Panama travel plans with the routes already figured out
Rome2Rio itineraries for Panama are made from a decade of travellers telling us their favourite ways to get from A to B. Personalise these itineraries to take you from A to B to C... and then all the way back home.
7 days in Panama
Panama City SantiagoItinerary navigation
Day 1: Panama City, Panama
Activities
- Bridge of the Americas
- Miraflores Locks Visitors Center
Hotel
RecommendedHotel
Day 2: Colón, Panama
Distance
PopularTransport
- Take the bus from Panama City to Colónbus
1h 15m
$2–6
Activities
- Fuerte Sherman
- Panama Canal Railway Scenic Ride
Hotel
RecommendedHotel
Days 3–5: Tocumen, Panama
Distance
PopularTransport
- Take the bus from Colón to Tocumenbus
- Take the bus from Colón to Tocumenbus
2h 24m
$4–6
Activities
- Amador Causeway
- Biomuseo
Hotel
RecommendedHotel
Day 6: David, Panama
Distance
PopularTransport
- Fly from Tocumen to Davidplane
- Take the taxi from Tocumen to Davidtaxi
1h 22m
$90–596
Activities
- Volcan Baru National Park Hike
- Museo de Historia y Arte Jose de Obaldia
Hotel
RecommendedHotel
Day 7: Santiago, Panama
Distance
PopularTransport
- Take the bus from David to Santiagobus
2h 30m
$15–35
Activities
- Mirador de Santiago
- Restaurante El Patio
Hotel
RecommendedHotel
8 days in Panama
Panama City PenonoméItinerary navigation
Day 1: Panama City, Panama
Activities
- Taboga Island
- Gamboa Rainforest Resort Aerial Tram
Hotel
RecommendedHotel
Day 2: Colón, Panama
Distance
PopularTransport
- Take the bus from Panama City to Colónbus
1h 15m
$2–6
Activities
- Gatun Locks Panama Canal
- Cathedral of the Immaculate Conception
Hotel
RecommendedHotel
Days 3–5: Tocumen, Panama
Distance
PopularTransport
- Take the bus from Colón to Tocumenbus
- Take the bus from Colón to Tocumenbus
2h 24m
$4–6
Activities
- Biomuseo
- Miraflores Locks Visitor Center
Hotel
RecommendedHotel
Day 6: David, Panama
Distance
PopularTransport
- Fly from Tocumen to Davidplane
- Take the taxi from Tocumen to Davidtaxi
1h 22m
$90–596
Activities
- Chiriqui Mall
- Playa La Barqueta
Hotel
RecommendedHotel
Day 7: Santiago, Panama
Distance
PopularTransport
- Take the bus from David to Santiagobus
2h 30m
$15–35
Activities
- Parque Central de Santiago
- Catedral Santiago Apostol
Hotel
RecommendedHotel
Day 8: Penonomé, Panama
Distance
PopularTransport
- Take the bus from Santiago to Penonomébus
1h 37m
$4–24
Activities
- Catedral San Juan Bautista
- Zarati River Kayaking
Hotel
RecommendedHotel
