There are 7 ways to get from Palermo to Santander by plane, car ferry, car, train, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Palermo Airport (PMO) to Santander Airport (SDR)plane PMO - SDR
10h 49m€64–285Car ferry, drive
- Take the car ferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Santandercar
33h 6m€255–424Train, bus
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Milano Centraletrain Fr / ...
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
- Take the train from Lyon Part Dieu to Massy Tgvtrain Tgv
- Take the train from Massy Tgv to Bordeaux St Jeantrain Tgv
- Take the bus from Bordeaux to Santanderbus
34h 32m€217–777Bus via Bordeaux
- Take the bus from Palermo to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Bordeauxbus
- Take the bus from Bordeaux to Santanderbus
42h 45m€115–287Ferry, bus
- Take the ferry from Port of Palermo to Port of Civitavecchiaferry
- Take the ferry from Port of Civitavecchia to Port de Barcelonaferry
- Take the bus from Barcelona, Estació d'Autobusos Nord to Santander E.A.bus
44h€182–293Ferry, train, bus
- Take the ferry from Port of Palermo to Port of Civitavecchiaferry
- Take the ferry from Port of Civitavecchia to Port de Barcelonaferry
- Take the train from Barcelona-Sants to Bilbao-Abandotrain Alv
- Take the bus from Bilbao Intermodal to Santander E.A.bus
44h 32m€151–265Bus
- Take the bus from Palermo Via Tommaso Fazello to Milano, San Donato M3bus
- Take the bus from Milano, Autostazione Lampugnano to Vitoria Gasteiz Central Bus Stationbus
- Take the bus from Vitoria-Gasteiz to Santander E.A.bus
47h 47m€133–196
Palermo to Santander by train, foot, and bus
Questions & Answers
The cheapest way to get from Palermo to Santander is to fly which costs €60 - €290 and takes 10h 49m.
The fastest way to get from Palermo to Santander is to fly which takes 10h 49m and costs €60 - €290.
No, there is no direct bus from Palermo to Santander. However, there are services departing from Palermo and arriving at Santander via Florence Villa Constanza Bus Station and Bordeaux. The journey, including transfers, takes approximately 42h 45m.
The distance between Palermo and Santander is 1567 km.
The best way to get from Palermo to Santander without a car is to train and bus which takes 34h 32m and costs €210 - €800.
It takes approximately 10h 49m to get from Palermo to Santander, including transfers.
Palermo to Santander bus services, operated by FlixBus, depart from Palermo station.
The best way to get from Palermo to Santander is to fly which takes 10h 49m and costs €60 - €290. Alternatively, you can bus via Bordeaux, which costs €110 - €290 and takes 42h 45m.
Palermo to Santander bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Book your Palermo to Santander bus tickets online with Omio and FlixBus.
What companies run services between Palermo, Italy and Santander, Spain?
Ryanair, Iberia, and Vueling Airlines fly from Palermo Airport (PMO) to Santander Airport (SDR) once daily. Alternatively, you can take a bus from Palermo to Santander via Florence Villa Constanza Bus Station and Bordeaux in around 42h 45m.
- Website
- iberia.com
Flights from Palermo Airport to Santander Airport via Madrid
- Ave. Duration
- 10h 50m
- When
- Monday, Thursday, and Sunday
- Estimated price
- €75–330
Flights from Palermo Airport to Santander Airport via Barcelona
- Ave. Duration
- 17h 10m
- When
- Wednesday and Sunday
- Estimated price
- €60–280
- Website
- vueling.com
Flights from Palermo Airport to Santander Airport via Barcelona
- Ave. Duration
- 17h 10m
- When
- Wednesday and Sunday
- Estimated price
- €60–280
Flights from Palermo Airport to Santander Airport via Madrid
- Ave. Duration
- 10h
- When
- Sunday
- Estimated price
- €75–300
- Website
- ryanair.com
Flights from Palermo Airport to Santander Airport via Charleroi
- Ave. Duration
- 11h 10m
- When
- Saturday
- Estimated price
- €85–320
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 29m
- Frequency
- Once daily
- Estimated price
- €27–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 8m
- Frequency
- Every 30 minutes
- Estimated price
- €35–110
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 40m
- Frequency
- Every 2 hours
- Estimated price
- €45–120
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 39m
- Frequency
- Twice daily
- Estimated price
- €50–140
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Lyon Part Dieu to Massy Tgv
- Ave. Duration
- 2h 1m
- Frequency
- Every 4 hours
- Estimated price
- €45–130
- Website
- https://www.sncf-connect.com/en-en
Train from Massy Tgv to Bordeaux St Jean
- Ave. Duration
- 2h 58m
- Frequency
- 5 times a day
- Estimated price
- €40–130
- Website
- https://www.sncf-connect.com/en-en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Lyon Part Dieu to Massy Tgv
- Ave. Duration
- 2h 1m
- Frequency
- Every 4 hours
- Estimated price
- €70–160
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €70–110
- Rail 1st Class
- €110–160
Train from Massy Tgv to Bordeaux St Jean
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- €90–200
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €90–130
- Rail 1st Class
- €130–200
- Phone
- +33 2 22 55 00 10
- nomad-car@laregionnormandie.fr
- Website
- nomad.normandie.fr
Train from Lyon Part Dieu to Massy Tgv
- Ave. Duration
- 2h 7m
- Frequency
- 5 times a week
- Schedules at
- nomad.normandie.fr
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Barcelona-Sants to Bilbao-Abando
- Ave. Duration
- 7h 3m
- Frequency
- Once daily
- Estimated price
- €25–75
- Website
- https://www.renfe.com/es/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Bordeaux to Santander
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- €19–55
- Website
- https://www.flixbus.co.uk
Bus from Palermo to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 30m
- Frequency
- Twice daily
- Estimated price
- €40–140
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Bordeaux
- Ave. Duration
- 17h 10m
- Frequency
- Once daily
- Estimated price
- €55–100
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Palermo to Florence Villa Constanza Bus Station
- Ave. Duration
- 15h
- Frequency
- Once a week
- Estimated price
- €50–75
- Schedules at
- autoservizisalemi.it
Bus from Palermo Via Tommaso Fazello to Milano, San Donato M3
- Ave. Duration
- 19h 10m
- Frequency
- Once a week
- Estimated price
- €55–85
- Schedules at
- autoservizisalemi.it
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Barcelona, Estació d'Autobusos Nord to Santander E.A.
- Ave. Duration
- 9h 30m
- Frequency
- 3 times a day
- Estimated price
- €65–120
- Website
- https://www.alsa.com/en/
Bus from Bilbao Intermodal to Santander E.A.
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–15
- Website
- https://www.alsa.com/en/
Bus from Vitoria-Gasteiz to Santander E.A.
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- €13
- Website
- https://www.alsa.com/en/
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Milano, Autostazione Lampugnano to Vitoria Gasteiz Central Bus Station
- Ave. Duration
- 23h 30m
- Frequency
- Once a week
- Estimated price
- €60–95
- Website
- https://union-ivkoni.com/en
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €65–140
- Website
- https://www.gnv.it/en
Ferry from Port of Palermo to Port of Civitavecchia
- Ave. Duration
- 12h
- Frequency
- Once a week
- Estimated price
- €55–75
- Website
- https://www.gnv.it/en
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Port of Civitavecchia to Port de Barcelona
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- €55–95
- Website
- https://www.grimaldi-lines.com/en/
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