There are 7 ways to get from Orlando to Great Smoky Mountains by plane, car, bus or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Orlando Sanford to Knoxville, drive  •  5 h 18 min

  1. Fly from Orlando Sanford (SFB) to Knoxville (TYS) SFB - TYS
  2. Drive from Knoxville to Great Smoky Mountains

$102 - $225

Cheapest option

Megabus, drive  •  17 h 53 min

  1. Take the Megabus from Orlando to Midtown Atlanta
  2. Take the Megabus from Atlanta GA to Knoxville
  3. Drive from Mountain Grove SB before Majestic Grove to Great Smoky Mountains

$61 - $107

5 alternative options

Fly Orlando to Knoxville, drive  •  7 h 4 min

  1. Fly from Orlando (MCO) to Knoxville (TYS) MCO - TYS
  2. Drive from Knoxville to Great Smoky Mountains

$171 - $866

Fly Orlando Sanford to Asheville, drive  •  5 h 25 min

  1. Fly from Orlando Sanford (SFB) to Asheville (AVL) SFB - AVL
  2. Drive from Asheville to Great Smoky Mountains

$139 - $417

Bus, Megabus, drive  •  15 h 2 min

  1. Take the bus from Orlando, Fl to Atlanta, Ga
  2. Take the Megabus from Atlanta GA to Knoxville
  3. Drive from Knoxville to Great Smoky Mountains

$77 - $160

Train, bus, drive  •  21 h 59 min

  1. Take the train from Orlando Amtrak to Cary Amtrak
  2. Take the train from Cary Amtrak to Greensboro Galyon Transportation Center Amtrak
  3. Take the bus from Greensboro, Nc to Winston Salem, Nc
  4. Take the bus from Winston Salem, Nc to Asheville, Nc
  5. Drive from Asheville, Nc to Great Smoky Mountains

$153 - $388

Drive  •  10 h 57 min

  1. Drive from Orlando to Great Smoky Mountains 624.7 miles

$60 - $90

Questions & Answers

The cheapest way to get from Orlando to Great Smoky Mountains is to drive which costs $60 - $90 and takes 10 h 57 min.

More details

The quickest way to get from Orlando to Great Smoky Mountains is to fly and drive which takes 5 h 18 min and costs $100 - $230.

More details

The distance between Orlando and Great Smoky Mountains is 809 km. The road distance is 1000 km.

Get driving directions

It takes approximately 5 h 18 min to get from Orlando to Great Smoky Mountains, including transfers.

More details

What companies run services between Orlando, FL, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Orlando to Great Smoky Mountains. However, you can take the train to Lake Mary, take the taxi to Orlando Sanford airport, fly to Knoxville, then take the drive to Great Smoky Mountains. Alternatively, you can take the train to Sand Lake Road, take the walk to Sand Lake Rd Sunrail Station, take the line 111 bus to Oia Transfer Center, take the walk to Orlando airport, fly to Knoxville, then take the drive to Great Smoky Mountains.

Airlines
Delta
Website
delta.com
Flights from Orlando to Knoxville via Atlanta
Ave. Duration
3 h 53 min
When
Every day
Estimated price
$160 - $850
Flights from Orlando to Knoxville via Detroit
Ave. Duration
5 h 41 min
When
Every day
Estimated price
$220 - $1,000
American Airlines
Website
aa.com
Flights from Orlando to Knoxville via Charlotte
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$180 - $850
Flights from Orlando to Knoxville via Philadelphia
Ave. Duration
5 h 46 min
When
Every day
Estimated price
$230 - $1,000
Flights from Orlando to Knoxville via Dallas/Ft.Worth
Ave. Duration
5 h 56 min
When
Every day
Estimated price
$260 - $1,000
Allegiant Air
Website
allegiantair.com
Flights from Orlando Sanford to Knoxville
Ave. Duration
1 h 31 min
When
Every day
Estimated price
$110 - $380
Flights from Orlando Sanford to Asheville
Ave. Duration
1 h 28 min
When
Monday, Tuesday, Wednesday, Friday and Saturday
Estimated price
$110 - $380
United Airlines
Website
united.com
Flights from Orlando to Knoxville via Washington Dulles
Ave. Duration
5 h 15 min
When
Every day
Estimated price
$220 - $1,000
Flights from Orlando to Knoxville via Newark
Ave. Duration
5 h 55 min
When
Every day
Estimated price
$250 - $1,100
Flights from Orlando to Knoxville via Houston
Ave. Duration
6 h 5 min
When
Every day
Estimated price
$250 - $1,100
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Orlando Amtrak to Cary Amtrak
Ave. Duration
12 h 36 min
Frequency
Once daily
Estimated price
$90 - $260
Website
amtrak.com
Coach Seat
$90 - $140
Flexi Coach Seat
$160 - $230
Business Coach Seat
$180 - $260
Room
$370 - $550
Train from Cary Amtrak to Greensboro Galyon Transportation Center Amtrak
Ave. Duration
1 h 19 min
Frequency
3 times a day
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Bus operators
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Orlando, Fl to Atlanta, Ga
Ave. Duration
8 h 5 min
Frequency
Hourly
Estimated price
$45 - $120
Website
greyhound.com
Economy
$45 - $75
Flexible
$85 - $120
Bus from Greensboro, Nc to Winston Salem, Nc
Ave. Duration
45 min
Frequency
Hourly
Estimated price
$9 - $20
Website
greyhound.com
Economy
$9 - $14
Flexible
$16 - $20
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Every 2 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Atlanta GA to Knoxville
Ave. Duration
4 h 5 min
Frequency
Twice daily
Estimated price
$22 - $35
Schedules at
us.megabus.com
Bus from Orlando to Midtown Atlanta
Ave. Duration
9 h 5 min
Frequency
3 times a day
Estimated price
$30 - $60
Schedules at
us.megabus.com

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