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There are 8 ways to get from Orlando to Great Smoky Mountains by plane, car, train or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Orlando to Knoxville, drive  •  5h 25m

  1. Fly from Orlando (MCO) to Knoxville (TYS) MCO - TYS
  2. Drive from Knoxville to Great Smoky Mountains

$98 - $462

Cheapest option

Bus, drive via Jacksonville, Fl  •  22h 38m

  1. Take the bus from Orlando, Fl to Jacksonville, Fl
  2. Take the bus from Jacksonville, Fl to Winston Salem, Nc
  3. Take the bus from Winston Salem, Nc to Asheville, Nc
  4. Drive from Asheville, Nc to Great Smoky Mountains

$97 - $239

6 alternative options

Fly Orlando to Asheville, drive  •  5h 32m

  1. Fly from Orlando (MCO) to Asheville (AVL) MCO - AVL
  2. Drive from Asheville to Great Smoky Mountains

$240 - $444

Train to Orlando Sanford, fly to Knoxville, drive  •  5h 29m

  1. Take the train from Church Street to Sanford
  2. Fly from Orlando Sanford (SFB) to Knoxville (TYS) SFB - TYS
  3. Drive from Knoxville to Great Smoky Mountains

$104 - $229

Fly Orlando Sanford to Asheville, drive  •  5h 35m

  1. Fly from Orlando Sanford (SFB) to Asheville (AVL) SFB - AVL
  2. Drive from Asheville to Great Smoky Mountains

$141 - $421

Train, bus, drive  •  22h 8m

  1. Take the train from Orlando Amtrak Station to Cary Amtrak Station
  2. Take the train from Cary Amtrak Station to Greensboro Amtrak Station
  3. Take the bus from Greensboro, Nc to Asheville, Nc
  4. Drive from Asheville, Nc to Great Smoky Mountains

$146 - $373

Bus Lacubanabus, drive  •  23h 19m

  1. Take the bus from Orlando, FL to Fayetteville, NC
  2. Take the bus from Fayetteville, NC to Durham, NC
  3. Take the bus from Durham, Nc to Asheville, Nc
  4. Drive from Asheville, Nc to Great Smoky Mountains

Drive  •  10h 57m

  1. Drive from Orlando to Great Smoky Mountains 624.7 miles

$60 - $90

Questions & Answers

The cheapest way to get from Orlando to Great Smoky Mountains is to drive which costs $60 - $90 and takes 10h 57m.

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The quickest way to get from Orlando to Great Smoky Mountains is to fly and drive which costs $95 - $470 and takes 5h 25m.

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The distance between Orlando and Great Smoky Mountains is 505 miles. The road distance is 624.7 miles.

Get driving directions

It takes approximately 5h 25m to get from Orlando to Great Smoky Mountains, including transfers.

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The quickest flight from Orlando Airport to Knoxville Airport is the direct flight which takes 1h 46m.

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Yes, the driving distance between Orlando to Great Smoky Mountains is 625 miles. It takes approximately 10h 57m to drive from Orlando to Great Smoky Mountains.

Get driving directions

Frontier Airlines, American Airlines and Delta offer flights from Orlando Airport to Knoxville Airport.

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There are 1476+ hotels available in Great Smoky Mountains. Prices start at $127 USD per night.

More details

The best way to get from Orlando to Orlando Airport is to line 11 bus which takes 41m and costs $3.

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Map of how to get from Orlando to Great Smoky Mountains.
Launch map view
  • Distance: 505.4 miles
  • Duration: 5h 25m

What companies run services between Orlando, FL, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Orlando to Great Smoky Mountains. However, you can take the line 11 bus to Oia Transfer Center, take the walk to Orlando airport, fly to Knoxville, then take the drive to Great Smoky Mountains. Alternatively, you can take the line 11 bus to Oia Transfer Center, take the walk to Orlando airport, fly to Asheville, then take the drive to Great Smoky Mountains.

Airlines
Delta
Website
delta.com
Flights from Orlando to Knoxville via Atlanta
Ave. Duration
3h 51m
When
Every day
Estimated price
$160 - $850
Flights from Orlando to Asheville via Atlanta
Ave. Duration
3h 54m
When
Every day
Estimated price
$470 - $850
American Airlines
Website
aa.com
Flights from Orlando to Knoxville via Charlotte
Ave. Duration
4h 5m
When
Every day
Estimated price
$180 - $850
Flights from Orlando to Asheville via Charlotte
Ave. Duration
3h 52m
When
Every day
Estimated price
$460 - $850
Allegiant Air
Website
allegiantair.com
Flights from Orlando Sanford to Knoxville
Ave. Duration
1h 33m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$110 - $380
Flights from Orlando Sanford to Asheville
Ave. Duration
1h 30m
When
Every day
Estimated price
$110 - $380
Frontier Airlines
Website
flyfrontier.com
Flights from Orlando to Knoxville
Ave. Duration
1h 46m
When
Monday and Friday
Estimated price
$90 - $450
Spirit Airlines
Website
spirit.com
Flights from Orlando to Asheville
Ave. Duration
1h 42m
When
Monday, Friday and Saturday
Estimated price
$85 - $400
Train operators
SunRail
Website
sunrail.com
Train from Church Street to Sanford
Ave. Duration
45m
Frequency
Hourly
Estimated price
$2 - $4
Schedules at
sunrail.com
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Orlando Amtrak Station to Cary Amtrak Station
Ave. Duration
12h 36m
Frequency
Once daily
Estimated price
$90 - $260
Website
amtrak.com
Coach Seat
$90 - $140
Flexi Coach Seat
$160 - $230
Business Coach Seat
$180 - $260
Room
$370 - $550
Train from Cary Amtrak Station to Greensboro Amtrak Station
Ave. Duration
1h 19m
Frequency
4 times a day
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Greensboro, Nc to Asheville, Nc
Ave. Duration
4h 10m
Frequency
Once daily
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Orlando, Fl to Jacksonville, Fl
Ave. Duration
3h 10m
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Bus from Jacksonville, Fl to Winston Salem, Nc
Ave. Duration
12h 30m
Frequency
3 times a day
Estimated price
$50 - $130
Website
greyhound.com
Economy
$50 - $80
Flexible
$95 - $130
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2h 55m
Frequency
Once daily
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Bus from Durham, Nc to Asheville, Nc
Ave. Duration
5h 20m
Frequency
Once daily
Estimated price
$27 - $65
Website
greyhound.com
Economy
$27 - $45
Flexible
$50 - $65
bus
Bus from Orlando, FL to Fayetteville, NC
Ave. Duration
8h 15m
Frequency
5 times a week
Schedules at
lacubanabus.com

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