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How to get fromPalermo to Mainzby plane, train, ferry, car ferry, car, bus, or train (Trenitalia)

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There are 10 ways to get from Palermo to Mainz by plane, train, ferry, car ferry, car, bus, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Palermo Airport to Frankfurt

    best
    1. Fly from Palermo Airport (PMO) to Frankfurt (FRA)plane plane PMO - FRA
    5h 38m
    €83–238

  2. Train, ferry

    1. Take the train from Palermo Centrale to Messina Centraletrain train Re
    2. Take the ferry from Messina Marittima to Villa S.Giovanniferry ferry M1 / ...
    3. Take the train from Villa S.Giovanni to Milano Centraletrain train Fr
    4. Take the train from Milano Centrale to Mannheim Hbftrain train Ec
    5. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train S5 / ...
    22h 47m

  3. Car ferry, drive

    1. Take the carferry from Port of Palermo to Port of Genoacarferry car ferry
    2. Drive from Port of Genoa to Mainzcar car
    27h 1m
    €243–364

  4. Bus

    1. Take the bus from Palermo Piazza Cairoli to Mühlheim am Mainbus bus
    30h 59m
    €258–356

  5. Bus to Catania–Fontanarossa Airport, fly to Frankfurt

    1. Take the bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminalbus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Frankfurt (FRA)plane plane CTA - FRA
    7h 34m
    €96–260

  6. Fly Palermo Airport to Stuttgart Airport, train

    1. Fly from Palermo Airport (PMO) to Stuttgart Airport (STR)plane plane PMO - STR
    2. Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train
    8h 7m
    €105–324

  7. Fly Palermo Airport to Hahn, bus

    1. Fly from Palermo Airport (PMO) to Hahn (HHN)plane plane PMO - HHN
    2. Take the bus from Hahn to Mainz, Hauptbahnhofbus bus
    7h 15m
    €103–401

  8. Train

    1. Take the train from Palermo Centrale to Roma Terminitrain train Ic
    2. Take the train from Roma Termini to Milano Centraletrain train
    3. Take the train from Milano Centrale to Basel Sbbtrain train Ec
    4. Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain train 12 / ...
    5. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train S5 / ...
    24h 9m
    €288–540

  9. Bus via Milan

    1. Take the bus from Palermo to Milano, Autostazione Lampugnanobus bus N597
    2. Take the bus from Milan to Mainz central train stationbus bus FlixBus 476
    35h 35m
    €207–308

  10. Bus #2

    1. Take the bus from Palermo Piazza Cairoli to Wiesbaden Gartenfeldstraße P+Rbus bus
    37h 18m
    €294–397

Palermo Airport (PMO) to Frankfurt (FRA) flights

Calendar9Weekly Planes
Duration3h 55mAverage Duration
Ticket€97Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Palermo to Mainz.ExpandLaunch map view
  • Distance: 1,424.6 km
  • Duration: 5h 38m

What companies run services between Palermo, Italy and Mainz, Germany?

Lufthansa and ITA Airways fly from Palermo Airport (PMO) to Frankfurt (FRA) once daily. Alternatively, Onebus operates a bus from Palermo Piazza Cairoli to Mühlheim am Main once a week. Tickets cost €250–350 and the journey takes 28h 18m.

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Want to know more about travelling around Germany

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