From Orly Sud train to Antony Ratp, RER to Paris Est, then train to Luxembourg. 3hrs 46min 48€. From Orly Sud bus to Marne la Vallée-Chessy, train to Metz Ville, then train to Luxembourg. 4hrs 32min 83€. From Paris Orly Airport (ORY) drive to Luxembourg. 3hrs 32min 63€. From Orly Sud train to Antony Ratp, RER to Paris CDG airport, fly to Luxembourg airport, then line 16 bus to Luxembourg. 3hrs 30min 149€.