There are 7 ways to get from Orlando to Murrells Inlet by plane, train, car, bus (Flixbus, Greyhound), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Myrtle Beach
best- Fly from Orlando (MCO) to Myrtle Beach (MYR)MCO - MYR
2h 57m$122–302Train, drive (Amtrak)
cheapest- Take the train from Orlando to Kingstree StationSilver Meteor
- Drive from Kingstree Station to Murrells Inlet
10h 21m$59–172Bus
- Take the bus from Orlando Bus Station to Florence Bus StationFlixBus 2433
- Take the bus from Florence to Myrtle Beach, SCAtlanta
12h 21m$130–294Drive 457.8 mi
- Drive from Orlando to Murrells Inlet457.8 mi
8h 11m$84–121Bus to Tampa, fly to Myrtle Beach
- Take the bus from Orlando Bus Station to Tampa Bus Station
- Fly from Tampa (TPA) to Myrtle Beach (MYR)TPA - MYR
5h 27m$166–398Fly Orlando to Wilmington International Airport, bus
- Fly from Orlando (MCO) to Wilmington International Airport (ILM)MCO - ILM
- Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Station
5h 50m$136–388Train, bus
- Take the train from Orlando to Charleston Amtrak StationSilver Meteor
- Take the bus from Charleston Bus Station to Myrtle Beach Bus StationGreyhound US0641
11h 35m$119–262
Orlando (MCO) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Orlando to Murrells Inlet is to drive which costs $80 - $130 and takes 8h 11m.
The fastest way to get from Orlando to Murrells Inlet is to fly which takes 2h 57m and costs $120 - $310.
The distance between Orlando and Murrells Inlet is 421 miles. The road distance is 460.5 miles.
The best way to get from Orlando to Murrells Inlet without a car is to bus which takes 12h 21m and costs $130 - $300.
It takes approximately 2h 57m to get from Orlando to Murrells Inlet, including transfers.
The best way to get from Orlando to Murrells Inlet is to fly which takes 2h 57m and costs $120 - $310. Alternatively, you can bus, which costs $130 - $300 and takes 12h 21m.
Yes, the driving distance between Orlando to Murrells Inlet is 460 miles. It takes approximately 8h 11m to drive from Orlando to Murrells Inlet.
There are 2951+ hotels available in Murrells Inlet.
What companies run services between Orlando, FL, USA and Murrells Inlet, SC, USA?
Spirit Airlines and Breeze Airways fly from Orlando (MCO) to Myrtle Beach (MYR) 4 times a week. Alternatively, you can take a bus from Orlando Bus Station to Murrells Inlet via Florence Bus Station, Florence, and Myrtle Beach, SC in around 12h 21m.
- Website
- aa.com
Flights from Tampa to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $60–320
Flights from Orlando to Wilmington International Airport via Charlotte
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $55–310
- Website
- flybreeze.com
Flights from Orlando to Myrtle Beach
- Ave. Duration
- 1h 35m
- When
- Thursday and Sunday
- Estimated price
- $110–550
Flights from Tampa to Myrtle Beach
- Ave. Duration
- 1h 34m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $140–260
Flights from Orlando to Wilmington International Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $100–210
- Website
- delta.com
Flights from Tampa to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $60–330
- Website
- spirit.com
Flights from Orlando to Myrtle Beach
- Ave. Duration
- 1h 22m
- When
- Thursday and Sunday
- Estimated price
- $70–240
- Website
- aveloair.com
Flights from Orlando to Wilmington International Airport
- Ave. Duration
- 1h 34m
- When
- Thursday and Sunday
- Estimated price
- $35–310
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Orlando to Kingstree Station
- Ave. Duration
- 8h 49m
- Frequency
- Once daily
- Estimated price
- $45–160
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $45–120
- Coach Seat short notice purchase
- $55–160
- Business - advance purchase
- $80–340
- Business Class
- $130–370
Train from Orlando to Charleston Amtrak Station
- Ave. Duration
- 7h 49m
- Frequency
- Once daily
- Estimated price
- $60–200
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Orlando Bus Station to Florence Bus Station
- Ave. Duration
- 9h 35m
- Frequency
- Once daily
- Estimated price
- $70–150
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $13–25
- Schedules at
- flixbus.com
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Florence to Myrtle Beach, SC
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Florence to Myrtle Beach, SC
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $15–19
- Website
- https://www.greyhound.com/
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- $15–25
- Website
- https://www.greyhound.com/
Bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $15–23
- Website
- https://www.greyhound.com/
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $11–15
- Website
- https://www.greyhound.com/
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