There are 7 ways to get from Orlando to Clemson by plane, taxi, bus (Flixbus), train (Amtrak), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Greenville–Spartanburg International Airport, taxi
best- Fly from Orlando (MCO) to Greenville–Spartanburg International Airport (GSP)plane MCO - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Clemsontaxi
4h 4m$232–682Drive 495.4 mi
cheapest- Drive from Orlando to Clemsoncar 495.4 mi
9h 26m$91–131Bus
- Take the bus from Orlando Bus Station to Charlotte Bus Stationbus FlixBus 2433
- Take the bus from Charlotte, NC to Anderson, SCbus Nyc
13h 12m$163–309Train (Amtrak)
- Take the train from Orlando to Carytrain
- Take the train from Cary to Charlotte Amtrak Stationtrain
- Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain
21h 35m$123–286Fly Orlando Sanford to Asheville Regional Airport, drive
- Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane SFB - AVL
- Drive from Asheville-Airport-AVL to Clemsoncar
3h 42m$127–429Fly Orlando Sanford to Greenville–Spartanburg International Airport, taxi
- Fly from Orlando Sanford (SFB) to Greenville–Spartanburg International Airport (GSP)plane SFB - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Clemsontaxi
2h 57m$229–660Bus, train
- Take the bus from Orlando Bus Station to Charlotte Bus Stationbus FlixBus 2433
- Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain Crescent
14h 45m$115–251
Orlando to Clemson by train (Amtrak)
Questions & Answers
The cheapest way to get from Orlando to Clemson is to drive which costs $90 - $140 and takes 9h 26m.
The fastest way to get from Orlando to Clemson is to fly and taxi which takes 2h 57m and costs $220 - $700.
No, there is no direct train from Orlando to Clemson station. However, there are services departing from Orlando and arriving at Clemson Amtrak Station via Cary and Charlotte Amtrak Station. The journey, including transfers, takes approximately 21h 35m.
The distance between Orlando and Clemson is 511 miles. The road distance is 498.3 miles.
The best way to get from Orlando to Clemson without a car is to bus which takes 13h 12m and costs $160 - $310.
It takes approximately 4h 4m to get from Orlando to Clemson, including transfers.
Orlando to Clemson train services, operated by Amtrak, depart from Orlando station.
The best way to get from Orlando to Clemson is to bus which takes 13h 12m and costs $160 - $310. Alternatively, you can train, which costs $120 - $290 and takes 21h 35m.
Orlando to Clemson train services, operated by Amtrak, arrive at Cary station.
Yes, the driving distance between Orlando to Clemson is 498 miles. It takes approximately 9h 26m to drive from Orlando to Clemson.
What companies run services between Orlando, FL, USA and Clemson, SC, USA?
You can take a bus from Orlando Bus Station to Clemson via Charlotte Bus Station, Charlotte, NC, and Anderson, SC in around 13h 12m. Alternatively, you can take a train from Orlando to Clemson Amtrak Station via Cary and Charlotte Amtrak Station in around 21h 35m.
- Website
- delta.com
Flights from Orlando to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $65–400
- Website
- allegiantair.com
Flights from Orlando Sanford to Asheville Regional Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $55–340
Flights from Orlando Sanford to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 26m
- When
- Thursday and Sunday
- Estimated price
- $70–460
- Website
- aa.com
Flights from Orlando to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $65–400
- Website
- flybreeze.com
Flights from Orlando to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 53m
- When
- Monday and Friday
- Estimated price
- $130–550
- Website
- southwest.com
Flights from Orlando to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $85–470
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Orlando to Cary
- Ave. Duration
- 13h 25m
- Frequency
- Once daily
- Estimated price
- $55–200
- Website
- https://www.amtrak.com/home.html
Train from Cary to Charlotte Amtrak Station
- Ave. Duration
- 2h 58m
- Frequency
- 5 times a day
- Estimated price
- $28–33
- Website
- https://www.amtrak.com/home.html
Train from Charlotte Amtrak Station to Clemson Amtrak Station
- Ave. Duration
- 3h 12m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Orlando Bus Station to Charlotte Bus Station
- Ave. Duration
- 10h
- Frequency
- Twice daily
- Estimated price
- $75–190
- Schedules at
- flixbus.com
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Charlotte, NC to Anderson, SC
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Estimated price
- $40–60
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Ave. Duration
- 56 min
- Estimated price
- $100–130
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Corporate Taxi
- Phone
- +1 864-990-5556
- Website
- ataxi.co
Atlantis Taxi
- Phone
- +1 850-628-5670
- Website
- facebook.com
Checker Cab
- Phone
- +1 864-583-2721
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Corporate Taxi
- Phone
- +1 864-990-5556
- Website
- ataxi.co
Atlantis Taxi
- Phone
- +1 850-628-5670
- Website
- facebook.com
Checker Cab
- Phone
- +1 864-583-2721
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Book your Orlando to Clemson train tickets online with Omio.
There are 105+ hotels available in Clemson.




