There are 5 ways to get from Pensacola to St. Louis by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  2 h 33 min

  1. Fly from Pensacola (PNS) to St. Louis (STL) PNS - STL

$166 - $449

Cheapest option

Bus via Atlanta, Ga  •  21 h 37 min

  1. Take the bus from Pensacola, Fl to Mobile, Al
  2. Take the bus from Mobile, Al to Atlanta, Ga
  3. Take the bus from Atlanta, Ga to St Louis, Mo

$119 - $276

3 alternative options

Bus, train  •  21 h 44 min

  1. Take the bus from Pensacola, Fl to Mobile, Al
  2. Take the bus from Mobile, Al to New Orleans, La
  3. Take the train from New Orleans Union Passenger Terminal Amtrak to Carbondale Amtrak
  4. Take the bus from Carbondale to St Louis, Mo

$149 - $381

Bus  •  26 h

  1. Take the bus from Pensacola, Fl to Tallahassee, Fl 1262 / ...
  2. Take the bus from Tallahassee, Fl to St Louis, Mo 1162

$128 - $305

Drive  •  12 h 31 min

  1. Drive from Pensacola to St. Louis 753.9 miles

$70 - $110

What companies run services between Pensacola, FL, USA and St. Louis, MO, USA?

Southwest Airlines and Delta fly from Pensacola to St. Louis 3 times a day. Alternatively, you can take a bus from Pensacola to St. Louis via Pensacola, Fl, Mobile, Al, and Atlanta, Ga in around 21 h 37 min.

Airlines
Delta
Website
delta.com
Flights from Pensacola to St. Louis via Atlanta
Ave. Duration
4 h 9 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$350 - $1,100
Southwest Airlines
Website
southwest.com
Flights from Pensacola to St. Louis
Ave. Duration
1 h 45 min
When
Saturday
Estimated price
$450 - $800
Flights from Pensacola to St. Louis via Kansas City
Ave. Duration
4 h 25 min
When
Saturday
Estimated price
$450 - $800
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New Orleans Union Passenger Terminal Amtrak to Carbondale Amtrak
Ave. Duration
13 h 26 min
Frequency
Once daily
Estimated price
$85 - $250
Website
amtrak.com
Coach Seat
$85 - $130
Flexi Coach Seat
$150 - $230
Business Coach Seat
$170 - $250
Room
$370 - $550
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Pensacola, Fl to Mobile, Al
Ave. Duration
2 h 5 min
Frequency
Every 15 minutes
Estimated price
$12 - $26
Website
greyhound.com
Economy
$12 - $17
Flexible
$20 - $26
Bus from Mobile, Al to Atlanta, Ga
Ave. Duration
5 h 40 min
Frequency
Every 30 minutes
Estimated price
$35 - $90
Website
greyhound.com
Economy
$35 - $60
Flexible
$65 - $90
Bus from Atlanta, Ga to St Louis, Mo
Ave. Duration
12 h 50 min
Frequency
Hourly
Estimated price
$55 - $140
Website
greyhound.com
Economy
$55 - $90
Flexible
$100 - $140
Bus from Mobile, Al to New Orleans, La
Ave. Duration
2 h 20 min
Frequency
Every 30 minutes
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $45
Bus from Carbondale to St Louis, Mo
Ave. Duration
2 h 5 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$29 - $40
Bus from Pensacola, Fl to Tallahassee, Fl
Ave. Duration
6 h 15 min
Frequency
Hourly
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $40
Flexible
$45 - $65
Bus from Tallahassee, Fl to St Louis, Mo
Ave. Duration
18 h 35 min
Frequency
Every 3 hours
Estimated price
$85 - $220
Website
greyhound.com
Economy
$85 - $140
Flexible
$160 - $220

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

The distance between Pensacola and St. Louis is 952 km. The road distance is 1206 km.

The cheapest way to get from Pensacola to St. Louis is to drive which costs $70 - $110 and takes 12 h 31 min.

The quickest way to get from Pensacola to St. Louis is to fly which takes 2 h 33 min and costs $160 - $450.

It takes approximately 2 h 33 min to get from Pensacola to St. Louis, including transfers.