There are 10 ways to get from Palermo to Mainz by plane, train, ferry, car ferry, car, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Palermo Airport to Frankfurt
best- Fly from Palermo Airport (PMO) to Frankfurt (FRA)PMO - FRA
5h 43m€96–238Fly Palermo Airport to Hahn, bus
cheapest- Fly from Palermo Airport (PMO) to Hahn (HHN)PMO - HHN
- Take the bus from Frankfurt Hahn Airport to Mainz Short-term parking lot Am Schlag
7h 19m€86–315Train, ferry
- Take the train from Palermo Centrale to Messina CentraleRe
- Take the ferry from Messina Marittima to Villa S.GiovanniM1 / ...
- Take the train from Villa S.Giovanni to Milano CentraleFr
- Take the train from Milano Centrale to Mannheim HbfEc
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS5 / ...
22h 49mCar ferry, drive
- Take the car ferry from Port of Palermo to Port of Genoa
- Drive from Port of Genoa to Mainz
28h 14m€180–300Bus, train
- Take the bus from Palermo Via Tommaso Fazello to Milano, San Donato M3
- Take the bus from Milan to Mannheim Central Bus Station
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS5 / ...
33h 22m€117–158Bus to Catania–Fontanarossa Airport, fly to Frankfurt
- Take the bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminal
- Fly from Catania–Fontanarossa Airport (CTA) to Frankfurt (FRA)CTA - FRA
7h 39m€108–312Fly Palermo Airport to Cologne Bonn Airport, train
- Fly from Palermo Airport (PMO) to Cologne Bonn Airport (CGN)PMO - CGN
- Take the train from Siegburg Bf to Frankfurt
7h 24m€108–395Train
- Take the train from Palermo Centrale to Roma TerminiIc
- Take the train from Roma Termini to Milano CentraleFr / ...
- Take the train from Milano Centrale to Mannheim HbfEc
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS5 / ...
24h 13m€204–422Car ferry, train
- Take the car ferry from Port of Palermo to Port of Genoa
- Take the train from Genova P.Za Principe to Milano CentraleIc
- Take the train from Milano Centrale to Mannheim HbfEc
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS5 / ...
32h 37m€174–325Bus
- Take the bus from Palermo to Milano, Autostazione LampugnanoN597
- Take the bus from Milano, Autostazione Lampugnano to Mainz central train station476
35h 30m€90–255
Palermo Airport (PMO) to Frankfurt (FRA) flights
Questions & Answers
The cheapest way to get from Palermo to Mainz is to fly and bus which costs €85 - €320 and takes 7h 19m.
The fastest way to get from Palermo to Mainz is to fly which takes 5h 43m and costs €95 - €240.
No, there is no direct bus from Palermo to Mainz station. However, there are services departing from Palermo and arriving at Mainz central train station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 35h 30m.
No, there is no direct train from Palermo to Mainz. However, there are services departing from Palermo Centrale and arriving at Mainz, Römisches Theater via Roma Termini, Milano Centrale and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 24h 13m.
The distance between Palermo and Mainz is 1425 km.
The best way to get from Palermo to Mainz without a car is to train and ferry which takes 22h 49m and costs .
It takes approximately 5h 43m to get from Palermo to Mainz, including transfers.
Palermo to Mainz bus services, operated by FlixBus, depart from Palermo station.
Palermo to Mainz train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Palermo to Mainz is to fly which takes 5h 43m and costs €95 - €240. Alternatively, you can train, which costs €200 - €430 and takes 24h 13m, you could also bus, which costs €90 - €260 and takes 35h 30m.
What companies run services between Palermo, Italy and Mainz, Germany?
Lufthansa, ITA Airways, and Air Dolomiti fly from Palermo Airport (PMO) to Frankfurt (FRA) 4 times a day. Alternatively, you can take a train from Palermo Centrale to Mainz, Römisches Theater via Roma Termini, Milano Centrale, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 24h 13m.
- Website
- ita-airways.com
Flights from Palermo Airport to Frankfurt via Munich
- Ave. Duration
- 3h 50m
- When
- Friday to Sunday
- Estimated price
- €120–380
Flights from Palermo Airport to Frankfurt via Milan Linate
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- €80–220
Flights from Catania–Fontanarossa Airport to Frankfurt
- Ave. Duration
- 2h 35m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €170–340
Flights from Catania–Fontanarossa Airport to Frankfurt via Milan Linate
- Ave. Duration
- 4h 26m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–200
Flights from Catania–Fontanarossa Airport to Frankfurt via Munich
- Ave. Duration
- 4h 30m
- When
- Friday to Sunday
- Estimated price
- €170–340
- Website
- lufthansa.com
Flights from Palermo Airport to Frankfurt
- Ave. Duration
- 2h 25m
- When
- Saturday
- Estimated price
- €120–380
Flights from Palermo Airport to Frankfurt via Munich
- Ave. Duration
- 4h 50m
- When
- Friday to Sunday
- Estimated price
- €120–380
Flights from Catania–Fontanarossa Airport to Frankfurt
- Ave. Duration
- 2h 35m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €170–340
Flights from Catania–Fontanarossa Airport to Frankfurt via Munich
- Ave. Duration
- 4h 30m
- When
- Friday to Sunday
- Estimated price
- €170–340
Flights from Palermo Airport to Cologne Bonn Airport via Munich
- Ave. Duration
- 5h
- When
- Saturday and Sunday
- Estimated price
- €100–410
- Website
- ryanair.com
Flights from Palermo Airport to Hahn
- Ave. Duration
- 2h 20m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €65–290
Flights from Palermo Airport to Hahn via Rome
- Ave. Duration
- 4h
- When
- Saturday
- Estimated price
- €65–290
Flights from Palermo Airport to Hahn via Milan Bergamo
- Ave. Duration
- 4h 30m
- When
- Saturday
- Estimated price
- €65–290
Flights from Palermo Airport to Cologne Bonn Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Wednesday, Friday, and Saturday
- Estimated price
- €60–260
Flights from Palermo Airport to Cologne Bonn Airport via Bologna
- Ave. Duration
- 4h 20m
- When
- Thursday
- Estimated price
- €60–260
- Website
- swiss.com
Flights from Catania–Fontanarossa Airport to Frankfurt via Zurich
- Ave. Duration
- 4h 45m
- When
- Thursday and Friday
- Estimated price
- €190–440
- Website
- eurowings.com
Flights from Palermo Airport to Cologne Bonn Airport
- Ave. Duration
- 2h 25m
- When
- Tuesday
- Estimated price
- €110–290
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 56m
- Frequency
- Every 4 hours
- Estimated price
- €13–20
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Milano Centrale
- Ave. Duration
- 1h 56m
- Frequency
- Every 3 hours
- Estimated price
- €12–25
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- €17–26
- Website
- https://www.trenitalia.com/en.html
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 17h 31m
- Frequency
- 3 times a week
- Estimated price
- €70–140
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 29m
- Frequency
- Once daily
- Estimated price
- €35–110
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 7h 25m
- Frequency
- Once a week
- Estimated price
- €35–75
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Milano Centrale
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- €14–22
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 8h 17m
- Frequency
- 5 times a day
- Estimated price
- €95–200
- Schedules at
- trenitalia.com
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 8m
- Frequency
- Every 30 minutes
- Estimated price
- €45–110
- Schedules at
- trenitalia.com
Train from Genova P.Za Principe to Milano Centrale
- Ave. Duration
- 1h 46m
- Frequency
- Twice daily
- Estimated price
- €16–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 9h 40m
- Frequency
- Twice daily
- Estimated price
- €75–180
- Website
- https://www.italotreno.it/en
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- €45–120
- Website
- https://www.italotreno.it/en
Train from Genova P.Za Principe to Milano Centrale
- Ave. Duration
- 1h 51m
- Frequency
- Once daily
- Estimated price
- €11–28
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 6 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Siegburg Bf to Frankfurt
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- €25–65
- Website
- https://int.bahn.de/en
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Palermo Via Tommaso Fazello to Milano, San Donato M3
- Ave. Duration
- 19h 10m
- Frequency
- Once a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
Bus from Palermo to Milano, Autostazione Lampugnano
- Ave. Duration
- 19h 50m
- Frequency
- Once a week
- Estimated price
- €50–75
- Schedules at
- autoservizisalemi.it
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Milan to Mannheim Central Bus Station
- Ave. Duration
- 11h 35m
- Frequency
- Twice a week
- Estimated price
- €55–70
- Website
- https://marinobus.it/en/
- info@flibco.com
- Website
- flibco.com
Bus from Frankfurt Hahn Airport to Mainz Short-term parking lot Am Schlag
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Estimated price
- €17–20
- Website
- https://www.flibco.com/en
- Phone
- 800 21 10 20
- saisautolineeweb@gmail.com
- Website
- saisautolinee.it
Bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminal
- Ave. Duration
- 2h 30m
- Frequency
- Hourly
- Estimated price
- €11–17
- Schedules at
- saisautolinee.it
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminal
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- €11–20
- Website
- https://www.flixbus.co.uk
Bus from Palermo to Milano, Autostazione Lampugnano
- Ave. Duration
- 22h 15m
- Frequency
- Once daily
- Estimated price
- €60–160
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Mainz central train station
- Ave. Duration
- 12h 15m
- Frequency
- Twice daily
- Estimated price
- €40–100
- Website
- https://www.flixbus.co.uk
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €60–120
- Website
- https://www.gnv.it/en
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Travelling by boat in Italy
Read the travel guide
More Questions & Answers
Palermo to Mainz bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.
Palermo to Mainz train services, operated by Trenitalia Intercity, arrive at Roma Termini station.
Book your Palermo to Mainz train tickets online with Omio.
Book your Palermo to Mainz bus tickets online with Omio and FlixBus.
There are 1141+ hotels available in Mainz.


























































