There are 11 ways to get from Padova to Isernia by train (Trenitalia), bus, car, plane, train, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Padova to Roma Tiburtinatrain 8911 / ...
- Take the train from Roma Tiburtina to Iserniatrain Re
6h 32m€79–139Fly Venice Marco Polo Airport to Naples Airport, train
cheapest- Fly from Venice Marco Polo Airport (VCE) to Naples Airport (NAP)plane VCE - NAP
- Take the train from Caserta to Iserniatrain
6h 47m€30–178Bus
- Take the bus from Padua Via Fra' Paolo Sarpi to Rome Tiburtina Largo Mazzonibus Itabus
- Take the bus from Roma, Autostazione Tiburtina to Iserniabus Rome Tiburtina
9h 25m€34–68Drive 610.5 km
- Drive from Padova to Iserniacar 610.5 km
6h 10m€99–143Train via Rome (Trenitalia)
- Take the train from Padova to Roma Terminitrain Fr
- Take the train from Roma Termini to Iserniatrain Re
6h 37m€73–145Bus via Pesaro
- Take the bus from Padua to Pesarobus N433
- Take the bus from Pesaro to Iserniabus 433
11h 39m€51–81Fly Venice Marco Polo Airport to Fiumicino International Airport, train
- Fly from Venice Marco Polo Airport (VCE) to Fiumicino International Airport (FCO)plane VCE - FCO
- Take the train from Roma Termini to Iserniatrain
6h 42m€84–240Train to Bologna Guglielmo Marconi Airport, fly to Fiumicino International Airport, train
- Take the train from Padova to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Fiumicino International Airport (FCO)plane BLQ - FCO
- Take the train from Roma Termini to Iserniatrain
7h€88–249Train to Verona Villafranca Airport, fly to Fiumicino International Airport, train
- Take the train from Padova to Verona Porta Nuovatrain
- Fly from Verona Villafranca Airport (VRN) to Fiumicino International Airport (FCO)plane VRN - FCO
- Take the train from Roma Termini to Iserniatrain
7h 8m€106–315Train to Trieste – Friuli Venezia Giulia Airport, fly to Naples Airport, train
- Take the train from Padova to Trieste Airporttrain
- Fly from Trieste – Friuli Venezia Giulia Airport (TRS) to Naples Airport (NAP)plane TRS - NAP
- Take the train from Caserta to Iserniatrain
7h 37m€72–242Shuttle to Il Caravaggio International Airport, fly to Abruzzo Airport, bus
- Take a shuttle bus from Padova to Orio al Serio Airport
- Fly from Il Caravaggio International Airport (BGY) to Abruzzo Airport (PSR)plane BGY - PSR
- Take the bus from Pescara Airport to San Salvo Marinabus
- Take the bus from San Salvo Marina to Iserniabus
8h 57m€280–651
Padova to Isernia by train
Comparing Your Travel Options
The cheapest way to get from Padova to Isernia is to bus which costs €30 - €70 and takes 9h 25m.
The fastest way to get from Padova to Isernia is to drive which takes 6h 10m and costs €95 - €150.
No, there is no direct bus from Padova to Isernia. However, there are services departing from Padua Via Fra' Paolo Sarpi and arriving at Isernia via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 9h 25m.
No, there is no direct train from Padova to Isernia. However, there are services departing from Padova and arriving at Isernia via Roma Tiburtina. The journey, including transfers, takes approximately 6h 32m.
The distance between Padova and Isernia is 655 km. The road distance is 610.5 km.
The best way to get from Padova to Isernia without a car is to train which takes 6h 32m and costs €75 - €140.
It takes approximately 6h 32m to get from Padova to Isernia, including transfers.
Padova to Isernia bus services, operated by Itabus S.p.A., depart from Padua Via Fra' Paolo Sarpi station.
Padova to Isernia train services, operated by ItaloTreno, depart from Padova station.
The best way to get from Padova to Isernia is to train which takes 6h 32m and costs €75 - €140. Alternatively, you can bus, which costs €30 - €70 and takes 9h 25m.
What companies run services between Padova, Italy and Isernia, Italy?
You can take a train from Padova to Isernia via Roma Tiburtina in around 6h 32m. Alternatively, you can take a bus from Padua Via Fra' Paolo Sarpi to Isernia via Roma, Autostazione Tiburtina in around 9h 25m.
- Website
- ryanair.com
Flights from Venice Marco Polo Airport to Naples Airport
- Ave. Duration
- 1h 15m
- When
- Wednesday to Saturday
- Estimated price
- €30–140
Flights from Trieste – Friuli Venezia Giulia Airport to Naples Airport
- Ave. Duration
- 1h 15m
- When
- Monday to Tuesday
- Estimated price
- €40–200
Flights from Il Caravaggio International Airport to Abruzzo Airport
- Ave. Duration
- 1h 10m
- When
- Sunday, Friday, Monday, Thursday, and Saturday
- Estimated price
- €40–230
- Website
- ita-airways.com
Flights from Venice Marco Polo Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 3h 10m
- When
- Monday to Saturday
- Estimated price
- €75–150
Flights from Venice Marco Polo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- €70–190
Flights from Bologna Guglielmo Marconi Airport to Fiumicino International Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €55–140
Flights from Verona Villafranca Airport to Fiumicino International Airport
- Ave. Duration
- 1h 10m
- When
- Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- €55–210
Flights from Trieste – Friuli Venezia Giulia Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 3h 12m
- When
- Monday to Saturday
- Estimated price
- €75–170
- Website
- volotea.com
Flights from Venice Marco Polo Airport to Naples Airport
- Ave. Duration
- 1h 20m
- When
- Sunday
- Estimated price
- €11–120
Flights from Venice Marco Polo Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 3h
- When
- Monday to Saturday
- Estimated price
- €75–150
Flights from Venice Marco Polo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- €70–190
Flights from Bologna Guglielmo Marconi Airport to Fiumicino International Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €55–140
Flights from Trieste – Friuli Venezia Giulia Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 3h
- When
- Monday to Saturday
- Estimated price
- €75–170
- Website
- flyulendo.com
Flights from Venice Marco Polo Airport to Naples Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €12–120
Flights from Trieste – Friuli Venezia Giulia Airport to Naples Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €19–160
- Website
- neosair.it
Flights from Verona Villafranca Airport to Fiumicino International Airport
- Ave. Duration
- 1h 13m
- When
- Friday, Saturday, and Monday
- Estimated price
- €160–420
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Padova to Roma Tiburtina
- Ave. Duration
- 3h 18m
- Frequency
- Hourly
- Estimated price
- €55–95
- Website
- Italo Treno
Train from Padova to Bologna Centrale
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €14–24
- Website
- Italo Treno
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- €9–16
- Website
- Italo Treno
Train from Padova to Trieste Airport
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- €17–28
- Website
- Italo Treno
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Padova to Roma Tiburtina
- Ave. Duration
- 3h 1m
- Frequency
- Every 4 hours
- Estimated price
- €65–110
- Website
- Trenitalia Frecce
Train from Padova to Roma Termini
- Ave. Duration
- 3h 29m
- Frequency
- Hourly
- Estimated price
- €65–110
- Website
- Trenitalia Frecce
Train from Padova to Bologna Centrale
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- €17–29
- Website
- Trenitalia Frecce
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- Every 30 minutes
- Estimated price
- €11–19
- Website
- Trenitalia Frecce
Train from Padova to Trieste Airport
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- €19–35
- Website
- Trenitalia Frecce
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Roma Tiburtina to Isernia
- Ave. Duration
- 2h 14m
- Frequency
- Twice daily
- Estimated price
- €22–30
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- Every 3 hours
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Padova to Bologna Centrale
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €14–20
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- €9–14
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- Every 3 hours
- Estimated price
- €10–15
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Padova to Roma Termini
- Ave. Duration
- 6h 30m
- Frequency
- 4 times a day
- Estimated price
- €50–95
- Website
- Trenitalia Intercity
Train from Padova to Bologna Centrale
- Ave. Duration
- 1h 31m
- Frequency
- 4 times a day
- Estimated price
- €13–24
- Website
- Trenitalia Intercity
Train from Padova to Trieste Airport
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- €15–28
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- Trenitalia Eurocity
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- 3 times a day
- Estimated price
- €25–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €25–35
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Padua Via Fra' Paolo Sarpi to Rome Tiburtina Largo Mazzoni
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- €26–45
- Website
- Itabus S.p.A.
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Bus from San Salvo Marina to Isernia
- Ave. Duration
- 1h 12m
- Frequency
- Once a week
- Estimated price
- €4–6
- Schedules at
- atm-molise.it
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €15–23
- Website
- Flixbus
Bus from Padua to Pesaro
- Ave. Duration
- 4h 40m
- Frequency
- 5 times a week
- Estimated price
- €20–35
- Website
- Flixbus
Bus from Pesaro to Isernia
- Ave. Duration
- 5h 59m
- Frequency
- Once daily
- Estimated price
- €30–50
- Website
- Flixbus
- Phone
- +386 1 320 4530
- info@goopti.com
- Website
- GoOpti
Shuttle from Padova to Orio al Serio Airport
- Ave. Duration
- 2h 12m
- Frequency
- On demand
- Estimated price
- €230–390
- Website
- GoOpti
- Phone
- 0865.221788
- info@satiautobus.com
- Website
- satiautobus.com
Bus from Pescara Airport to San Salvo Marina
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- €3–5
- Schedules at
- satiautobus.com
Want to know more about travelling around Italy
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Booking & Getting There
Padova to Isernia bus services, operated by Itabus S.p.A., arrive at Rome Tiburtina Largo Mazzoni station.
Padova to Isernia train services, operated by ItaloTreno, arrive at Roma Tiburtina station.
Yes, the driving distance between Padova to Isernia is 611 km. It takes approximately 6h 10m to drive from Padova to Isernia.
Book your Padova to Isernia train tickets online with Omio.
Book your Padova to Isernia bus tickets online with Omio.
There are 459+ hotels available in Isernia.









































