There are 4 ways to get from Orlando to Lake City by bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  3 h 45 min

  1. Take the bus from Orlando, Fl to Lake City, Fl 1110

$21 - $50

3 alternative options

Bus via Jacksonville, Fl  •  4 h 7 min

  1. Take the bus from Orlando, Fl to Jacksonville, Fl 1002 / ...
  2. Take the bus from Jacksonville, Fl to Lake City, Fl 3743 / ...

$32 - $73

Train, bus  •  4 h 57 min

  1. Take the train from Orlando Amtrak to Jacksonville Amtrak Silver Star / ...
  2. Take the bus from Jacksonville, Fl to Lake City, Fl 3743 / ...

$66 - $131

Drive  •  2 h 31 min

  1. Drive from Orlando to Lake City 154.2 miles

$15 - $22

Questions & Answers

The cheapest way to get from Orlando to Lake City is to drive which costs $15 - $22 and takes 2 h 31 min.

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The quickest way to get from Orlando to Lake City is to drive which costs $15 - $22 and takes 2 h 31 min.

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Yes, there is a direct bus departing from Orlando, Fl and arriving at Lake City, Fl. Services depart every two hours, and operate every day. The journey takes approximately 3 h 45 min.

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The distance between Orlando and Lake City is 138 miles. The road distance is 154.2 miles.

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The best way to get from Orlando to Lake City without a car is to bus which takes 3 h 45 min and costs $21 - $50.

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The bus from Orlando, Fl to Lake City, Fl takes 3 h 45 min including transfers and departs every two hours.

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Orlando to Lake City bus services, operated by Greyhound USA, depart from Orlando, Fl station.

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Orlando to Lake City bus services, operated by Greyhound USA, arrive at Lake City, Fl station.

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Yes, the driving distance between Orlando to Lake City is 154 miles. It takes approximately 2 h 31 min to drive from Orlando to Lake City.

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Book your Orlando to Lake City bus tickets online with Greyhound.

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Map of how to get from Orlando to Lake City.
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  • Distance: 137.8 miles
  • Duration: 3 h 45 min

What companies run services between Orlando, FL, USA and Lake City, FL, USA?

Greyhound USA operates a bus from Orlando to Lake City every 2 hours. Tickets cost $21 - $50 and the journey takes 3 h 45 min.

Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Orlando Amtrak to Jacksonville Amtrak
Ave. Duration
3 h 11 min
Frequency
Twice daily
Estimated price
$35 - $85
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$60 - $90
Business Coach Seat
$55 - $85
Room
$180 - $250
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Orlando, Fl to Lake City, Fl
Ave. Duration
3 h 45 min
Frequency
Every 2 hours
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50
Bus from Orlando, Fl to Jacksonville, Fl
Ave. Duration
2 h 30 min
Frequency
Every 30 minutes
Estimated price
$19 - $50
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $50
Bus from Jacksonville, Fl to Lake City, Fl
Ave. Duration
1 h 5 min
Frequency
Hourly
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $18
Flexible
$21 - $28

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