There are 5 ways to get from Otay Mesa to Los Angeles by bus, train, night bus, car, tram or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  4 h 1 min

  1. Take the bus from San Ysidro, Ca to Los Angeles, Ca 9486 / ...

$23 - $50

4 alternative options

Train  •  4 h 54 min

  1. Take the train from San Diego Santa Fe Depot Amtrak to Los Angeles Union Station Amtrak Pacific Surfliner

$35 - $80

Night bus  •  5 h 10 min

  1. Take the night bus from San Diego Santa Fe Depot Amtrak to Los Angeles Union Station Amtrak Amtrak Thruway Connecting Service

Drive  •  2 h 21 min

  1. Drive from Otay Mesa to Los Angeles 135.8 miles

$13 - $20

Line 905 bus, tram, fly  •  3 h 54 min

  1. Take the line 905 bus from Otay Mesa Rd & Heritage Rd to Iris Avenue Transit Center
  2. Take the tram from Iris Ave Station to America Plaza Station
  3. Fly from San Diego (SAN) to Los Angeles (LAX) SAN - LAX

$113 - $356

Questions & Answers

The cheapest way to get from Otay Mesa to Los Angeles is to drive which costs $13 - $20 and takes 2 h 21 min.

More details

The quickest way to get from Otay Mesa to Los Angeles is to drive which costs $13 - $20 and takes 2 h 21 min.

More details

The distance between Otay Mesa and Los Angeles is 126 miles. The road distance is 135.8 miles.

Get driving directions

It takes approximately 4 h 1 min to get from Otay Mesa to Los Angeles, including transfers.

More details

No, there is no direct bus from Otay Mesa to Los Angeles. However, there are services departing from Otay Mesa Rd & Heritage Rd and arriving at Los Angeles, Ca via Iris Avenue Transit Center and San Ysidro, Ca. The journey, including transfers, takes approximately 4 h 1 min.

More details

Yes, the driving distance between Otay Mesa to Los Angeles is 136 miles. It takes approximately 2 h 21 min to drive from Otay Mesa to Los Angeles.

Get driving directions

Map of how to get from Otay Mesa to Los Angeles.
Launch map view
  • Distance: 126 miles
  • Duration: 4 h 1 min

What companies run services between Otay Mesa, CA, USA and Los Angeles, CA, USA?

Greyhound USA operates a bus from Otay Mesa to Los Angeles every 30 minutes. Tickets cost $19 - $45 and the journey takes 3 h. Alternatively, Amtrak operates a train from Otay Mesa to Los Angeles every 2 hours. Tickets cost $30 - $75 and the journey takes 2 h 59 min.

Airlines
United Airlines
Website
united.com
Flights from San Diego to Los Angeles
Ave. Duration
1 h
When
Every day
Estimated price
$110 - $650
Delta
Website
delta.com
Flights from San Diego to Los Angeles
Ave. Duration
1 h 2 min
When
Every day
Estimated price
$140 - $600
American Airlines
Website
aa.com
Flights from San Diego to Los Angeles
Ave. Duration
59 min
When
Every day
Estimated price
$110 - $600
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from San Diego Santa Fe Depot Amtrak to Los Angeles Union Station Amtrak
Ave. Duration
2 h 59 min
Frequency
Every 2 hours
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
San Diego Metro Transit
Phone
+1 619-233-3004
Website
sdmts.com
Tram from Iris Ave Station to America Plaza Station
Ave. Duration
38 min
Frequency
Every 15 minutes
Estimated price
$3
Schedules at
sdmts.com
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from San Ysidro, Ca to Los Angeles, Ca
Ave. Duration
3 h
Frequency
Every 30 minutes
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$35 - $45

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