There are 4 ways to get from Panama City to Guatemala City by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  5 h 46 min

  1. PTY - GUA

$176 - $676

Cheapest option

Bus  •  2 days 5 h

  1. Panama-San Jose

$131 - $171

2 alternative options

Bus via San Salvador Terminal San Benito  •  41 h 16 min

$139 - $248

Drive  •  27 h 53 min

  1. 1184.9 miles

$130 - $200

What companies run services between Panama City, Panama and Guatemala City, Guatemala?

Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Panama City to Guatemala City every 4 hours. Alternatively, you can take a bus from Panama City to Guatemala City via San Jose Terminal Tica Bus, San José, San Salvador Terminal San Benito, and San Salvador Hotel Sheraton Presidente in around 41 h 16 min.

Airlines
Copa Airlines
Website
copaair.com
Flights from Panama City to Guatemala City
Ave. Duration
2 h 27 min
When
Every day
Estimated price
$150 - $1,100
Flights from Panama City to Guatemala City via San Jose
Ave. Duration
4 h 35 min
When
Every day
Estimated price
$150 - $1,100
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Panama City to Guatemala City via San Salvador
Ave. Duration
4 h 6 min
When
Every day
Estimated price
$100 - $1,200
Bus operators
Tica Bus
Website
ticabus.com
Bus from Panama Albrook to San Jose Terminal Tica Bus
Ave. Duration
14 h
Frequency
Twice daily
Estimated price
$40 - $90
Schedules at
ticabus.com
Bus from San José to San Salvador Terminal San Benito
Ave. Duration
20 h 40 min
Frequency
Once daily
Estimated price
$70 - $110
Schedules at
ticabus.com
Bus from San José to Guatemala City Tica Bus Calzada Raul Aguilar Batres
Ave. Duration
32 h
Frequency
Once daily
Estimated price
$90 - $130
Schedules at
ticabus.com
Pullmantur
Phone
(502) 2495-7000, (504) 2232-0216 / 2232-0194 / 2232-0197
Email
informacion@pullmantur.com
Website
pullmantur.com
Bus from San Salvador Hotel Sheraton Presidente to Guatemala City Holiday Inn
Ave. Duration
4 h 30 min
Frequency
4 times a day
Estimated price
$29 - $50
Schedules at
pullmantur.com

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Questions & Answers

The distance between Panama City and Guatemala City is 1351 km. The road distance is 1896 km.

The cheapest way to get from Panama City to Guatemala City is to bus which costs $130 - $180 and takes 2 days 5 h.

The quickest way to get from Panama City to Guatemala City is to fly which takes 5 h 46 min and costs $170 - $700.

No, there is no direct bus from Panama City to Guatemala City. However, there are services departing from Panama Albrook and arriving at Guatemala City Holiday Inn via San José and San Salvador Hotel Sheraton Presidente. The journey, including transfers, takes approximately 41 h 16 min.

It takes approximately 5 h 46 min to get from Panama City to Guatemala City, including transfers.