There are 8 ways to get from Otranto to Palermo by bus, train, ferry, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Messina
best- Take the bus from Otranto, Via Orte to Messina - Piazza della Repubblicabus
- Take the bus from Messina Piazza della Repubblica to Palermo Via Oretobus Sais Autolinee 8863 / ...
13h€51–67Bus, train
cheapest- Take the bus from Otranto - Stazione FSE to Lecce - Viale Gallipolibus 101 / ...
- Take the train from Lecce to Lamezia Terme C.train Ic
- Take the train from Lamezia Terme C. to Palermo Centraletrain Ic
15h€36–141Bus, train, ferry
- Take the bus from Otranto to Lecce - Via Don Boscobus 790
- Take the train from Lecce to Lamezia Terme C.train Ic
- Take the train from Lamezia Terme C. to Villa S.Giovannitrain Re
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
13h 23mDrive, ferry
- Drive from Otranto to Villa San Giovannicar
- Take the ferry from Villa San Giovanni to Messina Marittimaferry
- Drive from Messina Marittima to Palermocar
9h 17m€112–166Bus, train to Naples Airport, fly
- Take the bus from Otranto to Lecce - Via Don Boscobus
- Take the train from Lecce to Casertatrain
- Fly from Naples Airport (NAP) to Palermo Airport (PMO)plane NAP - PMO
11h 1m€57–190Bus
- Take the bus from Otranto - Stazione FSE to Lecce - City Terminalbus 101 / ...
- Take the bus from Lecce to Palermobus N595
15h 12m€48–94Bus, train, bus to Bari Karol Wojtyła Airport, fly
- Take the bus from Otranto to Lecce - Via Don Boscobus
- Take the train from Lecce to Bari Centraletrain
- Take the bus from Bari to Altamurabus
- Take the bus from Altamura Via Matera to Bari Airportbus
- Fly from Bari Karol Wojtyła Airport (BRI) to Palermo Airport (PMO)plane BRI - PMO
10h 51m€79–185Bus, train to Brindisi Airport, fly
- Take the bus from Otranto to Lecce - Via Don Boscobus
- Take the train from Lecce to Brindisitrain
- Fly from Brindisi Airport (BDS) to Palermo Airport (PMO)plane BDS - PMO
6h 33m€63–198
Otranto to Palermo by bus and foot
Questions & Answers
The cheapest way to get from Otranto to Palermo is to bus via Messina which costs €50 - €70 and takes 13h.
The fastest way to get from Otranto to Palermo is to bus and train and fly which takes 6h 33m and costs €60 - €200.
No, there is no direct bus from Otranto to Palermo. However, there are services departing from Otranto, Via Orte and arriving at John Lennon 100 via Messina Piazza della Repubblica and Regione Siciliana Oreto. The journey, including transfers, takes approximately 13h.
The distance between Otranto and Palermo is 799 km.
The best way to get from Otranto to Palermo without a car is to bus via Messina which takes 13h and costs €50 - €70.
It takes approximately 13h to get from Otranto to Palermo, including transfers.
Otranto to Palermo bus services, operated by SAIS trasporti S.p.A. - Autolinee Giamporcaro, depart from Otranto, Via Orte station.
Otranto to Palermo bus services, operated by SAIS trasporti S.p.A. - Autolinee Giamporcaro, arrive at Messina - Piazza della Repubblica station.
There are 5776+ hotels available in Palermo.
What companies run services between Otranto, Apulia, Italy and Palermo, Italy?
You can take a bus from Otranto, Via Orte to John Lennon 100 via Messina - Piazza della Repubblica, Messina Piazza della Repubblica, Palermo Via Oreto, and Regione Siciliana Oreto in around 13h.
- Website
- ryanair.com
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 1h
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €40–110
Flights from Bari Karol Wojtyła Airport to Palermo Airport
- Ave. Duration
- 1h 5m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €40–130
Flights from Brindisi Airport to Palermo Airport
- Ave. Duration
- 1h 10m
- When
- Tuesday
- Estimated price
- €50–160
- Website
- easyjet.com
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €20–95
- Website
- volotea.com
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 1h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €20–90
- Website
- tuifly.be
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Friday
- Estimated price
- €75–250
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Lecce to Lamezia Terme C.
- Ave. Duration
- 4h 31m
- Frequency
- Twice daily
- Estimated price
- €12–90
- Website
- https://www.trenitalia.com/en.html
Train from Lamezia Terme C. to Villa S.Giovanni
- Ave. Duration
- 2h 31m
- Frequency
- Every 4 hours
- Estimated price
- €11–18
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 8m
- Frequency
- Twice daily
- Estimated price
- €12–26
- Website
- https://www.trenitalia.com/en.html
Train from Lamezia Terme C. to Palermo Centrale
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- €19–45
- Website
- https://www.trenitalia.com/en.html
Train from Lecce to Bari Centrale
- Ave. Duration
- 1h 33m
- Frequency
- 4 times a day
- Estimated price
- €11–18
- Website
- https://www.trenitalia.com/en.html
Train from Lecce to Brindisi
- Ave. Duration
- 20 min
- Frequency
- 4 times a day
- Estimated price
- €9
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lamezia Terme C. to Villa S.Giovanni
- Ave. Duration
- 1h 22m
- Frequency
- Hourly
- Estimated price
- €10–35
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Every 4 hours
- Estimated price
- €17
- Website
- https://www.trenitalia.com/en.html
Train from Lecce to Bari Centrale
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €11–24
- Website
- https://www.trenitalia.com/en.html
Train from Lecce to Brindisi
- Ave. Duration
- 30 min
- Frequency
- Hourly
- Estimated price
- €3–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Lamezia Terme C. to Villa S.Giovanni
- Ave. Duration
- 1h 19m
- Frequency
- Every 4 hours
- Estimated price
- €17–35
- Schedules at
- trenitalia.com
Train from Lecce to Caserta
- Ave. Duration
- 4h 45m
- Frequency
- 4 times a day
- Estimated price
- €30–65
- Schedules at
- trenitalia.com
Train from Lecce to Bari Centrale
- Ave. Duration
- 1h 24m
- Frequency
- Every 2 hours
- Estimated price
- €9–24
- Schedules at
- trenitalia.com
Train from Lecce to Brindisi
- Ave. Duration
- 20 min
- Frequency
- Every 2 hours
- Estimated price
- €16–17
- Schedules at
- trenitalia.com
- Phone
- +39 0912742800
- info@saistrasporti.it
- Website
- saistrasporti.it
Bus from Otranto, Via Orte to Messina - Piazza della Repubblica
- Ave. Duration
- 8h 25m
- Frequency
- Twice daily
- Estimated price
- €35–50
- Website
- https://saistrasporti.it/en-US
- Phone
- 800 21 10 20
- saisautolineeweb@gmail.com
- Website
- saisautolinee.it
Bus from Messina Piazza della Repubblica to Palermo Via Oreto
- Ave. Duration
- 2h 40m
- Frequency
- 5 times a day
- Estimated price
- €12–18
- Schedules at
- saisautolinee.it
- Phone
- 800 07 9090
- Website
- fseonline.it
Bus from Otranto to Lecce - Via Don Bosco
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- €1–4
- Schedules at
- fseonline.it
Bus from Otranto - Stazione FSE to Lecce - Viale Gallipoli
- Ave. Duration
- 1h 37m
- Frequency
- Every 4 hours
- Estimated price
- €2–4
- Schedules at
- provincia.le.it
Bus from Otranto - Stazione FSE to Lecce - City Terminal
- Ave. Duration
- 1h 42m
- Frequency
- Every 4 hours
- Estimated price
- €2–4
- Schedules at
- provincia.le.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Lecce to Palermo
- Ave. Duration
- 12h 30m
- Frequency
- Once daily
- Estimated price
- €45–90
- Website
- https://www.flixbus.co.uk
- Phone
- +39 080 5790211
- info@cotrap.it
- Website
- bari.airports.aeroportidipuglia.it
Bus from Bari to Altamura
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- €5–10
- Schedules at
- bari.airports.aeroportidipuglia.it
- 2nd Class
- €7–10
- Phone
- +39 080 5790111
- info@cotrap.it
- Website
- cotrap.it
Bus from Altamura Via Matera to Bari Airport
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- €6
- Schedules at
- biglietteria.cotrap.it
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- 342 32 55 869
- Website
- blujetlines.it
Ferry from Villa San Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
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