Rome2Rio

How to get fromOtranto to Palermoby bus, train, ferry, car or plane

Find Transport to Palermo

See all options

There are 8 ways to get from Otranto to Palermo by bus, train, ferry, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Messina

    best
    1. Take the bus from Otranto, Via Orte to Messina - Piazza della Repubblicabus bus
    2. Take the bus from Messina Piazza della Repubblica to Palermo Via Oretobus bus Sais Autolinee 8863 / ...
    13h
    €51–67
  2. Bus, train

    cheapest
    1. Take the bus from Otranto - Stazione FSE to Lecce - Viale Gallipolibus bus 101 / ...
    2. Take the train from Lecce to Lamezia Terme C.train train Ic
    3. Take the train from Lamezia Terme C. to Palermo Centraletrain train Ic
    15h
    €36–141
  3. Bus, train, ferry

    1. Take the bus from Otranto to Lecce - Via Don Boscobus bus 790
    2. Take the train from Lecce to Lamezia Terme C.train train Ic
    3. Take the train from Lamezia Terme C. to Villa S.Giovannitrain train Re
    4. Take the ferry from Villa S.Giovanni to Messina Marittimaferry ferry V1 / ...
    5. Take the train from Messina Centrale to Palermo Centraletrain train Re
    13h 23m
  4. Drive, ferry

    1. Drive from Otranto to Villa San Giovannicar car
    2. Take the ferry from Villa San Giovanni to Messina Marittimaferry ferry
    3. Drive from Messina Marittima to Palermocar car
    9h 17m
    €112–166
  5. Bus, train to Naples Airport, fly

    1. Take the bus from Otranto to Lecce - Via Don Boscobus bus
    2. Take the train from Lecce to Casertatrain train
    3. Fly from Naples Airport (NAP) to Palermo Airport (PMO)plane plane NAP - PMO
    11h 1m
    €57–190
  6. Bus

    1. Take the bus from Otranto - Stazione FSE to Lecce - City Terminalbus bus 101 / ...
    2. Take the bus from Lecce to Palermobus bus N595
    15h 12m
    €48–94
  7. Bus, train, bus to Bari Karol Wojtyła Airport, fly

    1. Take the bus from Otranto to Lecce - Via Don Boscobus bus
    2. Take the train from Lecce to Bari Centraletrain train
    3. Take the bus from Bari to Altamurabus bus
    4. Take the bus from Altamura Via Matera to Bari Airportbus bus
    5. Fly from Bari Karol Wojtyła Airport (BRI) to Palermo Airport (PMO)plane plane BRI - PMO
    10h 51m
    €79–185
  8. Bus, train to Brindisi Airport, fly

    1. Take the bus from Otranto to Lecce - Via Don Boscobus bus
    2. Take the train from Lecce to Brindisitrain train
    3. Fly from Brindisi Airport (BDS) to Palermo Airport (PMO)plane plane BDS - PMO
    6h 33m
    €63–198

Otranto to Palermo by bus and foot

Calendar12Weekly Services
Duration13hAverage Duration
Ticket€51Cheapest Price
See schedules

Questions & Answers

What companies run services between Otranto, Apulia, Italy and Palermo, Italy?

You can take a bus from Otranto, Via Orte to John Lennon 100 via Messina - Piazza della Repubblica, Messina Piazza della Repubblica, Palermo Via Oreto, and Regione Siciliana Oreto in around 13h.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides