Panama travel plans with the routes already figured out
Rome2Rio itineraries for Panama are made from a decade of travellers telling us their favourite ways to get from A to B. Personalise these itineraries to take you from A to B to C... and then all the way back home.
7 days in Panama
Panama City TocumenItinerary navigation
Days 1–2: Panama City, Panama
Activities
- Panama Viejo
- Gamboa Rainforest Resort Aerial Tram
Hotel
RecommendedHotel
Day 3: Colón, Panama
Distance
PopularTransport
- Take the bus from Panama City to Colónbus
1h 15m
$NaN–NaN
Activities
- Statue of Christopher Columbus
- Fuerte Sherman
Hotel
RecommendedHotel
Day 4: Santiago, Panama
Distance
PopularTransport
- Take the bus from Colón to Santiagobus
- Take the bus from Colón to Santiagobus
4h 58m
$NaN–NaN
Activities
- Paseo de los Poetas
- Iglesia San Juan de Dios
Hotel
RecommendedHotel
Day 5: David, Panama
Distance
PopularTransport
- Take the bus from Santiago to Davidbus
2h 30m
$NaN–NaN
Activities
- Coffee Farm Tour Boquete
- Plaza Terronal
Hotel
RecommendedHotel
Day 6: Penonomé, Panama
Distance
PopularTransport
- Take the bus from David to Penonomébus
4h 33m
$NaN–NaN
Activities
- Zarati River Kayaking
- Balneario Las Mendozas
Hotel
RecommendedHotel
Day 7: Tocumen, Panama
Distance
PopularTransport
- Take the bus from Penonomé to Tocumenbus
- Take the transfer from Penonomé to Tocumentransfer
- Take the subway from Penonomé to Tocumensubway
- Take the subway from Penonomé to Tocumensubway
2h 47m
$NaN–NaN
Activities
- Los Pueblos Shopping Center
- Mercado de Mariscos Seafood Market
Hotel
RecommendedHotel
8 days in Panama
Panama City TocumenItinerary navigation
Days 1–2: Panama City, Panama
Activities
- Gamboa Rainforest Resort Aerial Tram
- Mercado de Mariscos
Hotel
RecommendedHotel
Day 3: Colón, Panama
Distance
PopularTransport
- Take the bus from Panama City to Colónbus
1h 15m
$NaN–NaN
Activities
- Portobelo National Park
- Colon 2000 Cruise Terminal
Hotel
RecommendedHotel
Day 4: Santiago, Panama
Distance
PopularTransport
- Take the bus from Colón to Santiagobus
- Take the bus from Colón to Santiagobus
4h 58m
$NaN–NaN
Activities
- Cascada El Salto
- Catedral Santiago Apostol
Hotel
RecommendedHotel
Day 5: David, Panama
Distance
PopularTransport
- Take the bus from Santiago to Davidbus
2h 30m
$NaN–NaN
Activities
- Museo de Historia y Arte Jose de Obaldia
- Plaza Terronal
Hotel
RecommendedHotel
Day 6: Penonomé, Panama
Distance
PopularTransport
- Take the bus from David to Penonomébus
4h 33m
$NaN–NaN
Activities
- Explore La Pintada Town
- Chorro de Ola Waterfalls
Hotel
RecommendedHotel
Days 7–8: Tocumen, Panama
Distance
PopularTransport
- Take the bus from Penonomé to Tocumenbus
- Take the transfer from Penonomé to Tocumentransfer
- Take the subway from Penonomé to Tocumensubway
- Take the subway from Penonomé to Tocumensubway
2h 47m
$NaN–NaN
Activities
- Metromall Shopping Center
- Los Pueblos Shopping Center
Hotel
RecommendedHotel
9 days in Panama
Panama City TocumenItinerary navigation
Days 1–2: Panama City, Panama
Activities
- Church of San Jose
- El Valle de Anton
Hotel
RecommendedHotel
Day 3: Colón, Panama
Distance
PopularTransport
- Take the bus from Panama City to Colónbus
1h 15m
$NaN–NaN
Activities
- Playa Langosta
- Zona Libre de Colon
Hotel
RecommendedHotel
Day 4: Santiago, Panama
Distance
PopularTransport
- Take the bus from Colón to Santiagobus
- Take the bus from Colón to Santiagobus
4h 58m
$NaN–NaN
Activities
- Rio Santa Maria Kayaking
- Plaza 5 de Mayo
Hotel
RecommendedHotel
Day 5: David, Panama
Distance
PopularTransport
- Take the bus from Santiago to Davidbus
2h 30m
$NaN–NaN
Activities
- Boquete Hot Springs
- Parque Miguel de Cervantes Saavedra
Hotel
RecommendedHotel
Day 6: Penonomé, Panama
Distance
PopularTransport
- Take the bus from David to Penonomébus
4h 33m
$NaN–NaN
Activities
- Museo de Penonome
- Parque 8 de Diciembre
Hotel
RecommendedHotel
Days 7–9: Tocumen, Panama
Distance
PopularTransport
- Take the bus from Penonomé to Tocumenbus
- Take the transfer from Penonomé to Tocumentransfer
- Take the subway from Penonomé to Tocumensubway
- Take the subway from Penonomé to Tocumensubway
2h 47m
$NaN–NaN
Activities
- Tocumen Airport Observation Deck
- Cinta Costera Waterfront Promenade
Hotel
RecommendedHotel