There are 10 ways to get from Palermo to Mainz by plane, train, ferry, car ferry, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Palermo Airport to Frankfurt
best- Fly from Palermo Airport (PMO) to Frankfurt (FRA)plane PMO - FRA
5h 47m€84–219Fly Palermo Airport to Hahn, bus
cheapest- Fly from Palermo Airport (PMO) to Hahn (HHN)plane PMO - HHN
- Take the bus from Hahn to Mainz, Hauptbahnhofbus
7h 15m€68–222Train, ferry
- Take the train from Palermo Centrale to Messina Centraletrain Re
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain 55 / ...
22h 20mCar ferry, drive
- Take the car ferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Mainzcar
28h 16m€223–327Bus
- Take the bus from Palermo Piazza Cairoli to Mühlheim am Mainbus
31h 15mBus to Catania–Fontanarossa Airport, fly to Frankfurt
- Take the bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminalbus
- Fly from Catania–Fontanarossa Airport (CTA) to Frankfurt (FRA)plane CTA - FRA
7h 38m€97–251Fly Palermo Airport to Stuttgart Airport, train
- Fly from Palermo Airport (PMO) to Stuttgart Airport (STR)plane PMO - STR
- Take the train from Hauptbahnhof to Frankfurttrain
7h 44m€107–365Fly Palermo Airport to Cologne Bonn Airport, train
- Fly from Palermo Airport (PMO) to Cologne Bonn Airport (CGN)plane PMO - CGN
- Take the train from Siegburg/Bonn to Frankfurt(M) Flughafen Fernbftrain
7h 14m€92–421Bus via Milan
- Take the bus from Palermo to Milano, Autostazione Lampugnanobus N597
- Take the bus from Milan to Mainz central train stationbus FlixBus 476
35h 35m€191–314Bus #2
- Take the bus from Palermo Piazza Cairoli to Wiesbaden Gartenfeldstraße P+Rbus
37h 27m
Palermo Airport (PMO) to Frankfurt (FRA) flights
Questions & Answers
The cheapest way to get from Palermo to Mainz is to fly and bus which costs €65 - €230 and takes 7h 15m.
The fastest way to get from Palermo to Mainz is to fly which takes 5h 47m and costs €80 - €220.
No, there is no direct bus from Palermo to Mainz. However, there are services departing from Palermo Piazza Cairoli and arriving at Ginsheim-Gustavsburg-Gustavsburg Am Alten Fährhaus via Mühlheim, Obertshausen Bahnhof and Frankfurt. The journey, including transfers, takes approximately 31h 15m.
The distance between Palermo and Mainz is 1425 km.
The best way to get from Palermo to Mainz without a car is to train and ferry which takes 22h 20m and costs .
It takes approximately 5h 47m to get from Palermo to Mainz, including transfers.
Palermo to Mainz bus services, operated by Onebus, depart from Palermo Piazza Cairoli station.
The best way to get from Palermo to Mainz is to fly which takes 5h 47m and costs €80 - €220. Alternatively, you can bus, which costs and takes 31h 15m.
Palermo to Mainz bus services, operated by Onebus, arrive at Mühlheim am Main station.
Book your Palermo to Mainz bus tickets online with Omio.
What companies run services between Palermo, Italy and Mainz, Germany?
Lufthansa, ITA Airways, and Air Dolomiti fly from Palermo Airport (PMO) to Frankfurt (FRA) 5 times a day. Alternatively, Onebus operates a bus from Palermo Piazza Cairoli to Mühlheim am Main once a week, and the journey takes 28h 18m.
- Website
- lufthansa.com
Flights from Palermo Airport to Frankfurt
- Ave. Duration
- 2h 30m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €75–270
Flights from Palermo Airport to Frankfurt via Munich
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €75–270
Flights from Catania–Fontanarossa Airport to Frankfurt
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- €75–270
Flights from Catania–Fontanarossa Airport to Frankfurt via Munich
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- €55–270
Flights from Palermo Airport to Stuttgart Airport via Munich
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- €95–330
- Website
- ita-airways.com
Flights from Palermo Airport to Frankfurt via Milan Linate
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- €90–190
Flights from Palermo Airport to Frankfurt via Munich
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €75–270
Flights from Catania–Fontanarossa Airport to Frankfurt
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- €75–270
Flights from Catania–Fontanarossa Airport to Frankfurt via Milan Linate
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- €85–160
- Website
- eurowings.com
Flights from Palermo Airport to Stuttgart Airport
- Ave. Duration
- 2h 5m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €75–210
Flights from Palermo Airport to Cologne Bonn Airport
- Ave. Duration
- 2h 25m
- When
- Tuesday, Thursday, Friday, and Saturday
- Estimated price
- €100–220
- Website
- swiss.com
Flights from Palermo Airport to Stuttgart Airport via Zurich
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €90–310
- Website
- ryanair.com
Flights from Palermo Airport to Hahn
- Ave. Duration
- 2h 20m
- When
- Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- €50–200
Flights from Palermo Airport to Cologne Bonn Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- €65–210
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 3h 2m
- Frequency
- Every 2 hours
- Estimated price
- €27–45
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- €23–50
- Website
- https://www.trenitalia.com/en.html
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 15h 13m
- Frequency
- Twice a week
- Estimated price
- €120–260
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 8h 47m
- Frequency
- Every 4 hours
- Estimated price
- €170–350
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 10h 28m
- Frequency
- Twice daily
- Estimated price
- €150–300
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- Twice daily
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- €12–55
- Website
- https://int.bahn.de/en
Train from Hauptbahnhof to Frankfurt
- Ave. Duration
- 1h 12m
- Frequency
- Hourly
- Estimated price
- €30–140
- Website
- https://int.bahn.de/en
Train from Siegburg/Bonn to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- €26–110
- Website
- https://int.bahn.de/en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €13–21
- Website
- https://int.bahn.de/en
- Phone
- +49 621 830 1200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 52 min
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Hauptbahnhof to Frankfurt
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €20–40
- Website
- https://www.ns.nl/en
Train from Siegburg/Bonn to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- €16–35
- Website
- https://www.ns.nl/en
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- onebus.it
Bus from Palermo Piazza Cairoli to Mühlheim am Main
- Ave. Duration
- 28h 18m
- Frequency
- Once a week
- Website
- https://onebus.it/
Bus from Palermo Piazza Cairoli to Wiesbaden Gartenfeldstraße P+R
- Ave. Duration
- 36h 55m
- Frequency
- Once a week
- Website
- https://onebus.it/
- Phone
- 800 21 10 20
- saisautolineeweb@gmail.com
- Website
- saisautolinee.it
Bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminal
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Estimated price
- €11–17
- Schedules at
- saisautolinee.it
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminal
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- €17–28
- Website
- https://www.flixbus.co.uk
Bus from Palermo to Milano, Autostazione Lampugnano
- Ave. Duration
- 22h 20m
- Frequency
- Once daily
- Estimated price
- €130–220
- Website
- https://www.flixbus.co.uk
Bus from Milan to Mainz central train station
- Ave. Duration
- 12h 15m
- Frequency
- Once daily
- Estimated price
- €60–100
- Website
- https://www.flixbus.co.uk
- Phone
- +49 (0) 6543 5019-400
- reisebuero@bohr.de
- Website
- bohr.de
Bus from Hahn to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €14–16
- Schedules at
- bohr.de
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- https://www.gnv.it/en
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