There are 8 ways to get from Pensacola to St. Louis by plane, taxi, car, bus or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Pensacola to St. Louis  •  5 h 59 min

  1. Fly from Pensacola (PNS) to St. Louis (STL) PNS - STL

$155 - $435

Cheapest option

Bus via Atlanta, Ga  •  21 h 37 min

  1. Take the bus from Pensacola, Fl to Mobile, Al
  2. Take the bus from Mobile, Al to Atlanta, Ga
  3. Take the bus from Atlanta, Ga to St Louis, Mo

$119 - $276

6 alternative options

Taxi to Valparaiso, fly to St. Louis  •  6 h 11 min

  1. Take a taxi from Pensacola to Valparaiso
  2. Fly from Valparaiso (VPS) to St. Louis (STL) VPS - STL

$317 - $1,100

Drive to Panama City, fly to St. Louis  •  4 h 43 min

  1. Drive from Pensacola to Panama City
  2. Fly from Panama City (ECP) to St. Louis (STL) ECP - STL

$185 - $871

Taxi to Valparaiso, fly to Belleville  •  5 h

  1. Take a taxi from Pensacola to Valparaiso
  2. Fly from Valparaiso (VPS) to Belleville (BLV) VPS - BLV

$259 - $622

Bus, train  •  21 h 44 min

  1. Take the bus from Pensacola, Fl to Mobile, Al
  2. Take the bus from Mobile, Al to New Orleans, La
  3. Take the train from New Orleans Union Passenger Terminal to Carbondale Amtrak
  4. Take the bus from Carbondale to St Louis, Mo

$149 - $381

Bus  •  27 h 14 min

  1. Take the bus from Pensacola, Fl to Tallahassee, Fl 1262 / ...
  2. Take the bus from Tallahassee, Fl to St Louis, Mo 1162

$121 - $298

Drive  •  12 h 31 min

  1. Drive from Pensacola to St. Louis 753.9 miles

$70 - $110

Questions & Answers

The cheapest way to get from Pensacola to St. Louis is to drive which costs $70 - $110 and takes 12 h 31 min.

More details

The quickest way to get from Pensacola to St. Louis is to drive and fly which costs $180 - $900 and takes 4 h 43 min.

More details

The distance between Pensacola and St. Louis is 595 miles. The road distance is 753.9 miles.

Get driving directions

The best way to get from Pensacola to St. Louis without a car is to bus which takes 21 h 37 min and costs $110 - $280.

More details

It takes approximately 5 h 59 min to get from Pensacola to St. Louis, including transfers.

More details

The best way to get from Pensacola to St. Louis is to fly which takes 5 h 59 min and costs $150 - $440. Alternatively, you can bus, which costs $110 - $280 and takes 21 h 37 min.

Mode details

There is no direct flight from Pensacola Airport to St. Louis Airport. The quickest flight takes 3 h 51 min and has one stopover.

Search flights

Yes, the driving distance between Pensacola to St. Louis is 754 miles. It takes approximately 12 h 31 min to drive from Pensacola to St. Louis.

Get driving directions

Delta, Southwest Airlines, United Airlines and American Airlines offer flights from Pensacola Airport to St. Louis Airport.

Search flights

There are 185+ hotels available in St. Louis. Prices start at $71 USD per night.

More details

Map of how to get from Pensacola to St. Louis.
Launch map view
  • Distance: 595.2 miles
  • Duration: 5 h 59 min

What companies run services between Pensacola, FL, USA and St. Louis, MO, USA?

Delta, Southwest Airlines and two other airlines fly from Pensacola to St. Louis hourly. Alternatively, you can take a bus from Pensacola to St. Louis via Pensacola, Fl, Mobile, Al, and Atlanta, Ga in around 21 h 37 min.

Airlines
American Airlines
Website
aa.com
Flights from Pensacola to St. Louis via Charlotte
Ave. Duration
5 h 40 min
When
Every day
Estimated price
$310 - $850
Flights from Pensacola to St. Louis via Dallas/Ft.Worth
Ave. Duration
5 h 11 min
When
Every day
Estimated price
$310 - $850
Flights from Pensacola to St. Louis via Reagan Washington
Ave. Duration
5 h 32 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $850
Flights from Pensacola to St. Louis via Miami
Ave. Duration
6 h 51 min
When
Monday to Friday
Estimated price
$310 - $850
Flights from Valparaiso to St. Louis via Charlotte
Ave. Duration
6 h 8 min
When
Every day
Estimated price
$230 - $1,100
Flights from Valparaiso to St. Louis via Dallas/Ft.Worth
Ave. Duration
5 h 20 min
When
Every day
Estimated price
$240 - $1,100
Flights from Valparaiso to St. Louis via Reagan Washington
Ave. Duration
7 h 24 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,100
Delta
Website
delta.com
Flights from Pensacola to St. Louis via Atlanta
Ave. Duration
4 h 46 min
When
Every day
Estimated price
$350 - $1,100
Flights from Valparaiso to St. Louis via Atlanta
Ave. Duration
4 h 50 min
When
Every day
Estimated price
$190 - $950
Flights from Valparaiso to St. Louis via Atlanta, Covington
Ave. Duration
5 h 31 min
When
Monday to Friday
Estimated price
$210 - $1,000
Flights from Panama City to St. Louis via Atlanta
Ave. Duration
4 h 21 min
When
Every day
Estimated price
$170 - $850
United Airlines
Website
united.com
Flights from Pensacola to St. Louis via Houston
Ave. Duration
4 h 57 min
When
Every day
Estimated price
$330 - $900
Flights from Pensacola to St. Louis via Chicago O'Hare
Ave. Duration
4 h 49 min
When
Every day
Estimated price
$330 - $900
Flights from Valparaiso to St. Louis via Houston
Ave. Duration
5 h 40 min
When
Every day
Estimated price
$250 - $1,100
Southwest Airlines
Website
southwest.com
Flights from Pensacola to St. Louis via Chicago Midway
Ave. Duration
4 h 30 min
When
Saturday
Estimated price
$450 - $800
Flights from Pensacola to St. Louis via Houston Hobby Apt
Ave. Duration
5 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$450 - $800
Flights from Pensacola to St. Louis via Nashville
Ave. Duration
5 h 51 min
When
Every day
Estimated price
$450 - $800
Flights from Panama City to St. Louis
Ave. Duration
1 h 45 min
When
Saturday
Estimated price
$190 - $800
Allegiant Air
Website
allegiantair.com
Flights from Valparaiso to Belleville
Ave. Duration
1 h 42 min
When
Tuesday, Thursday, Saturday and Sunday
Estimated price
$130 - $470
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New Orleans Union Passenger Terminal to Carbondale Amtrak
Ave. Duration
13 h 26 min
Frequency
Once daily
Estimated price
$85 - $250
Website
amtrak.com
Coach Seat
$85 - $130
Flexi Coach Seat
$150 - $230
Business Coach Seat
$170 - $250
Room
$370 - $550
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Pensacola, Fl to Mobile, Al
Ave. Duration
2 h 5 min
Frequency
Every 15 minutes
Estimated price
$12 - $26
Website
greyhound.com
Economy
$12 - $17
Flexible
$20 - $26
Bus from Mobile, Al to Atlanta, Ga
Ave. Duration
5 h 40 min
Frequency
Every 30 minutes
Estimated price
$35 - $90
Website
greyhound.com
Economy
$35 - $60
Flexible
$65 - $90
Bus from Atlanta, Ga to St Louis, Mo
Ave. Duration
12 h 50 min
Frequency
Hourly
Estimated price
$55 - $140
Website
greyhound.com
Economy
$55 - $90
Flexible
$100 - $140
Bus from Mobile, Al to New Orleans, La
Ave. Duration
2 h 20 min
Frequency
Every 30 minutes
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $45
Bus from Carbondale to St Louis, Mo
Ave. Duration
2 h 5 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$29 - $40
Bus from Pensacola, Fl to Tallahassee, Fl
Ave. Duration
6 h 15 min
Frequency
Hourly
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $40
Flexible
$45 - $65
Bus from Tallahassee, Fl to St Louis, Mo
Ave. Duration
18 h 35 min
Frequency
Every 3 hours
Estimated price
$85 - $220
Website
greyhound.com
Economy
$85 - $140
Flexible
$160 - $220
Other operators
Taxi from Pensacola to Valparaiso
Ave. Duration
1 h 9 min
Estimated price
$120 - $150
Choice Taxi
Phone
+1 850-529-1806
Website
mychoicetaxi.com
Able Shuttle and Taxi
Phone
+1 850-607-0209
Website
pensacolaairportshuttle.co

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