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How to get fromOrlando to Irmoby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 5 ways to get from Orlando to Irmo by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to Columbia

    best
    1. Fly from Orlando (MCO) to Columbia (CAE)plane plane MCO - CAE
    5h 20m
    $197–912

  2. Drive 435.9 mi

    cheapest
    1. Drive from Orlando to Irmocar car 435.9 mi
    7h 9m
    $80–115

  3. Bus

    1. Take the bus from Orlando Bus Station to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Camdenbus bus
    3. Take the bus from Camden to Columbia, SCbus bus Nyc
    14h 20m
    $105–181

  4. Train, bus

    1. Take the train from Orlando to Fayetteville Amtrak Stationtrain train
    2. Take the bus from Fayetteville Bus Station to Camdenbus bus
    3. Take the bus from Camden to Columbia, SCbus bus Nyc
    16h 52m
    $255–486

  5. Fly Orlando Sanford to Greenville–Spartanburg International Airport, drive

    1. Fly from Orlando Sanford (SFB) to Greenville–Spartanburg International Airport (GSP)plane plane SFB - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Irmocar car
    3h 44m
    $157–587

Orlando (MCO) to Columbia (CAE) flights

Calendar132Weekly Planes
Duration4h 58mAverage Duration
Ticket$151Cheapest Price
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Questions & Answers

Map of how to get from Orlando to Irmo.ExpandLaunch map view
  • Distance: 412.2 mi
  • Duration: 5h 20m

What companies run services between Orlando, FL, USA and Irmo, SC, USA?

Delta, American Airlines, and United Airlines fly from Orlando (MCO) to Columbia (CAE) hourly. Alternatively, you can take a bus from Orlando Bus Station to Midlands Tech College Harbison via Jacksonville, Camden, Columbia, SC, Broad Marley North, and Harbison Walmart in around 14h 20m.

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