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How to get fromPennsylvania to Chicagoby plane, train (Amtrak), bus (Flixbus), car, bus or bus (Greyhound)

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There are 11 ways to get from Pennsylvania to Chicago by plane, train (Amtrak), bus (Flixbus), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Erie International Airport to Chicago O'Hare International Airport

    best
    1. Fly from Erie International Airport (ERI) to Chicago O'Hare International Airport (ORD)plane plane ERI - ORD
    4h 30m
    $49–297

  2. Train via Washington (Amtrak)

    1. Take the train from 30th Street Station to Washington Union Stationtrain train Northeast Regional
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train Floridian
    21h 14m
    $195–469

  3. Bus

    1. Take the bus from Philadelphia 30th St Station to Allentown Transportation Centerbus bus Philadelphia
    2. Take the bus from Allentown to Chicago Bus Stationbus bus FlixBus N2640
    21h 17m
    $133–218

  4. Drive 758.2 mi

    1. Drive from Philadelphia to Chicagocar car 758.2 mi
    12h 27m
    $139–200

  5. Bus to Pittsburgh International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane plane PIT - MDW
    4h 29m

  6. Bus to Pittsburgh International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane plane PIT - ORD
    4h 52m

  7. Fly Philadelphia International Airport to Chicago Midway International Airport

    1. Fly from Philadelphia International Airport (PHL) to Chicago Midway International Airport (MDW)plane plane PHL - MDW
    4h 23m
    $100–558

  8. Fly Lehigh Valley International Airport to Chicago O'Hare International Airport

    1. Fly from Lehigh Valley International Airport (ABE) to Chicago O'Hare International Airport (ORD)plane plane ABE - ORD
    4h 39m
    $49–287

  9. Fly Philadelphia International Airport to Chicago O'Hare International Airport

    1. Fly from Philadelphia International Airport (PHL) to Chicago O'Hare International Airport (ORD)plane plane PHL - ORD
    4h 44m
    $105–438

  10. Bus via Baltimore

    1. Take the bus from Philadelphia to Baltimorebus bus New York
    2. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    23h 24m
    $138–278

  11. Train (Amtrak)

    1. Take the train from 30th Street Station to Chicago Union Stationtrain train Cardinal
    27h 49m
    $233–553

Pennsylvania to Chicago by subway and train (Amtrak)

Calendar7Weekly Services
Duration21h 14mAverage Duration
Ticket$195Cheapest Price
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Questions & Answers

What companies run services between Pennsylvania, USA and Chicago, IL, USA?

American Airlines and United Airlines fly from Erie International Airport (ERI) to Chicago O'Hare International Airport (ORD) twice daily. Alternatively, you can take a subway from 15th St/City Hall to Chicago Union Station via Drexel Station at 30th St, 30th Street Station, Washington, Columbus Circle, Union Station, Union Station, Red Line Center Platform, Rockville, Red Line Center Platform, and Rockville Amtrak in around 21h 14m.

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