There are 10 ways to get from Palermo to Lucerne by plane, train, train (Trenitalia), car ferry, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Zurich Airport, train
best- Fly from Palermo Airport (PMO) to Zurich Airport (ZRH)plane PMO - ZRH
- Take the train from Zürich HB to Luzerntrain
6h 1mCHF 94–223Fly to Milano Malpensa Airport, train
cheapest- Fly from Palermo Airport (PMO) to Milano Malpensa Airport (MXP)plane PMO - MXP
- Take the train from Malpensa Aeroporto T1 to Luganotrain
- Take the train from Lugano to Luzerntrain
8h 18mCHF 73–342Train
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Milano Centraletrain
- Take the train from Milano Centrale to Luganotrain
- Take the train from Lugano to Luzerntrain Ec
19h 11mCHF 207–363Car ferry, drive
- Take the carferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Lucernecar
24h 43mCHF 156–228Bus
- Take the bus from Palermo Piazza Cairoli to ZÜRICH, Carparkplatz am Sihlquaibus
- Take the bus from Zürich Hbf to Luzern, Bahnhofbus
26h 26mCHF 214–291Fly to Basel, train
- Fly from Palermo Airport (PMO) to Basel (BSL)plane PMO - BSL
- Take the train from Basel SBB to Luzerntrain
6h 56mCHF 79–261Fly to Milan Linate Airport, train
- Fly from Palermo Airport (PMO) to Milan Linate Airport (LIN)plane PMO - LIN
- Take the train from Monza to Luganotrain
- Take the train from Lugano to Luzerntrain
8h 29mCHF 109–295Fly to Il Caravaggio International Airport, bus, train
- Fly from Palermo Airport (PMO) to Il Caravaggio International Airport (BGY)plane PMO - BGY
- Take the bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoiabus
- Take the train from Milano Centrale to Luganotrain
- Take the train from Lugano to Luzerntrain
8h 56mCHF 93–323Bus via Milan
- Take the bus from Palermo to Milano, Autostazione Lampugnanobus N597
- Take the bus from Milan to Luzernbus FlixBus 1524 / ...
27h 30mCHF 144–221Car ferry, train
- Take the carferry from Port of Palermo to Port of Genoacarferry
- Take the train from Genova P.Za Principe to Arth-Goldautrain Ec
27h 40mCHF 174–267
Palermo to Lucerne by train
Comparing Your Travel Options
The cheapest way to get from Palermo to Lucerne is to fly and train which costs SFr 75 - SFr 270 and takes 6h 56m.
The fastest way to get from Palermo to Lucerne is to fly and train which takes 6h 1m and costs SFr 90 - SFr 230.
No, there is no direct bus from Palermo to Lucerne. However, there are services departing from Palermo Piazza Cairoli and arriving at Luzern, Bahnhof via Zürich Hbf. The journey, including transfers, takes approximately 26h 26m.
No, there is no direct train from Palermo to Lucerne. However, there are services departing from Palermo Centrale and arriving at Luzern via Roma Termini, Milano Centrale and Lugano. The journey, including transfers, takes approximately 19h 11m.
The distance between Palermo and Lucerne is 1190 km.
The best way to get from Palermo to Lucerne without a car is to train which takes 19h 11m and costs SFr 200 - SFr 370.
It takes approximately 6h 1m to get from Palermo to Lucerne, including transfers.
Palermo to Lucerne bus services, operated by Onebus, depart from Palermo Piazza Cairoli station.
Palermo to Lucerne train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Palermo to Lucerne is to train which takes 19h 11m and costs SFr 200 - SFr 370. Alternatively, you can bus, which costs SFr 210 - SFr 300 and takes 26h 26m.
What companies run services between Palermo, Italy and Lucerne, Switzerland?
You can take a train from Palermo Centrale to Luzern via Roma Termini, Milano Centrale, and Lugano in around 19h 11m. Alternatively, you can take a bus from Palermo Piazza Cairoli to Luzern, Bahnhof via ZÜRICH, Carparkplatz am Sihlquai and Zürich Hbf in around 26h 26m.
- Website
- ryanair.com
Flights from Palermo Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- CHF 35–120
Flights from Palermo Airport to Milano Malpensa Airport via Cagliari
- Ave. Duration
- 3h 35m
- When
- Sunday and Tuesday
- Estimated price
- CHF 35–120
Flights from Palermo Airport to Il Caravaggio International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- CHF 25–170
Flights from Palermo Airport to Il Caravaggio International Airport via Cagliari
- Ave. Duration
- 4h 20m
- When
- Monday and Sunday
- Estimated price
- CHF 25–170
- Website
- easyjet.com
Flights from Palermo Airport to Basel
- Ave. Duration
- 2h 10m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- CHF 35–170
Flights from Palermo Airport to Basel via Nice
- Ave. Duration
- 4h 15m
- When
- Tuesday
- Estimated price
- CHF 35–170
Flights from Palermo Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- CHF 30–270
- Website
- ita-airways.com
Flights from Palermo Airport to Milan Linate Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- CHF 40–140
Flights from Palermo Airport to Milan Linate Airport via Rome
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- CHF 40–140
- Website
- swiss.com
Flights from Palermo Airport to Zurich Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- CHF 85–340
- Website
- flyulendo.com
Flights from Palermo Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- CHF 9–210
- Website
- lufthansa.com
Flights from Palermo Airport to Basel via Munich
- Ave. Duration
- 4h 20m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- CHF 110–410
Flights from Palermo Airport to Milan Linate Airport via Rome
- Ave. Duration
- 4h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 40–140
Train from Zürich HB to Luzern
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 18–30
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Luzern
- Ave. Duration
- 1h 39m
- Frequency
- Every 3 hours
- Estimated price
- CHF 55–90
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 2 hours
- Estimated price
- CHF 30–50
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Luzern
- Ave. Duration
- 1h 39m
- Frequency
- Every 3 hours
- Estimated price
- CHF 55–90
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Luzern
- Ave. Duration
- 1h 39m
- Frequency
- Every 3 hours
- Estimated price
- CHF 55–90
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Luzern
- Ave. Duration
- 1h 39m
- Frequency
- Every 3 hours
- Estimated price
- CHF 55–90
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 19m
- Frequency
- Twice daily
- Estimated price
- CHF 85–160
- Website
- Trenitalia Intercity
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- CHF 60–110
- Website
- Italo Treno
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- Trenord
Train from Milano Centrale to Lugano
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- CHF 5–7
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Lugano
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- CHF 5–7
- Website
- Trenord
Train from Monza to Lugano
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- CHF 3–5
- Website
- Trenord
Train from Milano Centrale to Lugano
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- CHF 5–7
- Website
- Trenord
- Phone
- +41 58 580 70 70
- Website
- Schweizerische Südostbahn AG
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 4 hours
- Estimated price
- CHF 30–45
- Schedules at
- Schweizerische Südostbahn AG
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- Trenitalia Eurocity
Train from Genova P.Za Principe to Arth-Goldau
- Ave. Duration
- 4h 54m
- Frequency
- Once daily
- Estimated price
- CHF 70–120
- Website
- Trenitalia Eurocity
- 1st Class
- CHF 80–120
- 2nd Class
- CHF 70–95
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Palermo Piazza Cairoli to ZÜRICH, Carparkplatz am Sihlquai
- Ave. Duration
- 24h 42m
- Frequency
- Once a week
- Estimated price
- CHF 210–290
- Website
- Onebus
- Phone
- + 381 31 510 060
- zlatanprevoz@gmail.com
- Website
- facebook.com
Bus from Zürich Hbf to Luzern, Bahnhof
- Ave. Duration
- 36 min
- Frequency
- Once a week
- Estimated price
- CHF 1–3
- Schedules at
- facebook.com
- customerservices@terravision.eu
- Website
- TERRAVISION
Bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoia
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 4–21
- Website
- TERRAVISION
- Phone
- 035.319366
- ticket@orioshuttle.com
- Website
- orioshuttle.com
Bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoia
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 10–13
- Schedules at
- orioshuttle.com
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Palermo to Milano, Autostazione Lampugnano
- Ave. Duration
- 22h 20m
- Frequency
- Once daily
- Estimated price
- CHF 130–200
- Website
- Flixbus
Bus from Milan to Luzern
- Ave. Duration
- 4h 10m
- Frequency
- 4 times a day
- Estimated price
- CHF 19–30
- Website
- Flixbus
- Phone
- +420 222 222 221
- info@regiojet.com
- Website
- RegioJet
Bus from Milan to Luzern
- Ave. Duration
- 3h 40m
- Frequency
- Twice a week
- Estimated price
- CHF 14–23
- Website
- RegioJet
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- Grandi Navi Veloci
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- CHF 95–140
- Website
- Grandi Navi Veloci
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- CHF 95–140
- Website
- Grandi Navi Veloci
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Palermo to Lucerne bus services, operated by Onebus, arrive at ZÜRICH, Carparkplatz am Sihlquai station.
Palermo to Lucerne train services, operated by Trenitalia Intercity, arrive at Roma Termini station.
Book your Palermo to Lucerne train tickets online with Omio.
Book your Palermo to Lucerne bus tickets online with Omio.
There are 663+ hotels available in Lucerne.

















































