander Airport
best- Take the bus from Perugia to Fiumicino Aeroporto T3bus
- Fly from Fiumicino International Airport (FCO) to Santander Airport (SDR)plane FCO - SDR
9h 10m€83–206Bus to Fiumicino International Airport, fly to Bilbao Airport, bus
cheapest- Take the bus from Perugia to Fiumicino Aeroporto T3bus
- Fly from Fiumicino International Airport (FCO) to Bilbao Airport (BIO)plane FCO - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
9h 44m€57–212Train, bus via Antony
- Take the train from Perugia to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Modanetrain Tgv
- Take the train from Modane to Massy Tgvtrain Tgv
- Take the train from Massy Tgv to St Jean De Luz Cibouretrain Tgv
- Take the bus from Saint-Jean-de-Luz to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
23h 17m€380–616Bus
- Take the bus from Perugia to Florence Villa Constanza Bus Stationbus 466 / ...
- Take the bus from Florence Villa Constanza Bus Station to Bordeauxbus
- Take the bus from Bordeaux to Estación de autobuses de Santanderbus
27h 5m€159–250Drive 1,652.4 km
- Drive from Perugia to Santandercar 1,652.4 km
16h 9m€296–427Train to Florence Peretola Airport, fly to Santander Airport
- Take the train from Perugia to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Santander Airport (SDR)plane FLR - SDR
10h 5m€108–377Train to Bologna Guglielmo Marconi Airport, fly to Santander Airport
- Take the train from Perugia to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Santander Airport (SDR)plane BLQ - SDR
7h 33m€82–266Train to Florence Peretola Airport, fly to Bilbao Airport, bus
- Take the train from Perugia to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Bilbao Airport (BIO)plane FLR - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
9h 39m€102–303Train
- Take the train from Perugia to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Lyon Part Dieutrain Fr
- Take the train from Lyon Part Dieu to Avignon Tgvtrain Tgv
- Take the train from Avignon Tgv to Madrid-Puerta de Atocha-Almudena Grandestrain
- Take the train from Madrid Chamartín to Santandertrain Alv / ...
25h 19m€329–527Train, bus
- Take the train from Perugia to Bologna Centraletrain Ic
- Take the train from Bologna centrale to Padovatrain
- Take the bus from Padova to Estación de autobuses de Santanderbus
29h 51m€160–235Bus via Milan
- Take the bus from Perugia Train Station Bus Stop to Milan Lampugnanobus
- Take the bus from Milano, Autostazione Lampugnano to Bordeaux - Belcier Bus Stopbus
- Take the bus from Bordeaux - Belcier Bus Stop to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
29h 54m€128–229
Perugia to Santander by train and bus
Comparing Your Travel Options
The cheapest way to get from Perugia to Santander is to bus and fly which costs €55 - €220 and takes 9h 44m.
The fastest way to get from Perugia to Santander is to train and fly which takes 7h 33m and costs €80 - €270.
No, there is no direct bus from Perugia to Santander. However, there are services departing from Perugia and arriving at Estación de autobuses de Santander via Florence Villa Constanza Bus Station and Bordeaux. The journey, including transfers, takes approximately 27h 5m.
No, there is no direct train from Perugia to Santander. However, there are services departing from Perugia and arriving at Santander via Torino Porta Susa, Lyon Part Dieu, Avignon Tgv, Madrid-Atocha Cercanías and Madrid Chamartín. The journey, including transfers, takes approximately 25h 19m.
The distance between Perugia and Santander is 1524 km. The road distance is 1652.4 km.
The best way to get from Perugia to Santander without a car is to train and bus via Antony which takes 23h 17m and costs €380 - €650.
It takes approximately 9h 10m to get from Perugia to Santander, including transfers.
Perugia to Santander bus services, operated by FlixBus, depart from Perugia station.
Perugia to Santander train services, operated by Trenitalia Frecce, depart from Perugia station.
The best way to get from Perugia to Santander is to bus which takes 27h 5m and costs €150 - €250. Alternatively, you can train, which costs €320 - €550 and takes 25h 19m.
What companies run services between Perugia, Italy and Santander, Spain?
You can take a bus from Perugia to Estación de autobuses de Santander via Florence Villa Constanza Bus Station and Bordeaux in around 27h 5m. Alternatively, you can take a train from Perugia to Santander via Torino Porta Susa, Lyon Part Dieu, Avignon Tgv, Madrid-Puerta De Atocha-Almudena Grandes, Madrid-Atocha Cercanías, and Madrid Chamartín in around 25h 19m.
- Website
- iberia.com
Flights from Fiumicino International Airport to Santander Airport via Madrid
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- €65–360
Flights from Fiumicino International Airport to Santander Airport via Barcelona
- Ave. Duration
- 6h 55m
- When
- Tuesday, Saturday, and Sunday
- Estimated price
- €45–270
Flights from Florence Peretola Airport to Santander Airport via Madrid
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- €90–240
Flights from Florence Peretola Airport to Santander Airport via Barcelona
- Ave. Duration
- 7h 25m
- When
- Tuesday and Wednesday
- Estimated price
- €90–240
Flights from Bologna Guglielmo Marconi Airport to Santander Airport via Madrid
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- €75–410
Flights from Florence Peretola Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €80–250
Flights from Fiumicino International Airport to Bilbao Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €28–190
Flights from Fiumicino International Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- €28–190
- Website
- vueling.com
Flights from Fiumicino International Airport to Santander Airport via Madrid
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- €65–360
Flights from Fiumicino International Airport to Santander Airport via Barcelona
- Ave. Duration
- 6h 55m
- When
- Tuesday, Saturday, and Sunday
- Estimated price
- €45–270
Flights from Florence Peretola Airport to Santander Airport via Madrid
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- €90–240
Flights from Florence Peretola Airport to Santander Airport via Barcelona
- Ave. Duration
- 7h 25m
- When
- Tuesday and Wednesday
- Estimated price
- €90–240
Flights from Bologna Guglielmo Marconi Airport to Santander Airport via Madrid
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- €75–410
Flights from Florence Peretola Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €80–250
Flights from Fiumicino International Airport to Bilbao Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €28–190
Flights from Fiumicino International Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- €28–190
- Website
- volotea.com
Flights from Fiumicino International Airport to Santander Airport via Madrid
- Ave. Duration
- 10h 30m
- When
- Friday and Sunday
- Estimated price
- €100–320
Flights from Florence Peretola Airport to Santander Airport via Sevilla
- Ave. Duration
- 11h 55m
- When
- Thursday and Sunday
- Estimated price
- €110–390
Flights from Florence Peretola Airport to Bilbao Airport
- Ave. Duration
- 2h 15m
- When
- Tuesday and Saturday
- Estimated price
- €50–170
Flights from Fiumicino International Airport to Bilbao Airport
- Ave. Duration
- 2h 30m
- When
- Monday
- Estimated price
- €30–120
- Website
- flyulendo.com
Flights from Fiumicino International Airport to Santander Airport via Valencia
- Ave. Duration
- 7h 20m
- When
- Tuesday and Saturday
- Estimated price
- €110–190
Flights from Fiumicino International Airport to Bilbao Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €28–150
- Website
- ryanair.com
Flights from Bologna Guglielmo Marconi Airport to Santander Airport
- Ave. Duration
- 2h 20m
- When
- Sunday
- Estimated price
- €65–220
- Website
- swiss.com
Flights from Florence Peretola Airport to Bilbao Airport via Zurich
- Ave. Duration
- 4h 35m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- €70–370
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Perugia to Torino Porta Susa
- Ave. Duration
- 4h 44m
- Frequency
- 6 times a week
- Estimated price
- €80–140
- Website
- Trenitalia Frecce
Train from Perugia to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- 6 times a week
- Estimated price
- €20–35
- Website
- Trenitalia Frecce
Train from Perugia to Bologna Centrale
- Ave. Duration
- 2h 24m
- Frequency
- 6 times a week
- Estimated price
- €30–60
- Website
- Trenitalia Frecce
Train from Perugia to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- 6 times a week
- Estimated price
- €20–35
- Website
- Trenitalia Frecce
Train from Perugia to Torino Porta Susa
- Ave. Duration
- 4h 44m
- Frequency
- 6 times a week
- Estimated price
- €80–140
- Website
- Trenitalia Frecce
Train from Perugia to Bologna Centrale
- Ave. Duration
- 2h 24m
- Frequency
- 6 times a week
- Estimated price
- €30–60
- Website
- Trenitalia Frecce
Train from Bologna centrale to Padova
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- €16–29
- Website
- Trenitalia Frecce
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Torino Porta Susa to Modane
- Ave. Duration
- 1h 22m
- Frequency
- 3 times a day
- Estimated price
- €20–30
- Website
- TGV inOui
Train from Modane to Massy Tgv
- Ave. Duration
- 4h 43m
- Frequency
- 3 times a week
- Estimated price
- €120–190
- Website
- TGV inOui
Train from Massy Tgv to St Jean De Luz Ciboure
- Ave. Duration
- 4h 24m
- Frequency
- 3 times a week
- Estimated price
- €150–230
- Website
- TGV inOui
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 1m
- Frequency
- Every 3 hours
- Estimated price
- €45–70
- Website
- TGV inOui
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Torino Porta Susa to Modane
- Ave. Duration
- 1h 12m
- Frequency
- Twice daily
- Estimated price
- €11–17
- Website
- Trenitalia
Train from Perugia to Firenze S.M.N.
- Ave. Duration
- 2h 12m
- Frequency
- Every 4 hours
- Estimated price
- €18–25
- Website
- Trenitalia
Train from Perugia to Firenze S.M.N.
- Ave. Duration
- 2h 12m
- Frequency
- Every 4 hours
- Estimated price
- €18–25
- Website
- Trenitalia
Train from Torino Porta Susa to Lyon Part Dieu
- Ave. Duration
- 3h 52m
- Frequency
- Twice daily
- Estimated price
- €35–50
- Website
- Trenitalia
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 9m
- Frequency
- Once daily
- Estimated price
- €27–40
- Website
- Trenitalia
Train from Bologna centrale to Padova
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €14–20
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Perugia to Firenze S.M.N.
- Ave. Duration
- 1h 29m
- Frequency
- Once daily
- Estimated price
- €16–30
- Website
- Trenitalia Intercity
Train from Perugia to Bologna Centrale
- Ave. Duration
- 3h 1m
- Frequency
- Once daily
- Estimated price
- €26–50
- Website
- Trenitalia Intercity
Train from Perugia to Firenze S.M.N.
- Ave. Duration
- 1h 29m
- Frequency
- Once daily
- Estimated price
- €16–30
- Website
- Trenitalia Intercity
Train from Perugia to Bologna Centrale
- Ave. Duration
- 3h 1m
- Frequency
- Once daily
- Estimated price
- €26–50
- Website
- Trenitalia Intercity
Train from Bologna centrale to Padova
- Ave. Duration
- 1h 7m
- Frequency
- Twice daily
- Estimated price
- €13–24
- Website
- Trenitalia Intercity
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 2m
- Frequency
- 3 times a day
- Estimated price
- €40–70
- Website
- Oui.SNCF
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 3m
- Frequency
- Once daily
- Estimated price
- €40–65
- Website
- Belgian Railways
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Avignon Tgv to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 7h 37m
- Frequency
- Once daily
- Estimated price
- €130–190
- Website
- Renfe Viajeros
Train from Madrid Chamartín to Santander
- Ave. Duration
- 4h 4m
- Frequency
- 3 times a day
- Estimated price
- €55–80
- Website
- Renfe Viajeros
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Bologna centrale to Padova
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €14–24
- Website
- Italo Treno
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Perugia to Fiumicino Aeroporto T3
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a week
- Estimated price
- €17–26
- Website
- Flixbus
Bus from Saint-Jean-de-Luz to Bilbao Intermodal
- Ave. Duration
- 2h 10m
- Frequency
- 5 times a week
- Estimated price
- €12–18
- Website
- Flixbus
Bus from Perugia to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Every 4 hours
- Estimated price
- €13–21
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Bordeaux
- Ave. Duration
- 17h 10m
- Frequency
- 5 times a week
- Estimated price
- €110–170
- Website
- Flixbus
Bus from Bordeaux to Estación de autobuses de Santander
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €35–60
- Website
- Flixbus
Bus from Perugia to Fiumicino Aeroporto T3
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a week
- Estimated price
- €17–26
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Saint-Jean-de-Luz to Bilbao Intermodal
- Ave. Duration
- 2h
- Frequency
- Every 4 hours
- Estimated price
- €10–17
- Website
- BlaBlaCar Bus
Bus from Milano, Autostazione Lampugnano to Bordeaux - Belcier Bus Stop
- Ave. Duration
- 14h
- Frequency
- 5 times a day
- Estimated price
- €75–130
- Website
- BlaBlaCar Bus
Bus from Bordeaux - Belcier Bus Stop to Bilbao Intermodal
- Ave. Duration
- 5h 10m
- Frequency
- Every 3 hours
- Estimated price
- €26–45
- Website
- BlaBlaCar Bus
- Phone
- +34 910 207 007
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bordeaux - Belcier Bus Stop to Bilbao Intermodal
- Ave. Duration
- 5h 16m
- Frequency
- Twice daily
- Estimated price
- €28–45
- Schedules at
- alsa.es
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Padova to Estación de autobuses de Santander
- Ave. Duration
- 24h 34m
- Frequency
- 3 times a week
- Estimated price
- €120–150
- Schedules at
- tabitatour.ro
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Perugia Train Station Bus Stop to Milan Lampugnano
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- €23–45
- Website
- Itabus S.p.A.
- Phone
- +351 21 75 24 524
- Website
- Rede Expressos
Bus from Bordeaux - Belcier Bus Stop to Bilbao Intermodal
- Ave. Duration
- 5h
- Frequency
- Once a week
- Estimated price
- €21–40
- Website
- Rede Expressos
Want to know more about travelling around Spain
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Booking & Getting There
Perugia to Santander bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Perugia to Santander train services, operated by Trenitalia Frecce, arrive at Torino Porta Susa station.
Yes, the driving distance between Perugia to Santander is 1652 km. It takes approximately 16h 9m to drive from Perugia to Santander.
Book your Perugia to Santander train tickets online with Omio.
Book your Perugia to Santander bus tickets online with Omio, FlixBus and 12go.asia.
There are 1875+ hotels available in Santander.






















































