There are 8 ways to get from Palo Alto to San Diego by train, plane, bus, subway, night bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Caltrain to San Jose, fly  •  3 h 35 min

  1. SJC - SAN

$83 - $340

Cheapest option

Night bus, bus  •  10 h 53 min

  1. 6743 / ...
  2. 9465

$56 - $135

6 alternative options

Fly from San Francisco  •  3 h 52 min

  1. SFO - SAN

$80 - $325

Bus, BART to Oakland, fly  •  4 h 5 min

  1. OAK - SAN

$94 - $367

Bus  •  11 h 5 min

  1. 6853 / ...
  2. 9465

$56 - $135

Caltrain, bus  •  14 h 9 min

  1. Local / ...
  2. Northern CA-Southern CA

$92 - $94

Train  •  16 h 17 min

  1. Coast Starlight
  2. Pacific Surfliner

$99 - $260

Drive  •  8 h 4 min

  1. 479 miles

$45 - $70

What companies run services between Palo Alto, CA, USA and San Diego, CA, USA?

Alaska Airlines, Inc., Southwest Airlines and three other airlines fly from Palo Alto to San Diego hourly. Alternatively, you can take a bus from Palo Alto to San Diego via San Jose Diridon Caltrain, San Jose, Ca, and Los Angeles, Ca in around 11 h 5 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from San Jose to San Diego
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$140 - $650
Flights from San Francisco to San Diego
Ave. Duration
1 h 33 min
When
Every day
Estimated price
$150 - $650
Flights from Oakland to San Diego
Ave. Duration
1 h 28 min
When
Every day
Estimated price
$150 - $700
Alaska Airlines, Inc.
Website
alaskaair.com
Flights from San Jose to San Diego
Ave. Duration
1 h 28 min
When
Every day
Estimated price
$80 - $500
Flights from San Francisco to San Diego
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$130 - $550
United Airlines
Website
united.com
Flights from San Francisco to San Diego
Ave. Duration
1 h 32 min
When
Every day
Estimated price
$110 - $550
Train operators
Caltrain
Website
caltrain.com
Train from California Ave Caltrain to Santa Clara Caltrain
Ave. Duration
24 min
Frequency
Every 30 minutes
Estimated price
$3 - $5
Schedules at
caltrain.com
Train from California Ave Caltrain to San Francisco Caltrain
Ave. Duration
1 h 7 min
Frequency
Every 30 minutes
Estimated price
$6 - $9
Schedules at
caltrain.com
BART
Website
bart.gov
Subway from Union City to Coliseum
Ave. Duration
20 min
Frequency
Every 15 minutes
Estimated price
$3 - $5
Schedules at
bart.gov
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from San Jose Diridon Station Amtrak to Los Angeles Union Station Amtrak
Ave. Duration
10 h 53 min
Frequency
Once daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$290 - $400
Train from Los Angeles Union Station Amtrak to San Diego Santa Fe Depot Amtrak
Ave. Duration
2 h 54 min
Frequency
Every 2 hours
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
Bus operators
AC Transit
Website
actransit.org
Bus from Middlefield Rd:Willow Rd to Union City BART
Ave. Duration
33 min
Frequency
Hourly
Estimated price
$3
Schedules at
actransit.org
Book at
actransit.org
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from San Jose, Ca to Los Angeles, Ca
Ave. Duration
7 h 15 min
Frequency
Hourly
Estimated price
$35 - $90
Website
greyhound.com
Economy
$35 - $60
Flexible
$70 - $90
Bus from Los Angeles, Ca to San Diego, Ca
Ave. Duration
2 h 20 min
Frequency
Hourly
Estimated price
$17 - $40
Website
greyhound.com
Economy
$17 - $26
Flexible
$30 - $40
Xe Do Hoang Transportation
Phone
+1 408-729-7885 / +1-888-834-9336
Website
xedohoang.com
Bus from San Francisco, CA to San Diego, CA
Ave. Duration
10 h 30 min
Frequency
Once daily
Estimated price
$80
Schedules at
xedohoang.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

The distance between Palo Alto and San Diego is 694 km. The road distance is 766 km.

The cheapest way to get from Palo Alto to San Diego is to drive which costs $45 - $70 and takes 8 h 4 min.

The quickest way to get from Palo Alto to San Diego is to Caltrain and fly which takes 3 h 35 min and costs $80 - $340.

No, there is no direct train from Palo Alto to San Diego. However, there are services departing from California Ave Caltrain and arriving at San Diego Santa Fe Depot Amtrak via San Jose Diridon Station Amtrak and Los Angeles Union Station Amtrak. The journey, including transfers, takes approximately 16 h 17 min.

It takes approximately 3 h 35 min to get from Palo Alto to San Diego, including transfers.