• Our partners include:

  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
  • Megabus
  • SuperShuttle
  • Booking.com
  • Skyscanner
  • Airbnb
  • Expedia

There are 4 ways to get from Panama City to Indianapolis by plane, car or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Panama City  •  5 h 14 min

  1. Fly from Panama City (ECP) to Indianapolis (IND) ECP - IND

$213 - $874

Cheapest option

Bus  •  26 h 30 min

  1. Take the bus from Panama City, Fl to Tallahassee, Fl
  2. Take the bus from Tallahassee, Fl to Louisville, Ky
  3. Take the bus from Louisville, KY to Indianapolis, IN

$111 - $251

2 alternative options

Drive to Valparaiso, fly  •  6 h 16 min

  1. Drive from Panama City to Valparaiso
  2. Fly from Valparaiso (VPS) to Indianapolis (IND) VPS - IND

$189 - $912

Drive  •  13 h 15 min

  1. Drive from Panama City to Indianapolis 757.7 miles

$70 - $110

Questions & Answers

The cheapest way to get from Panama City to Indianapolis is to drive which costs $70 - $110 and takes 13 h 15 min.

More details

The quickest way to get from Panama City to Indianapolis is to fly which costs $210 - $900 and takes 5 h 14 min.

More details

No, there is no direct bus from Panama City to Indianapolis. However, there are services departing from Panama City, Fl and arriving at Indianapolis, IN via Tallahassee, Fl and Louisville, KY. The journey, including transfers, takes approximately 26 h 30 min.

More details

The distance between Panama City and Indianapolis is 668 miles. The road distance is 757.7 miles.

Get driving directions

The best way to get from Panama City to Indianapolis without a car is to bus which takes 26 h 30 min and costs $110 - $260.

More details

It takes approximately 5 h 14 min to get from Panama City to Indianapolis, including transfers.

More details

Panama City to Indianapolis bus services, operated by Greyhound USA, depart from Panama City, Fl station.

More details

The best way to get from Panama City to Indianapolis is to fly which takes 5 h 14 min and costs $210 - $900. Alternatively, you can bus, which costs $110 - $260 and takes 26 h 30 min.

Mode details

There is no direct flight from Panama City Airport to Indianapolis Airport. The quickest flight takes 3 h 35 min and has one stopover.

Search flights

Panama City to Indianapolis bus services, operated by Hoosier Ride, arrive at Indianapolis, IN station.

More details

Map of how to get from Panama City to Indianapolis.
Launch map view
  • Distance: 668.4 miles
  • Duration: 5 h 14 min

What companies run services between Panama City, FL, USA and Indianapolis, IN, USA?

Delta, American Airlines and two other airlines fly from Panama City to Indianapolis hourly. Alternatively, you can take a bus from Panama City to Indianapolis via Tallahassee, Fl, Louisville, Ky, and Louisville, KY in around 26 h 30 min.

Airlines
Delta
Website
delta.com
Flights from Panama City to Indianapolis via Atlanta
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$150 - $800
Flights from Valparaiso to Indianapolis via Atlanta
Ave. Duration
4 h 3 min
When
Every day
Estimated price
$180 - $900
American Airlines
Website
aa.com
Flights from Panama City to Indianapolis via Charlotte
Ave. Duration
5 h 14 min
When
Every day
Estimated price
$180 - $850
Flights from Panama City to Indianapolis via Dallas/Ft.Worth
Ave. Duration
6 h 12 min
When
Every day
Estimated price
$220 - $900
Flights from Panama City to Indianapolis via Chicago O'Hare
Ave. Duration
7 h 48 min
When
Saturday
Estimated price
$190 - $850
Flights from Valparaiso to Indianapolis via Charlotte
Ave. Duration
5 h 11 min
When
Every day
Estimated price
$210 - $950
Southwest Airlines
Website
southwest.com
Flights from Panama City to Indianapolis via Baltimore
Ave. Duration
6 h 10 min
When
Saturday
Estimated price
$240 - $900
Flights from Panama City to Indianapolis via Dallas
Ave. Duration
6 h 40 min
When
Saturday
Estimated price
$250 - $950
Flights from Panama City to Indianapolis via Houston Hobby Apt
Ave. Duration
8 h 10 min
When
Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $950
United Airlines
Website
united.com
Flights from Panama City to Indianapolis via Houston
Ave. Duration
5 h 48 min
When
Every day
Estimated price
$220 - $1,000
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Panama City, Fl to Tallahassee, Fl
Ave. Duration
3 h 15 min
Frequency
Every 4 hours
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$28 - $40
Bus from Tallahassee, Fl to Louisville, Ky
Ave. Duration
17 h 45 min
Frequency
Twice daily
Estimated price
$65 - $170
Website
greyhound.com
Economy
$65 - $110
Flexible
$130 - $170

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Indianapolis is 1 h ahead of Panama City. It is currently 11:13 PM in Panama City and 12:13 AM in Indianapolis.

Yes, the driving distance between Panama City to Indianapolis is 758 miles. It takes approximately 13 h 15 min to drive from Panama City to Indianapolis.

Get driving directions

United Airlines, Southwest Airlines, Delta and American Airlines offer flights from Panama City Airport to Indianapolis Airport.

Search flights

There are 259+ hotels available in Indianapolis. Prices start at $67 USD per night.

More details

The best way to get from Panama City to Panama City Airport is to taxi which takes 35 min and costs $60 - $75.

More details