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How to get fromOsprey to Florida Keysby car, ferry, bus, shuttle, plane or bus (Flixbus, Greyhound)

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There are 6 ways to get from Osprey to Florida Keys by car, ferry, bus, shuttle, plane, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, ferry

    best
    1. Drive from Osprey to Fort Myers Beach, FLcar car
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    7h 28m
    $148–158
  2. Drive 322.5 mi

    cheapest
    1. Drive from Osprey to Florida Keyscar car 322.5 mi
    6h 28m
    $59–85
  3. Bus, shuttle

    1. Take the bus from Bradenton/Sarasota - Mobil Gas Station to Miami Airportbus bus Tallahassee-Miami
    2. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus To the Keys
    12h 37m
    $158–326
  4. Fly to Key West International Airport

    1. Fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW)plane plane SRQ - EYW
    10h 2m
    $458–772
  5. Bus

    1. Take the bus from Sarasota Cattlemen Transfer Center to Miami Airport Stationbus bus FlixBus 2421
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    13h 11m
    $62–100
  6. Fly to Miami International Airport, shuttle

    1. Fly from Sarasota–Bradenton International Airport (SRQ) to Miami International Airport (MIA)plane plane SRQ - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    8h 45m
    $344–738

Osprey to Florida Keys by bus, shuttle, and foot

Calendar7Weekly Services
Duration12h 37mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

What companies run services between Osprey, FL, USA and Florida Keys, FL, USA?

American Airlines and Delta fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from N Tamiami Trl @ Ogburn St to Florida Keys via Mall Dr @ Gateway Ave, Cattlemen Transit Station, Sarasota Cattlemen Transfer Center, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 13h 11m.

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Bus operators
Ferry operators

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