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How to get fromPalermo to Santanderby plane, car ferry, car, train, bus, or ferry

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There are 8 ways to get from Palermo to Santander by plane, car ferry, car, train, bus, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Santander Airport

    best
    1. Fly from Palermo Airport (PMO) to Santander Airport (SDR)plane plane PMO - SDR
    7h 44m
    €94–375

  2. Fly to Bilbao Airport, bus

    cheapest
    1. Fly from Palermo Airport (PMO) to Bilbao Airport (BIO)plane plane PMO - BIO
    2. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    8h 3m
    €93–441

  3. Car ferry, drive

    1. Take the carferry from Port of Palermo to Port of Genoacarferry car ferry
    2. Drive from Port of Genoa to Santandercar car
    31h 54m
    €323–474

  4. Train, bus

    1. Take the train from Palermo Centrale to Roma Terminitrain train Ic
    2. Take the train from Roma Termini to Milano Centraletrain train
    3. Take the train from Milano Centrale to Lyon Part Dieutrain train Fr
    4. Take the train from Lyon Part Dieu to Massy Tgvtrain train Tgv
    5. Take the train from Massy Tgv to Bordeaux St Jeantrain train Tgv
    6. Take the bus from Bordeaux to Santanderbus bus
    33h 41m
    €427–704

  5. Bus

    1. Take the bus from Palermo to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Bordeauxbus bus
    3. Take the bus from Bordeaux to Santanderbus bus
    42h 30m
    €258–397

  6. Car ferry, bus, train

    1. Take the carferry from Port of Palermo to Port of Genoacarferry car ferry
    2. Take the bus from Genoa to Marseillebus bus
    3. Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain train
    4. Take the train from Madrid Chamartín to Santandertrain train Alv / ...
    41h 48m
    €324–491

  7. Ferry, car ferry, train

    1. Take the ferry from Palermo to Civitavecchiaferry ferry
    2. Take the carferry from Port of Civitavecchia to Port de Barcelonacarferry car ferry
    3. Take the train from Barcelona-Sants to Bilbao-Abandotrain train Alv
    4. Take the train from Bilbao to Santandertrain train
    47h 9m
    €243–382

  8. Bus, train

    1. Take the bus from Palermo Piazza Cairoli to Verona Porta Nuova Stationbus bus
    2. Take the train from Verona Porta Nuova to Padovatrain train Fr
    3. Take the bus from Padova to Estación de autobuses de Santanderbus bus
    2d 2h
    €338–451

Palermo to Santander by train, foot, and bus

Calendar2Weekly Services
Duration33h 41mAverage Duration
Ticket€427Cheapest Price
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Comparing Your Travel Options

Map of how to get from Palermo to Santander.ExpandLaunch map view
  • Distance: 1,566.6 km
  • Duration: 7h 44m

What companies run services between Palermo, Italy and Santander, Spain?

Ryanair and Iberia fly from Palermo Airport (PMO) to Santander Airport (SDR) once daily. Alternatively, you can take a bus from Palermo to Santander via Florence Villa Constanza Bus Station and Bordeaux in around 42h 30m.

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Want to know more about travelling around Spain

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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