There are 8 ways to get from Palermo to Santander by plane, car ferry, car, train, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Santander Airport
best- Fly from Palermo Airport (PMO) to Santander Airport (SDR)plane PMO - SDR
8h 29m€84–305Fly to Bilbao Airport, bus
cheapest- Fly from Palermo Airport (PMO) to Bilbao Airport (BIO)plane PMO - BIO
- Take the bus from Bilbao Intermodal to Santander E.A.bus
8h 4m€83–213Car ferry, drive
- Take the car ferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Santandercar
33h€250–410Train, bus
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Milano Centraletrain Fr / ...
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
- Take the train from Lyon Part Dieu to Massy Tgvtrain Tgv
- Take the train from Massy Tgv to Bordeaux St Jeantrain Tgv
- Take the bus from Bordeaux to Santanderbus
34h 30m€250–777Bus via Turin
- Take the bus from Palermo to Turinbus
- Take the bus from Turin Corso Vittorio Emanuele II to San Sebastian Central Bus Stationbus
- Take the bus from San Sebastián / Donostia to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Santander E.A.bus
44h 59m€142–272Car ferry, bus, train
- Take the car ferry from Port of Palermo to Port of Genoacarferry
- Take the bus from Genoa to Marseillebus
- Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain
- Take the train from Madrid Chamartín to Santandertrain Alv / ...
42h 22m€214–402Ferry, train, bus
- Take the ferry from Port of Palermo to Port of Civitavecchiaferry
- Take the ferry from Port of Civitavecchia to Port de Barcelonaferry
- Take the train from Barcelona-Sants to Bilbao-Abandotrain Alv
- Take the bus from Bilbao Intermodal to Santander E.A.bus
44h 8m€158–285Bus
- Take the bus from Palermo Terminal Bus to Napoli, Autostazione Metroparkbus
- Take the bus from Naples - Bus Station to Barcelona - North Bus Stationbus
- Take the bus from Barcelona, Estació d'Autobusos Nord to Santander E.A.bus
45h 50m€164–346
Palermo to Santander by train, foot, and bus
Questions & Answers
The cheapest way to get from Palermo to Santander is to fly and bus which costs €80 - €220 and takes 8h 4m.
The fastest way to get from Palermo to Santander is to fly and bus which takes 8h 4m and costs €80 - €220.
No, there is no direct bus from Palermo to Santander. However, there are services departing from Palermo and arriving at Santander E.A. via Turin Corso Vittorio Emanuele II, San Sebastián / Donostia and Bilbao Intermodal. The journey, including transfers, takes approximately 44h 59m.
The distance between Palermo and Santander is 1567 km.
The best way to get from Palermo to Santander without a car is to train and bus which takes 34h 30m and costs €250 - €800.
It takes approximately 8h 29m to get from Palermo to Santander, including transfers.
Palermo to Santander bus services, operated by FlixBus, depart from Palermo station.
The best way to get from Palermo to Santander is to fly which takes 8h 29m and costs €80 - €310. Alternatively, you can bus via Turin, which costs €140 - €280 and takes 44h 59m.
Palermo to Santander bus services, operated by FlixBus, arrive at Turin station.
Book your Palermo to Santander bus tickets online with Omio.
What companies run services between Palermo, Italy and Santander, Spain?
Ryanair, Iberia, and Vueling Airlines fly from Palermo Airport (PMO) to Santander Airport (SDR) twice daily. Alternatively, you can take a bus from Palermo to Santander E.A. via Turin, Turin Corso Vittorio Emanuele II, San Sebastian Central Bus Station, San Sebastián / Donostia, and Bilbao Intermodal in around 44h 59m.
- Website
- iberia.com
Flights from Palermo Airport to Santander Airport via Madrid
- Ave. Duration
- 9h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €80–330
Flights from Palermo Airport to Santander Airport via Barcelona
- Ave. Duration
- 6h 40m
- When
- Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- €80–300
Flights from Palermo Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 5h 15m
- When
- Monday, Tuesday, and Thursday
- Estimated price
- €70–190
- Website
- vueling.com
Flights from Palermo Airport to Santander Airport via Madrid
- Ave. Duration
- 8h 35m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €80–310
Flights from Palermo Airport to Santander Airport via Barcelona
- Ave. Duration
- 6h 40m
- When
- Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- €80–300
Flights from Palermo Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 5h 15m
- When
- Monday, Tuesday, and Thursday
- Estimated price
- €70–190
- Website
- volotea.com
Flights from Palermo Airport to Bilbao Airport
- Ave. Duration
- 2h 30m
- When
- Saturday
- Estimated price
- €35–180
Flights from Palermo Airport to Bilbao Airport via Naples
- Ave. Duration
- 4h 25m
- When
- Tuesday
- Estimated price
- €35–180
- Website
- ryanair.com
Flights from Palermo Airport to Santander Airport via Charleroi
- Ave. Duration
- 11h 10m
- When
- Saturday
- Estimated price
- €90–330
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 29m
- Frequency
- Once daily
- Estimated price
- €35–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 8m
- Frequency
- Every 30 minutes
- Estimated price
- €45–110
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- €45–120
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 39m
- Frequency
- Twice daily
- Estimated price
- €50–140
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Lyon Part Dieu to Massy Tgv
- Ave. Duration
- 2h 1m
- Frequency
- Every 4 hours
- Estimated price
- €50–150
- Website
- https://www.sncf-connect.com/en-en
Train from Massy Tgv to Bordeaux St Jean
- Ave. Duration
- 2h 57m
- Frequency
- Every 4 hours
- Estimated price
- €45–190
- Website
- https://www.sncf-connect.com/en-en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Lyon Part Dieu to Massy Tgv
- Ave. Duration
- 2h 3m
- Frequency
- Every 4 hours
- Estimated price
- €70–160
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €70–110
- Rail 1st Class
- €110–160
Train from Massy Tgv to Bordeaux St Jean
- Ave. Duration
- 3h 3m
- Frequency
- Once daily
- Estimated price
- €90–200
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €90–130
- Rail 1st Class
- €130–200
- Phone
- +33 2 22 55 00 10
- nomad-car@laregionnormandie.fr
- Website
- nomad.normandie.fr
Train from Lyon Part Dieu to Massy Tgv
- Ave. Duration
- 2h 7m
- Frequency
- 5 times a week
- Schedules at
- nomad.normandie.fr
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 7h 48m
- Frequency
- Once daily
- Estimated price
- €90–130
- Website
- https://www.renfe.com/es/en
Train from Madrid Chamartín to Santander
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- €40–95
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Bilbao-Abando
- Ave. Duration
- 7h 3m
- Frequency
- Once daily
- Estimated price
- €40–95
- Website
- https://www.renfe.com/es/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Bordeaux to Santander
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €25–55
- Website
- https://www.flixbus.co.uk
Bus from Palermo to Turin
- Ave. Duration
- 24h 15m
- Frequency
- Once daily
- Estimated price
- €80–180
- Website
- https://www.flixbus.co.uk
Bus from San Sebastián / Donostia to Bilbao Intermodal
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- €10–15
- Website
- https://www.flixbus.co.uk
Bus from Genoa to Marseille
- Ave. Duration
- 6h
- Frequency
- 5 times a day
- Estimated price
- €22–55
- Website
- https://www.flixbus.co.uk
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Turin Corso Vittorio Emanuele II to San Sebastian Central Bus Station
- Ave. Duration
- 16h
- Frequency
- Twice a week
- Estimated price
- €40–65
- Website
- https://union-ivkoni.com/en
Bus from San Sebastián / Donostia to Bilbao Intermodal
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €11–17
- Website
- https://gipuzkoa.avanzagrupo.com/en/home
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Bilbao Intermodal to Santander E.A.
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–15
- Website
- https://www.alsa.com/en/
Bus from Barcelona, Estació d'Autobusos Nord to Santander E.A.
- Ave. Duration
- 9h 30m
- Frequency
- 3 times a day
- Estimated price
- €65–120
- Website
- https://www.alsa.com/en/
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Palermo Terminal Bus to Napoli, Autostazione Metropark
- Ave. Duration
- 10h 40m
- Frequency
- 3 times a week
- Estimated price
- €19–27
- Website
- https://www.itabus.it/en/home
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Naples - Bus Station to Barcelona - North Bus Station
- Ave. Duration
- 23h 40m
- Frequency
- Twice daily
- Estimated price
- €80–200
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €60–120
- Website
- https://www.gnv.it/en
Ferry from Port of Palermo to Port of Civitavecchia
- Ave. Duration
- 12h
- Frequency
- Once a week
- Estimated price
- €60–75
- Website
- https://www.gnv.it/en
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Port of Civitavecchia to Port de Barcelona
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- €45–95
- Website
- https://www.grimaldi-lines.com/en/
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