There are 9 ways to get from Palermo to Mainz by plane, train, ferry, car ferry, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Palermo Airport to Frankfurt
best- Fly from Palermo Airport (PMO) to Frankfurt (FRA)plane PMO - FRA
5h 47m€89–269Fly Palermo Airport to Hahn, bus
cheapest- Fly from Palermo Airport (PMO) to Hahn (HHN)plane PMO - HHN
- Take the bus from Frankfurt Hahn Airport to Mainz Short-term parking lot Am Schlagbus
7h 10m€77–256Train, ferry
- Take the train from Palermo Centrale to Messina Centraletrain Re
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain 55 / ...
22h 50mCar ferry, drive
- Take the car ferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Mainzcar
28h 16m€217–330Bus
- Take the bus from Palermo to Milano, Autostazione Lampugnanobus N597
- Take the bus from Milan to Mainz central train stationbus FlixBus 476
35h 35m€117–282Bus to Catania–Fontanarossa Airport, fly to Frankfurt
- Take the bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminalbus
- Fly from Catania–Fontanarossa Airport (CTA) to Frankfurt (FRA)plane CTA - FRA
7h 38m€92–268Fly Palermo Airport to Stuttgart Airport, train
- Fly from Palermo Airport (PMO) to Stuttgart Airport (STR)plane PMO - STR
- Take the train from Hauptbahnhof to Frankfurttrain
7h 45m€106–365Car ferry, train
- Take the car ferry from Port of Palermo to Port of Genoacarferry
- Take the train from Genova P.Za Principe to Milano Centraletrain
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
32h 40m€244–380Bus, train
- Take the bus from Palermo to Agrigentobus
- Take the bus from Agrigento Piazzale Rosselli to Stuttgart Airportbus
- Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain 47 / ...
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
36h 13m
Palermo Airport (PMO) to Frankfurt (FRA) flights
Questions & Answers
The cheapest way to get from Palermo to Mainz is to fly and bus which costs €75 - €260 and takes 7h 10m.
The fastest way to get from Palermo to Mainz is to fly which takes 5h 47m and costs €85 - €270.
No, there is no direct bus from Palermo to Mainz station. However, there are services departing from Palermo and arriving at Mainz central train station via Milan. The journey, including transfers, takes approximately 35h 35m.
The distance between Palermo and Mainz is 1425 km.
The best way to get from Palermo to Mainz without a car is to train and ferry which takes 22h 50m and costs .
It takes approximately 5h 47m to get from Palermo to Mainz, including transfers.
Palermo to Mainz bus services, operated by FlixBus, depart from Palermo station.
The best way to get from Palermo to Mainz is to fly which takes 5h 47m and costs €85 - €270. Alternatively, you can bus, which costs €110 - €290 and takes 35h 35m.
Palermo to Mainz bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.
Book your Palermo to Mainz bus tickets online with Omio and FlixBus.
What companies run services between Palermo, Italy and Mainz, Germany?
Lufthansa, ITA Airways, and Air Dolomiti fly from Palermo Airport (PMO) to Frankfurt (FRA) 5 times a day. Alternatively, you can take a bus from Palermo to Mainz central train station via Milan in around 35h 35m.
- Website
- lufthansa.com
Flights from Palermo Airport to Frankfurt
- Ave. Duration
- 2h 30m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €80–310
Flights from Palermo Airport to Frankfurt via Munich
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €80–310
Flights from Catania–Fontanarossa Airport to Frankfurt
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- €80–300
Flights from Catania–Fontanarossa Airport to Frankfurt via Munich
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- €55–300
Flights from Palermo Airport to Stuttgart Airport via Munich
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- €100–390
- Website
- ita-airways.com
Flights from Palermo Airport to Frankfurt via Munich
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €80–310
Flights from Palermo Airport to Frankfurt via Milan Linate
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- €90–230
Flights from Catania–Fontanarossa Airport to Frankfurt
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- €80–300
Flights from Catania–Fontanarossa Airport to Frankfurt via Milan Linate
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- €85–270
- Website
- swiss.com
Flights from Palermo Airport to Stuttgart Airport via Zurich
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €95–350
- Website
- eurowings.com
Flights from Palermo Airport to Stuttgart Airport
- Ave. Duration
- 2h 5m
- When
- Monday, Wednesday, and Saturday
- Estimated price
- €75–210
- Website
- ryanair.com
Flights from Palermo Airport to Hahn
- Ave. Duration
- 2h 20m
- When
- Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- €55–210
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 48m
- Frequency
- Hourly
- Estimated price
- €27–45
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Milano Centrale
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €17–28
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 3h
- Frequency
- Every 4 hours
- Estimated price
- €23–50
- Website
- https://www.trenitalia.com/en.html
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 15h 13m
- Frequency
- 5 times a week
- Estimated price
- €120–270
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Milano Centrale
- Ave. Duration
- 2h 33m
- Frequency
- Hourly
- Estimated price
- €14–35
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 9h 34m
- Frequency
- Every 3 hours
- Estimated price
- €180–350
- Schedules at
- trenitalia.com
Train from Genova P.Za Principe to Milano Centrale
- Ave. Duration
- 1h 37m
- Frequency
- 5 times a day
- Estimated price
- €20–40
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 10h 28m
- Frequency
- Twice daily
- Estimated price
- €150–290
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- 3 times a day
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- 3 times a day
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 2 hours
- Estimated price
- €13–45
- Website
- https://int.bahn.de/en
Train from Hauptbahnhof to Frankfurt
- Ave. Duration
- 1h 12m
- Frequency
- Hourly
- Estimated price
- €30–110
- Website
- https://int.bahn.de/en
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Every 30 minutes
- Estimated price
- €19–65
- Website
- https://int.bahn.de/en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €14–20
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €13–20
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €13–20
- Website
- https://int.bahn.de/en
- Phone
- +49 621 830 1200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 52 min
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Schedules at
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 6 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 6 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Hauptbahnhof to Frankfurt
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €19–45
- Website
- https://www.ns.nl/en
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Once daily
- Estimated price
- €11–26
- Website
- https://www.ns.nl/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Palermo to Milano, Autostazione Lampugnano
- Ave. Duration
- 22h 20m
- Frequency
- Once daily
- Estimated price
- €110–200
- Website
- https://www.flixbus.co.uk
Bus from Milan to Mainz central train station
- Ave. Duration
- 12h 15m
- Frequency
- Once daily
- Estimated price
- €55–90
- Website
- https://www.flixbus.co.uk
Bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminal
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- €15–25
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Palermo to Milano, Autostazione Lampugnano
- Ave. Duration
- 19h 50m
- Frequency
- Once a week
- Estimated price
- €60–90
- Schedules at
- autoservizisalemi.it
- Phone
- 800 21 10 20
- saisautolineeweb@gmail.com
- Website
- saisautolinee.it
Bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminal
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Estimated price
- €11–17
- Schedules at
- saisautolinee.it
- info@flibco.com
- Website
- flibco.com
Bus from Frankfurt Hahn Airport to Mainz Short-term parking lot Am Schlag
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €17–40
- Website
- https://www.flibco.com/en
- Phone
- +39 091 616 15 10
- info@cuffaro.info
- Website
- cuffaro.info
Bus from Palermo to Agrigento
- Ave. Duration
- 2h
- Frequency
- Every 4 hours
- Estimated price
- €9
- Schedules at
- cuffaro.info
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- onebus.it
Bus from Agrigento Piazzale Rosselli to Stuttgart Airport
- Ave. Duration
- 30h
- Frequency
- Once a week
- Website
- https://onebus.it/
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €95–140
- Website
- https://www.gnv.it/en
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €95–140
- Website
- https://www.gnv.it/en
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