There are 8 ways to get from Palermo to Santander by plane, car ferry, car, train, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Santander Airport
best- Fly from Palermo Airport (PMO) to Santander Airport (SDR)plane PMO - SDR
7h 19m€74–426Fly to Bilbao Airport, bus
cheapest- Fly from Palermo Airport (PMO) to Bilbao Airport (BIO)plane PMO - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 12m€73–253Car ferry, drive
- Take the carferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Santandercar
33h 9m€293–442Train, bus
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Genova P.Za Principetrain Fa / ...
- Take the bus from Genoa to Marseillebus
- Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain
- Take the train from Madrid Chamartín to Santandertrain Ic / ...
39h 40m€369–717Bus
- Take the bus from Palermo to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Bordeauxbus
- Take the bus from Bordeaux to Estación de autobuses de Santanderbus
42h 35m€239–398Ferry, car ferry, train
- Take the ferry from Palermo to Civitavecchiaferry
- Take the carferry from Port of Civitavecchia to Port de Barcelonacarferry
- Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain Ave
- Take the train from Madrid Chamartín to Santandertrain Ic / ...
43h 51m€261–508Ferry, car ferry, train, bus
- Take the ferry from Palermo to Civitavecchiaferry
- Take the carferry from Port of Civitavecchia to Port de Barcelonacarferry
- Take the train from Barcelona-Paseo De Gracia to Zaragoza-Deliciastrain Re
- Take the train from Zaragoza-Delicias to Miranda De Ebrotrain Ic / ...
- Take the bus from Miranda De Ebro to Estación de autobuses de Santanderbus
2d 1h€242–406Bus, train
- Take the bus from Palermo Piazza Cairoli to Verona Porta Nuova Stationbus
- Take the train from Verona Porta Nuova to Padovatrain Fr
- Take the bus from Padova to Estación de autobuses de Santanderbus
2d 2h
Palermo to Santander by train and bus
Questions & Answers
The cheapest way to get from Palermo to Santander is to fly which costs €70 - €430 and takes 7h 19m.
The fastest way to get from Palermo to Santander is to fly which takes 7h 19m and costs €70 - €430.
No, there is no direct bus from Palermo to Santander. However, there are services departing from Palermo and arriving at Estación de autobuses de Santander via Florence Villa Constanza Bus Station and Bordeaux. The journey, including transfers, takes approximately 42h 35m.
The distance between Palermo and Santander is 1567 km.
The best way to get from Palermo to Santander without a car is to train and bus which takes 39h 40m and costs €360 - €750.
It takes approximately 7h 19m to get from Palermo to Santander, including transfers.
Palermo to Santander bus services, operated by FlixBus, depart from Palermo station.
The best way to get from Palermo to Santander is to fly which takes 7h 19m and costs €70 - €430. Alternatively, you can bus, which costs €230 - €400 and takes 42h 35m.
Palermo to Santander bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Book your Palermo to Santander bus tickets online with Omio and FlixBus.
What companies run services between Palermo, Italy and Santander, Spain?
Ryanair and Ulendo Airlink fly from Palermo Airport (PMO) to Santander Airport (SDR) 6 times a week. Alternatively, you can take a bus from Palermo to Estación de autobuses de Santander via Florence Villa Constanza Bus Station and Bordeaux in around 42h 35m.
- Website
- ryanair.com
Flights from Palermo Airport to Santander Airport via Bologna
- Ave. Duration
- 5h 15m
- When
- Sunday and Thursday
- Estimated price
- €85–320
- Website
- flyulendo.com
Flights from Palermo Airport to Santander Airport via Milan Malpensa
- Ave. Duration
- 7h 2m
- When
- Tuesday and Saturday
- Estimated price
- €70–320
- Website
- volotea.com
Flights from Palermo Airport to Bilbao Airport
- Ave. Duration
- 2h 30m
- When
- Tuesday and Saturday
- Estimated price
- €60–85
- Website
- vueling.com
Flights from Palermo Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 20m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €75–190
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 19m
- Frequency
- 4 times a day
- Estimated price
- €90–190
- Website
- Trenitalia Intercity
Train from Roma Termini to Genova P.Za Principe
- Ave. Duration
- 6h 41m
- Frequency
- Every 4 hours
- Estimated price
- €50–110
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Roma Termini to Genova P.Za Principe
- Ave. Duration
- 4h 47m
- Frequency
- Hourly
- Estimated price
- €70–150
- Schedules at
- Trenitalia Frecce
Train from Verona Porta Nuova to Padova
- Ave. Duration
- 44 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–24
- Schedules at
- Trenitalia Frecce
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 7h 48m
- Frequency
- Twice daily
- Estimated price
- €140–230
- Website
- Renfe Viajeros
Train from Madrid Chamartín to Santander
- Ave. Duration
- 4h 23m
- Frequency
- Every 4 hours
- Estimated price
- €55–85
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 2m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- Renfe Viajeros
Train from Madrid Chamartín to Santander
- Ave. Duration
- 4h 23m
- Frequency
- Every 4 hours
- Estimated price
- €55–85
- Website
- Renfe Viajeros
Train from Barcelona-Paseo De Gracia to Zaragoza-Delicias
- Ave. Duration
- 6h 1m
- Frequency
- 4 times a day
- Estimated price
- €40–70
- Website
- Renfe Viajeros
Train from Zaragoza-Delicias to Miranda De Ebro
- Ave. Duration
- 3h 12m
- Frequency
- Hourly
- Estimated price
- €35–60
- Website
- Renfe Viajeros
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €90–170
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- atencion.cliente@iryo.eu
- Website
- Iryo
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 19m
- Frequency
- Hourly
- Estimated price
- €60–120
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 17m
- Frequency
- Every 2 hours
- Estimated price
- €55–95
- Website
- Ouigo
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Verona Porta Nuova to Padova
- Ave. Duration
- 43 min
- Frequency
- Hourly
- Estimated price
- €10–21
- Website
- Italo Treno
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Verona Porta Nuova to Padova
- Ave. Duration
- 1h 27m
- Frequency
- Every 20 minutes
- Estimated price
- €10–17
- Website
- Trenitalia
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- Trenitalia Eurocity
Train from Verona Porta Nuova to Padova
- Ave. Duration
- 44 min
- Frequency
- 4 times a week
- Estimated price
- €25–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €25–35
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Genoa to Marseille
- Ave. Duration
- 7h 35m
- Frequency
- Every 4 hours
- Estimated price
- €30–60
- Website
- Flixbus
Bus from Palermo to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 20m
- Frequency
- Twice daily
- Estimated price
- €100–170
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Bordeaux
- Ave. Duration
- 17h 10m
- Frequency
- Once daily
- Estimated price
- €100–170
- Website
- Flixbus
Bus from Bordeaux to Estación de autobuses de Santander
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €35–60
- Website
- Flixbus
- Phone
- +34 910 207 007
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- ALSA
Bus from Miranda De Ebro to Estación de autobuses de Santander
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- €15–24
- Website
- ALSA
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Palermo Piazza Cairoli to Verona Porta Nuova Station
- Ave. Duration
- 23h 57m
- Frequency
- Once a week
- Website
- Onebus
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Padova to Estación de autobuses de Santander
- Ave. Duration
- 24h 34m
- Frequency
- 3 times a week
- Estimated price
- €120–150
- Schedules at
- tabitatour.ro
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- Grandi Navi Veloci
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Grandi Navi Veloci
Ferry from Palermo to Civitavecchia
- Ave. Duration
- 13h 45m
- Frequency
- 3 times a week
- Estimated price
- €45–90
- Website
- Grandi Navi Veloci
Car ferry from Port of Civitavecchia to Port de Barcelona
- Ave. Duration
- 19h 30m
- Frequency
- Once a week
- Estimated price
- €100–160
- Website
- Grandi Navi Veloci
Ferry from Palermo to Civitavecchia
- Ave. Duration
- 13h 45m
- Frequency
- 3 times a week
- Estimated price
- €45–90
- Website
- Grandi Navi Veloci
Car ferry from Port of Civitavecchia to Port de Barcelona
- Ave. Duration
- 19h 30m
- Frequency
- Once a week
- Estimated price
- €100–160
- Website
- Grandi Navi Veloci
Want to know more about travelling around Spain
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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