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There are 8 ways to get from Palo Alto to San Diego by train, plane, bus, subway or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Caltrain to San Jose, fly  •  3 h 30 min

  1. Take the Caltrain from California Ave Caltrain to Santa Clara Caltrain
  2. Fly from San Jose (SJC) to San Diego (SAN) SJC - SAN

$84 - $344

Cheapest option

Bus Flixbus USA  •  12 h 43 min

  1. Take the bus from San Jose to San Diego FlixBus

$21 - $36

6 alternative options

Bus, BART to Oakland, fly  •  4 h

  1. Take the bus from Middlefield Rd:Lytton Av to Union City BART
  2. Take the BART from Union City BART Station to Coliseum BART Station
  3. Fly from Oakland (OAK) to San Diego (SAN) OAK - SAN

$94 - $367

Caltrain to San Francisco, fly  •  4 h 4 min

  1. Take the Caltrain from Palo Alto Caltrain to Millbrae Caltrain
  2. Fly from San Francisco (SFO) to San Diego (SAN) SFO - SAN

$81 - $327

Bus, train  •  12 h 16 min

  1. Take the bus from San Jose, CA to Los Angeles, CA
  2. Take the train from Los Angeles Union Station Amtrak to San Diego Santa Fe Depot Pacific Surfliner

$65 - $126

Train  •  16 h 18 min

  1. Take the train from San Jose Diridon Station to Los Angeles Union Station Amtrak Coast Starlight
  2. Take the train from Los Angeles Union Station Amtrak to San Diego Santa Fe Depot Pacific Surfliner

$100 - $261

Bus Tufesa  •  16 h 52 min

  1. Take the bus from San Jose, CA to Tijuana

$75 - $118

Drive  •  8 h 4 min

  1. Drive from Palo Alto to San Diego 479 miles

$45 - $70

Questions & Answers

The cheapest way to get from Palo Alto to San Diego is to bus which costs $21 - $40 and takes 12 h 43 min.

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The quickest way to get from Palo Alto to San Diego is to Caltrain and fly which costs $80 - $350 and takes 3 h 30 min.

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No, there is no direct bus from Palo Alto to San Diego. However, there are services departing from El Camino & California and arriving at Broadway & 3rd Av via San Jose and Old Town Transit Center. The journey, including transfers, takes approximately 12 h 43 min.

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No, there is no direct train from Palo Alto to San Diego. However, there are services departing from California Ave Caltrain and arriving at San Diego Santa Fe Depot via San Jose Diridon Station and Los Angeles Union Station Amtrak. The journey, including transfers, takes approximately 16 h 18 min.

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The distance between Palo Alto and San Diego is 434 miles. The road distance is 479 miles.

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The best way to get from Palo Alto to San Diego without a car is to bus and train which takes 12 h 16 min and costs $65 - $130.

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It takes approximately 3 h 30 min to get from Palo Alto to San Diego, including transfers.

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Palo Alto to San Diego bus services, operated by Flixbus USA, depart from San Jose station.

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Palo Alto to San Diego train services, operated by Amtrak, arrive at San Jose Diridon Station.

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The best way to get from Palo Alto to San Diego is to bus which takes 12 h 43 min and costs $21 - $40. Alternatively, you can train, which costs $100 - $270 and takes 16 h 18 min.

Mode details

Map of how to get from Palo Alto to San Diego.
Launch map view
  • Distance: 433.6 miles
  • Duration: 3 h 30 min

What companies run services between Palo Alto, CA, USA and San Diego, CA, USA?

Flixbus USA operates a bus from Palo Alto to San Diego 4 times a week. Tickets cost $17 - $29 and the journey takes 9 h 50 min. Alternatively, you can take a train from Palo Alto to San Diego via San Jose Diridon Caltrain, San Jose Diridon Station, and Los Angeles Union Station Amtrak in around 16 h 18 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from San Jose to San Diego
Ave. Duration
1 h 19 min
When
Every day
Estimated price
$140 - $650
Flights from Oakland to San Diego
Ave. Duration
1 h 26 min
When
Every day
Estimated price
$150 - $700
Flights from San Francisco to San Diego
Ave. Duration
1 h 33 min
When
Every day
Estimated price
$150 - $650
United Airlines
Website
united.com
Flights from San Francisco to San Diego
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$110 - $550
Alaska Airlines, Inc.
Website
alaskaair.com
Flights from San Jose to San Diego
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$80 - $500
Flights from San Francisco to San Diego
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$130 - $550
Train operators
Caltrain
Phone
+1 650-508-6200
Website
caltrain.com
Train from California Ave Caltrain to Santa Clara Caltrain
Ave. Duration
24 min
Frequency
Hourly
Estimated price
$4 - $6
Schedules at
caltrain.com
Train from Palo Alto Caltrain to Millbrae Caltrain
Ave. Duration
34 min
Frequency
Hourly
Estimated price
$5 - $7
Schedules at
caltrain.com
BART
Phone
94604-2688
Website
bart.gov
Subway from Union City BART Station to Coliseum BART Station
Ave. Duration
20 min
Frequency
Every 15 minutes
Estimated price
$3 - $5
Website
bart.gov
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Los Angeles Union Station Amtrak to San Diego Santa Fe Depot
Ave. Duration
2 h 55 min
Frequency
Every 2 hours
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
Train from San Jose Diridon Station to Los Angeles Union Station Amtrak
Ave. Duration
10 h 53 min
Frequency
Once daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$290 - $400
Bus operators
AC Transit
Website
actransit.org
Bus from Middlefield Rd:Lytton Av to Union City BART
Ave. Duration
33 min
Frequency
Hourly
Estimated price
$3
Schedules at
actransit.org
Book at
actransit.org
Flixbus USA
Phone
(855) 626-8585
Website
flixbus.com
Bus from San Jose to San Diego
Ave. Duration
9 h 50 min
Frequency
4 times a week
Estimated price
$17 - $29
Schedules at
flixbus.com
Tufesa
Phone
7022546899
Email
serviciosvegas@hotmail.com
Website
tufesabus.com
Bus from San Jose, CA to Tijuana
Ave. Duration
13 h
Frequency
Once daily
Estimated price
$70 - $110
Book at
GotoBus

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from San Jose Airport to San Diego Airport is the direct flight which takes 1 h 15 min.

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Palo Alto to San Diego bus services, operated by Flixbus USA, arrive at San Diego station.

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Palo Alto to San Diego train services, operated by Amtrak, arrive at San Diego Santa Fe Depot station.

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Yes, the driving distance between Palo Alto to San Diego is 479 miles. It takes approximately 8 h 4 min to drive from Palo Alto to San Diego.

Get driving directions

Alaska Airlines, Inc. and Southwest Airlines offer flights from San Jose Airport to San Diego Airport.

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There are 1105+ hotels available in San Diego. Prices start at $71 USD per night.

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