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There are 7 ways to get from Pensacola to St. Louis by plane, car, taxi, bus or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Pensacola to St. Louis  •  3h 49m

  1. Fly from Pensacola (PNS) to St. Louis (STL) PNS - STL

$155 - $435

Cheapest option

Bus  •  20h 15m

  1. Take the bus from Pensacola, Fl to Mobile, Al
  2. Take the bus from Mobile, Al to Montgomery, Al
  3. Take the bus from Montgomery, Al to St Louis, Mo

$111 - $251

5 alternative options

Drive to Panama City, fly to St. Louis  •  4h 43m

  1. Drive from Pensacola to Panama City
  2. Fly from Panama City (ECP) to St. Louis (STL) ECP - STL

$185 - $871

Taxi to Valparaiso, fly to Belleville  •  4h 57m

  1. Take a taxi from Pensacola to Valparaiso
  2. Fly from Valparaiso (VPS) to Belleville (BLV) VPS - BLV

$259 - $622

Taxi to Valparaiso, fly to Evansville, bus  •  7h 17m

  1. Take a taxi from Pensacola to Valparaiso
  2. Fly from Valparaiso (VPS) to Evansville (EVV) VPS - EVV
  3. Take the bus from Evansville, In to St Louis, Mo

$300 - $691

Bus, train, Amtrak Thruway  •  23h 1m

  1. Take the bus from Pensacola, Fl to Mobile, Al
  2. Take the bus from Mobile, Al to New Orleans, La
  3. Take the train from New Orleans Union Passenger Terminal to Carbondale Amtrak Station
  4. Take the Amtrak Thruway from Carbondale,IL - Amtrak to St. Louis, MO - Amtrak

Drive  •  12h 31m

  1. Drive from Pensacola to St. Louis 753.9 miles

$70 - $110

Questions & Answers

The cheapest way to get from Pensacola to St. Louis is to drive which costs $70 - $110 and takes 12h 31m.

More details

The quickest way to get from Pensacola to St. Louis is to fly which costs $150 - $440 and takes 3h 49m.

More details

The distance between Pensacola and St. Louis is 595 miles. The road distance is 753.9 miles.

Get driving directions

The best way to get from Pensacola to St. Louis without a car is to bus which takes 20h 15m and costs $110 - $260.

More details

It takes approximately 3h 49m to get from Pensacola to St. Louis, including transfers.

More details

The best way to get from Pensacola to St. Louis is to fly which takes 3h 49m and costs $150 - $440. Alternatively, you can bus, which costs $110 - $260 and takes 20h 15m.

Mode details

The quickest flight from Pensacola Airport to St. Louis Airport is the direct flight which takes 1h 45m.

Search flights

Yes, the driving distance between Pensacola to St. Louis is 754 miles. It takes approximately 12h 31m to drive from Pensacola to St. Louis.

Get driving directions

Southwest Airlines and Delta offer flights from Pensacola Airport to St. Louis Airport.

Search flights

There are 200+ hotels available in St. Louis. Prices start at $65 USD per night.

More details

Map of how to get from Pensacola to St. Louis.
Launch map view
  • Distance: 595.2 miles
  • Duration: 3h 49m

What companies run services between Pensacola, FL, USA and St. Louis, MO, USA?

Southwest Airlines and Delta fly from Pensacola to St. Louis 3 times a week. Alternatively, you can take a bus from Pensacola to St. Louis via Pensacola, Fl, Mobile, Al, and Montgomery, Al in around 20h 15m.

Airlines
Delta
Website
delta.com
Flights from Pensacola to St. Louis via Atlanta
Ave. Duration
4h 3m
When
Saturday and Sunday
Estimated price
$350 - $1,100
Flights from Panama City to St. Louis via Atlanta
Ave. Duration
4h 12m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $850
Flights from Valparaiso to Evansville via Atlanta
Ave. Duration
3h 40m
When
Every day
Estimated price
$180 - $950
Southwest Airlines
Website
southwest.com
Flights from Pensacola to St. Louis
Ave. Duration
1h 45m
When
Saturday
Estimated price
$450 - $800
Flights from Panama City to St. Louis
Ave. Duration
1h 50m
When
Monday to Friday
Estimated price
$190 - $800
Allegiant Air
Website
allegiantair.com
Flights from Valparaiso to Belleville
Ave. Duration
1h 44m
When
Thursday and Sunday
Estimated price
$130 - $470
Flights from Valparaiso to Evansville
Ave. Duration
1h 35m
When
Thursday and Sunday
Estimated price
$130 - $460
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from New Orleans Union Passenger Terminal to Carbondale Amtrak Station
Ave. Duration
13h 26m
Frequency
Twice daily
Estimated price
$85 - $250
Website
amtrak.com
Coach Seat
$85 - $130
Flexi Coach Seat
$150 - $230
Business Coach Seat
$170 - $250
Room
$370 - $550
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Evansville, In to St Louis, Mo
Ave. Duration
3h 20m
Frequency
Twice daily
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Pensacola, Fl to Mobile, Al
Ave. Duration
2h 5m
Frequency
Every 2 hours
Estimated price
$12 - $26
Website
greyhound.com
Economy
$12 - $17
Flexible
$20 - $26
Bus from Mobile, Al to Montgomery, Al
Ave. Duration
2h 35m
Frequency
Hourly
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Montgomery, Al to St Louis, Mo
Ave. Duration
13h 30m
Frequency
Once daily
Estimated price
$60 - $150
Website
greyhound.com
Economy
$60 - $100
Flexible
$110 - $150
Bus from Mobile, Al to New Orleans, La
Ave. Duration
2h 20m
Frequency
Every 2 hours
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $45
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Bus from Mobile to New Orleans
Ave. Duration
2h 20m
Frequency
Once daily
Website
amtrak.com
Bus from Carbondale,IL - Amtrak to St. Louis, MO - Amtrak
Ave. Duration
2h
Frequency
Once daily
Website
amtrak.com
Other operators
Taxi from Pensacola to Valparaiso
Ave. Duration
1h 9m
Estimated price
$120 - $150
Choice Taxi
Phone
+1 850-529-1806
Website
mychoicetaxi.com
Able Shuttle and Taxi
Phone
+1 850-607-0209
Website
pensacolaairportshuttle.co

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The best way to get from Pensacola to Pensacola Airport is to line 31 bus which takes 15m and costs $2.

More details