There are 4 ways to get from Panama City to Guatemala City by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  5h 58m

  1. Fly from Panama City (PTY) to Guatemala City (GUA) PTY - GUA

$236 - $466

Cheapest option

Bus  •  45h 22m

  1. Take the bus from Panama City to San José
  2. Take the bus from San José to Managua
  3. Take the bus from Managua to Guatemala City

$143 - $151

2 alternative options

Bus via Tegucigalpa  •  43h 50m

  1. Take the bus from Panama Terminal Tica Bus to San Jose Terminal Tica Bus
  2. Take the bus from San José to Tegucigalpa Hotel Alameda
  3. Take the bus from Tegucigalpa Marriott Hotel to Guatemala City Holiday Inn

$176 - $189

Drive  •  28h 16m

  1. Drive from Panama City to Guatemala City 1911.6 km

$130 - $200

Questions & Answers

There is ongoing community transmission in Guatemala.
Last Updated: 3/11/2020 | Source: CDC.

Travel restrictions may apply and transportation services are subject to change. Please check before you travel.

Learn More.

The cheapest way to get from Panama City to Guatemala City is to bus which costs $140 - $155 and takes 45h 22m.

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The quickest way to get from Panama City to Guatemala City is to fly which costs $230 - $470 and takes 5h 58m.

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No, there is no direct bus from Panama City to Guatemala City. However, there are services departing from Panama Terminal Tica Bus and arriving at Guatemala City Holiday Inn via San José and Tegucigalpa Marriott Hotel. The journey, including transfers, takes approximately 43h 50m.

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The distance between Panama City and Guatemala City is 1351 km. The road distance is 1911.6 km.

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The best way to get from Panama City to Guatemala City without a car is to bus via Tegucigalpa which takes 43h 50m and costs $170 - $190.

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It takes approximately 5h 58m to get from Panama City to Guatemala City, including transfers.

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Panama City to Guatemala City bus services, operated by Tica Bus, depart from Panama Terminal Tica Bus station.

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The best way to get from Panama City to Guatemala City is to fly which takes 5h 58m and costs $230 - $470. Alternatively, you can bus via Tegucigalpa, which costs $170 - $190 and takes 43h 50m.

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The quickest flight from Panama City Airport to Guatemala City Airport is the direct flight which takes 2h 24m.

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What companies run services between Panama City, Panama and Guatemala City, Guatemala?

Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Panama City to Guatemala City every 3 hours. Alternatively, you can take a bus from Panama City to Guatemala City via San Jose Terminal Tica Bus, San José, Tegucigalpa Hotel Alameda, and Tegucigalpa Marriott Hotel in around 43h 50m.

Airlines
Copa Airlines
Website
copaair.com
Flights from Panama City to Guatemala City
Ave. Duration
2h 25m
When
Every day
Estimated price
$260 - $390
Flights from Panama City to Guatemala City via San Jose
Ave. Duration
4h 38m
When
Every day
Estimated price
$260 - $390
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Panama City to Guatemala City via San Jose
Ave. Duration
3h 55m
When
Every day
Estimated price
$300 - $460
Flights from Panama City to Guatemala City via San Salvador
Ave. Duration
4h 16m
When
Every day
Estimated price
$300 - $460
Bus operators
Tica Bus
Website
ticabus.com
Bus from Panama Terminal Tica Bus to San Jose Terminal Tica Bus
Ave. Duration
16h 45m
Frequency
Twice daily
Estimated price
$50 - $65
Schedules at
ticabus.com
Book at
ticabus.com
Pullmantur
Phone
(502) 2495-7000, (504) 2232-0216 / 2232-0194 / 2232-0197
Email
informacion@pullmantur.com
Website
pullmantur.com
Bus from Tegucigalpa Marriott Hotel to Guatemala City Holiday Inn
Ave. Duration
11h
Frequency
Once daily
Estimated price
$64
Schedules at
pullmantur.com
Nica Bus
Phone
(506) 2221-2679, (506) 2221-2581
Bus from San José to Managua
Ave. Duration
8h
Frequency
3 times a day
Estimated price
$30
Schedules at
nicabus.com.ni

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More Questions & Answers

Panama City to Guatemala City bus services, operated by Pullmantur, arrive at Guatemala City Holiday Inn station.

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Guatemala City is 1h behind Panama City. It is currently 2:26 PM in Panama City and 1:26 PM in Guatemala City.

Yes, the driving distance between Panama City to Guatemala City is 1912 km. It takes approximately 28h 16m to drive from Panama City to Guatemala City.

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Avianca - Aerovías del Continente Americano S.A. and Copa Airlines offer flights from Panama City Airport to Guatemala City Airport.

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There are 227+ hotels available in Guatemala City. Prices start at $100 USD per night.

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The best way to get from Panama City to Panama City Airport is to shuttle which takes 55 min and costs $75.

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