There are 5 ways to get from Otay Mesa to Los Angeles by bus, train, car, tram or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  4 h

  1. Take the bus from San Ysidro, Ca to Los Angeles, Ca 9486 / ...

$22 - $48

4 alternative options

Amtrak Thruway  •  4 h 39 min

  1. Take the Amtrak Thruway from San Diego, CA to Los Angeles, CA 5818

Train  •  4 h 53 min

  1. Take the train from San Diego Santa Fe Depot Amtrak to Los Angeles Union Station Amtrak Pacific Surfliner

$35 - $80

Drive  •  2 h 21 min

  1. Drive from Otay Mesa to Los Angeles 135.8 miles

$13 - $20

Line 905 bus, tram, fly  •  4 h 3 min

  1. Take the line 905 bus from Otay Mesa Rd & Heritage Rd to Iris Avenue Transit Center
  2. Take the tram from Iris Ave Station to America Plaza Station
  3. Fly from San Diego (SAN) to Los Angeles (LAX) SAN - LAX

$114 - $359

What companies run services between Otay Mesa, CA, USA and Los Angeles, CA, USA?

Greyhound USA operates a bus from Otay Mesa to Los Angeles every 30 minutes. Tickets cost $19 - $45 and the journey takes 3 h. Alternatively, Amtrak operates a train from Otay Mesa to Los Angeles every 2 hours. Tickets cost $30 - $75 and the journey takes 2 h 59 min.

Airlines
United Airlines
Website
united.com
Flights from San Diego to Los Angeles
Ave. Duration
57 min
When
Every day
Estimated price
$110 - $650
American Airlines
Website
aa.com
Flights from San Diego to Los Angeles
Ave. Duration
1 h 3 min
When
Every day
Estimated price
$110 - $600
Delta
Website
delta.com
Flights from San Diego to Los Angeles
Ave. Duration
58 min
When
Every day
Estimated price
$140 - $600
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from San Diego Santa Fe Depot Amtrak to Los Angeles Union Station Amtrak
Ave. Duration
2 h 59 min
Frequency
Every 2 hours
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
San Diego Metro Transit
Website
sdmts.com
Tram from Iris Ave Station to America Plaza Station
Ave. Duration
38 min
Frequency
Every 15 minutes
Estimated price
$3
Schedules at
sdmts.com
Bus operators

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Questions & Answers

How far is it from Otay Mesa to Los Angeles?

The distance between Otay Mesa and Los Angeles is 202 km. The road distance is 217 km.

What is the cheapest way to get from Otay Mesa to Los Angeles?

The cheapest way to get from Otay Mesa to Los Angeles is to drive which costs $13 - $20 and takes 2 h 21 min.

What is the fastest way to get from Otay Mesa to Los Angeles?

The quickest way to get from Otay Mesa to Los Angeles is to drive which takes 2 h 21 min and costs $13 - $20.

Is there a direct bus between Otay Mesa and Los Angeles?

No, there is no direct bus from Otay Mesa to Los Angeles. However, there are services departing from Otay Mesa Rd & Heritage Rd and arriving at Los Angeles, Ca via Iris Avenue Transit Center and San Ysidro, Ca. The journey, including transfers, takes approximately 4 h.

How long does it take to get from Otay Mesa to Los Angeles?

It takes approximately 4 h to get from Otay Mesa to Los Angeles, including transfers.