There are 4 ways to get from Orlando to Lake City by bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  3 h 45 min

  1. Take the bus from Orlando, Fl to Lake City, Fl 1110

$21 - $50

3 alternative options

Bus via Jacksonville, Fl  •  4 h 7 min

  1. Take the bus from Orlando, Fl to Jacksonville, Fl 1002 / ...
  2. Take the bus from Jacksonville, Fl to Lake City, Fl 3743 / ...

$32 - $73

Train, bus  •  4 h 57 min

  1. Take the train from Orlando Amtrak to Jacksonville Amtrak Silver Star / ...
  2. Take the bus from Jacksonville, Fl to Lake City, Fl 3743 / ...

$66 - $131

Drive  •  2 h 31 min

  1. Drive from Orlando to Lake City 154.2 miles

$15 - $22

What companies run services between Orlando, FL, USA and Lake City, FL, USA?

Greyhound USA operates a bus from Orlando to Lake City every 2 hours. Tickets cost $21 - $50 and the journey takes 3 h 45 min.

Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Orlando Amtrak to Jacksonville Amtrak
Ave. Duration
3 h 11 min
Frequency
Twice daily
Estimated price
$35 - $85
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$60 - $90
Business Coach Seat
$55 - $85
Room
$180 - $250
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Orlando, Fl to Lake City, Fl
Ave. Duration
3 h 45 min
Frequency
Every 2 hours
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50
Bus from Orlando, Fl to Jacksonville, Fl
Ave. Duration
2 h 30 min
Frequency
Every 30 minutes
Estimated price
$19 - $50
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $50
Bus from Jacksonville, Fl to Lake City, Fl
Ave. Duration
1 h 5 min
Frequency
Hourly
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $18
Flexible
$21 - $28

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Questions & Answers

How far is it from Orlando to Lake City?

The distance between Orlando and Lake City is 221 km. The road distance is 247 km.

What is the cheapest way to get from Orlando to Lake City?

The cheapest way to get from Orlando to Lake City is to drive which costs $15 - $22 and takes 2 h 31 min.

What is the fastest way to get from Orlando to Lake City?

The quickest way to get from Orlando to Lake City is to drive which takes 2 h 31 min and costs $15 - $22.

Is there a direct bus between Orlando and Lake City?

Yes, there is a direct bus departing from Orlando, Fl and arriving at Lake City, Fl. Services depart every two hours, and operate every day. The journey takes approximately 3 h 45 min.

How long does it take to get from Orlando to Lake City?

The bus from Orlando, Fl to Lake City, Fl takes 3 h 45 min including transfers and departs every two hours.