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How to get fromPalermo to Santanderby plane, car ferry, car, train, bus, or ferry

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There are 8 ways to get from Palermo to Santander by plane, car ferry, car, train, bus, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Santander Airport

    best
    1. Fly from Palermo Airport (PMO) to Santander Airport (SDR)plane plane PMO - SDR
    8h 4m
    €79–375

  2. Car ferry, drive

    1. Take the carferry from Port of Palermo to Port of Genoacarferry car ferry
    2. Drive from Port of Genoa to Santandercar car
    33h 9m
    €303–444

  3. Train, bus

    1. Take the train from Palermo Centrale to Roma Terminitrain train Ic
    2. Take the train from Roma Termini to Genova P.Za Principetrain train Fa / ...
    3. Take the bus from Genoa to Marseillebus bus
    4. Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain train
    5. Take the train from Madrid Chamartín to Santandertrain train Alv / ...
    38h 57m
    €375–636

  4. Bus

    1. Take the bus from Palermo to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Bordeauxbus bus
    3. Take the bus from Bordeaux to Estación de autobuses de Santanderbus bus
    42h 35m
    €258–396

  5. Fly to Bilbao Airport, bus

    1. Fly from Palermo Airport (PMO) to Bilbao Airport (BIO)plane plane PMO - BIO
    2. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    8h 7m
    €93–441

  6. Car ferry, bus, train

    1. Take the carferry from Port of Palermo to Port of Genoacarferry car ferry
    2. Take the bus from Genoa to Marseillebus bus
    3. Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain train
    4. Take the train from Madrid Chamartín to Santandertrain train Alv / ...
    43h 3m
    €334–491

  7. Ferry, car ferry, train

    1. Take the ferry from Palermo to Civitavecchiaferry ferry
    2. Take the carferry from Port of Civitavecchia to Port de Barcelonacarferry car ferry
    3. Take the train from Barcelona-Sants to Bilbao-Abandotrain train Alv
    4. Take the train from Bilbao to Santandertrain train
    47h 9m
    €243–382

  8. Bus, train

    1. Take the bus from Palermo Piazza Cairoli to Verona Porta Nuova Stationbus bus
    2. Take the train from Verona Porta Nuova to Padovatrain train Fr
    3. Take the bus from Padova to Estación de autobuses de Santanderbus bus
    2d 2h
    €338–451

Palermo to Santander by train and bus

Calendar14Weekly Services
Duration38h 57mAverage Duration
Ticket€375Cheapest Price
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Comparing Your Travel Options

Map of how to get from Palermo to Santander.ExpandLaunch map view
  • Distance: 1,566.6 km
  • Duration: 8h 4m

What companies run services between Palermo, Italy and Santander, Spain?

Ryanair, Vueling Airlines, and four other airlines fly from Palermo Airport (PMO) to Santander Airport (SDR) once daily. Alternatively, you can take a bus from Palermo to Estación de autobuses de Santander via Florence Villa Constanza Bus Station and Bordeaux in around 42h 35m.

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Want to know more about travelling around Spain

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