There are 9 ways to get from Palermo to Heidelberg by plane, train, ferry, car ferry, car, bus, night train, shuttle, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Palermo Airport to Frankfurt, train
best- Fly from Palermo Airport (PMO) to Frankfurt (FRA)plane PMO - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
6h 25m€108–337Shuttle to Trapani Airport, fly to Karlsruhe/Baden-Baden Airport, train
cheapest- Take a shuttle bus from Lazio Municipio to Trapani Birgi Airport
- Fly from Trapani Airport (TPS) to Karlsruhe/Baden-Baden Airport (FKB)plane TPS - FKB
- Take the train from Karlsruhe Hauptbahnhof to Heidelberg, Hauptbahnhoftrain
8h 1m€95–600Train, ferry
- Take the train from Palermo Centrale to Messina Centraletrain Re
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
21h 48mCar ferry, drive
- Take the car ferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Heidelbergcar
27h 40m€172–320Bus, train, night train
- Take the bus from Palermo Via Tommaso Fazello to Milano, San Donato M3bus
- Take the train from Milano Centrale to Zuerich Hbtrain Ec
- Take the night train from Zuerich Hb to Heidelberg Hbfnighttrain Nj
28h 58m€150–455Fly Palermo Airport to Stuttgart Airport, train
- Fly from Palermo Airport (PMO) to Stuttgart Airport (STR)plane PMO - STR
- Take the train from Hauptbahnhof to Heidelberg, Hauptbahnhoftrain
6h 39m€120–318Train
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Milano Centraletrain Fr / ...
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
23h 4m€283–555Car ferry, train
- Take the car ferry from Port of Palermo to Port of Genoacarferry
- Take the train from Genova P.Za Principe to Milano Centraletrain Ic
- Take the train from Milano Centrale to Karlsruhe Hbftrain Ec
- Take the train from Karlsruhe Hauptbahnhof to Heidelberg, Hauptbahnhoftrain S3 / ...
31h 25m€172–372Bus
- Take the bus from Palermo to Milano, Autostazione Lampugnanobus N597
- Take the bus from Milan to Heidelberg Pre Waypointbus FlixBus N07 / ...
32h 24m€97–233
Palermo Airport (PMO) to Frankfurt (FRA) flights
Questions & Answers
The cheapest way to get from Palermo to Heidelberg is to bus which costs €95 - €240 and takes 32h 24m.
The fastest way to get from Palermo to Heidelberg is to fly and train which takes 6h 25m and costs €100 - €340.
No, there is no direct bus from Palermo to Heidelberg. However, there are services departing from Palermo and arriving at Heidelberg Pre Waypoint via Milan. The journey, including transfers, takes approximately 32h 24m.
No, there is no direct train from Palermo to Heidelberg. However, there are services departing from Palermo Centrale and arriving at Heidelberg, Hauptbahnhof via Roma Termini, Milano Centrale and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 23h 4m.
The distance between Palermo and Heidelberg is 1488 km.
The best way to get from Palermo to Heidelberg without a car is to train and ferry which takes 21h 48m and costs .
It takes approximately 6h 25m to get from Palermo to Heidelberg, including transfers.
Palermo to Heidelberg bus services, operated by FlixBus, depart from Palermo station.
Palermo to Heidelberg train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Palermo to Heidelberg is to train which takes 23h 4m and costs €280 - €600. Alternatively, you can bus, which costs €95 - €240 and takes 32h 24m.
What companies run services between Palermo, Italy and Heidelberg, Germany?
You can take a train from Palermo Centrale to Heidelberg, Hauptbahnhof via Roma Termini, Milano Centrale, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 23h 4m. Alternatively, you can take a bus from Palermo to Heidelberg Pre Waypoint via Milan in around 32h 24m.
- Website
- lufthansa.com
Flights from Palermo Airport to Frankfurt
- Ave. Duration
- 2h 25m
- When
- Thursday and Saturday
- Estimated price
- €75–310
Flights from Palermo Airport to Frankfurt via Munich
- Ave. Duration
- 3h 50m
- When
- Friday to Sunday
- Estimated price
- €75–310
Flights from Palermo Airport to Stuttgart Airport via Munich
- Ave. Duration
- 4h 20m
- When
- Friday and Sunday
- Estimated price
- €95–550
- Website
- ita-airways.com
Flights from Palermo Airport to Frankfurt via Munich
- Ave. Duration
- 3h 50m
- When
- Friday to Sunday
- Estimated price
- €75–310
Flights from Palermo Airport to Frankfurt via Milan Linate
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- €80–270
- Website
- eurowings.com
Flights from Palermo Airport to Stuttgart Airport
- Ave. Duration
- 2h 5m
- When
- Wednesday
- Estimated price
- €85–220
- Website
- ryanair.com
Flights from Trapani Airport to Karlsruhe/Baden-Baden Airport
- Ave. Duration
- 2h 5m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €65–600
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €26–30
- Website
- https://int.bahn.de/en
Train from Hauptbahnhof to Heidelberg, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- €29–32
- Website
- https://int.bahn.de/en
Train from Karlsruhe Hauptbahnhof to Heidelberg, Hauptbahnhof
- Ave. Duration
- 42 min
- Frequency
- 5 times a day
- Estimated price
- €24–27
- Website
- https://int.bahn.de/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- 4 times a day
- Estimated price
- €12–40
- Website
- https://www.ns.nl/en
- 2nd Class
- €12–19
- 1st Class
- €23–40
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 45m
- Frequency
- Every 4 hours
- Estimated price
- €13–20
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Milano Centrale
- Ave. Duration
- 1h 53m
- Frequency
- Every 4 hours
- Estimated price
- €9–14
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- €21–50
- Website
- https://www.trenitalia.com/en.html
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 15h 13m
- Frequency
- Twice a week
- Estimated price
- €110–270
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 34m
- Frequency
- Once daily
- Estimated price
- €85–200
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Milano Centrale
- Ave. Duration
- 1h 36m
- Frequency
- Hourly
- Estimated price
- €13–35
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 8h 43m
- Frequency
- 4 times a day
- Estimated price
- €170–340
- Schedules at
- trenitalia.com
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 8m
- Frequency
- Every 30 minutes
- Estimated price
- €80–160
- Schedules at
- trenitalia.com
Train from Genova P.Za Principe to Milano Centrale
- Ave. Duration
- 1h 41m
- Frequency
- Twice daily
- Estimated price
- €20–40
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 9h 33m
- Frequency
- Twice daily
- Estimated price
- €130–180
- Website
- https://www.italotreno.it/en
- Smart Economy
- €130–170
- Smart Flex
- €140–180
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 40m
- Frequency
- Every 2 hours
- Estimated price
- €70–95
- Website
- https://www.italotreno.it/en
- Smart Economy
- €70–95
- Smart Flex
- €75–95
Train from Genova P.Za Principe to Milano Centrale
- Ave. Duration
- 1h 51m
- Frequency
- Once daily
- Estimated price
- €30–45
- Website
- https://www.italotreno.it/en
- Smart Economy
- €30–45
- Smart Flex
- €30–45
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
Train from Milano Centrale to Zuerich Hb
- Ave. Duration
- 3h 17m
- Frequency
- Every 2 hours
- Estimated price
- €55–110
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €70–110
- 2nd Class
- €55–75
Train from Milano Centrale to Karlsruhe Hbf
- Ave. Duration
- 6h 19m
- Frequency
- Once daily
- Estimated price
- €80–140
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €80–120
- 2nd Class
- €100–140
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Zuerich Hb to Heidelberg Hbf
- Ave. Duration
- 4h 2m
- Frequency
- Once daily
- Estimated price
- €35–260
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €259–260
- Couchette Carriage
- €130–160
- Seating Carriage
- €35–50
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Karlsruhe Hauptbahnhof to Heidelberg, Hauptbahnhof
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €11–17
- Website
- https://int.bahn.de/en
- Phone
- +43 5 1717
- Website
- konzern.oebb.at
Train from Karlsruhe Hauptbahnhof to Heidelberg, Hauptbahnhof
- Ave. Duration
- 42 min
- Frequency
- Twice daily
- Estimated price
- €17–26
- Website
- https://konzern.oebb.at/en/
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Palermo Via Tommaso Fazello to Milano, San Donato M3
- Ave. Duration
- 19h 10m
- Frequency
- Once a week
- Estimated price
- €55–85
- Schedules at
- autoservizisalemi.it
Bus from Palermo to Milano, Autostazione Lampugnano
- Ave. Duration
- 19h 50m
- Frequency
- Once a week
- Estimated price
- €60–90
- Schedules at
- autoservizisalemi.it
- customerservices@terravision.eu
- Website
- terravision.eu
Shuttle from Lazio Municipio to Trapani Birgi Airport
- Ave. Duration
- 1h 39m
- Frequency
- Every 4 hours
- Estimated price
- €11
- Website
- https://www.terravision.eu/
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Palermo to Milano, Autostazione Lampugnano
- Ave. Duration
- 22h 30m
- Frequency
- Once daily
- Estimated price
- €95–170
- Website
- https://www.flixbus.co.uk
Bus from Milan to Heidelberg Pre Waypoint
- Ave. Duration
- 8h 54m
- Frequency
- 4 times a day
- Estimated price
- €35–65
- Website
- https://www.flixbus.co.uk
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €70–160
- Website
- https://www.gnv.it/en
- Seat
- €70–110
- Cabin
- €130–160
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Travelling by boat in Italy
Read the travel guide
More Questions & Answers
Palermo to Heidelberg bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.
Palermo to Heidelberg train services, operated by Trenitalia Intercity, arrive at Roma Termini station.
Book your Palermo to Heidelberg bus tickets online with Omio and FlixBus.
There are 1198+ hotels available in Heidelberg.































































