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How to get fromPensacola to Iowaby plane, taxi, bus, train, bus (Flixbus, Greyhound) or car

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There are 8 ways to get from Pensacola to Iowa by plane, taxi, bus, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Pensacola International Airport to Des Moines

    best
    1. Fly from Pensacola International Airport (PNS) to Des Moines (DSM)plane plane PNS - DSM
    7h 32m
    $106–495

  2. Fly Pensacola International Airport to Quad City International Airport

    cheapest
    1. Fly from Pensacola International Airport (PNS) to Quad City International Airport (MLI)plane plane PNS - MLI
    8h 34m
    $96–486

  3. Taxi, bus, train

    1. Take the taxi from Pensacola to Mobiletaxi taxi
    2. Take the bus from Mobile to Biloxibus bus
    3. Take the bus from Biloxi Transit Center to New Orleans Bus Stationbus bus
    4. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train
    5. Take the bus from Chicago Bus Station to Des Moinesbus bus
    33h 20m
    $430–816

  4. Bus

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    33h 46m
    $238–505

  5. Drive 1,017.6 mi

    1. Drive from Pensacola to Des Moinescar car 1,017.6 mi
    19h 7m
    $186–269

  6. Fly Pensacola International Airport to Omaha

    1. Fly from Pensacola International Airport (PNS) to Omaha (OMA)plane plane PNS - OMA
    7h 30m
    $259–1,334

  7. Fly Pensacola International Airport to Waterloo Municipal Airport

    1. Fly from Pensacola International Airport (PNS) to Waterloo Municipal Airport (ALO)plane plane PNS - ALO
    9h 52m
    $121–525

  8. Bus to Destin–Fort Walton Beach Airport, fly to Quad City International Airport

    1. Take the bus from Pensacola to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Quad City International Airport (MLI)plane plane VPS - MLI
    8h 6m
    $169–530

Pensacola International Airport (PNS) to Des Moines (DSM) flights

Calendar57Weekly Planes
Duration6h 15mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

What companies run services between Pensacola, FL, USA and Iowa, USA?

Delta, American Airlines, and two other airlines fly from Pensacola International Airport (PNS) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Pensacola to Des Moines via Tallahassee, N Monroe Street and Silver Slipper Lane, Tallahassee, Atlanta Bus Station, Chicago Bus Station, and Des Moines in around 33h 46m.

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