• Our partners include:

  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
  • Megabus
  • SuperShuttle
  • Booking.com
  • Skyscanner
  • Airbnb
  • Expedia

There are 7 ways to get from Orlando Health/Amtrak to Des Moines by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Orlando  •  6 h 12 min

  1. Fly from Orlando (MCO) to Des Moines (DSM) MCO - DSM

$166 - $858

Cheapest option

Megabus, bus  •  37 h 26 min

  1. Take the Megabus from Orlando to Midtown Atlanta
  2. Take the bus from Marta Civic Center Station - Nb to Chicago
  3. Take the bus from Chicago, IL to Des Moines, IA

$137 - $227

5 alternative options

Fly from Orlando Sanford  •  6 h 20 min

  1. Fly from Orlando Sanford (SFB) to Des Moines (DSM) SFB - DSM

$154 - $581

Bus  •  34 h 14 min

  1. Take the bus from Orlando, Fl to Tallahassee, Fl
  2. Take the bus from Tallahassee, Fl to St Louis, Mo
  3. Take the bus from St Louis, Mo to Kansas City, Mo
  4. Take the bus from Kansas City, MO to Des Moines, IA 802 / ...

$191 - $430

Train, bus  •  44 h 45 min

  1. Take the train from Orlando Amtrak Station to Washington Union Station
  2. Take the train from Washington Union Station to Chicago Union Station
  3. Take the train from Chicago Union Station to Ottumwa Amtrak Station
  4. Take the bus from Ottumwa, IA to Des Moines, IA

$295 - $822

Train, bus via Alexandria Amtrak Station  •  2 days 2 h

  1. Take the train from Orlando Amtrak Station to Alexandria Amtrak Station
  2. Take the train from Alexandria Amtrak Station to Chicago Union Station
  3. Take the train from Chicago Union Station to Ottumwa Amtrak Station
  4. Take the bus from Ottumwa, IA to Des Moines, IA

$315 - $859

Drive  •  22 h 48 min

  1. Drive from Orlando Health/Amtrak to Des Moines 1346.9 miles

$130 - $200

Questions & Answers

The cheapest way to get from Orlando Health/Amtrak to Des Moines is to drive which costs $130 - $200 and takes 22 h 48 min.

More details

The quickest way to get from Orlando Health/Amtrak to Des Moines is to fly which costs $160 - $900 and takes 6 h 12 min.

More details

No, there is no direct bus from Orlando Health/Amtrak station to Des Moines. However, there are services departing from Orland Health Sunrail Station and arriving at Des Moines, IA via Lynx Central Station - Sunrail, Orlando, Marta Civic Center Station - Nb and Chicago, IL. The journey, including transfers, takes approximately 37 h 26 min.

More details

The distance between Orlando Health/Amtrak and Des Moines is 1142 miles. The road distance is 1346.9 miles.

Get driving directions

The best way to get from Orlando Health/Amtrak to Des Moines without a car is to bus which takes 34 h 14 min and costs $190 - $430.

More details

It takes approximately 6 h 12 min to get from Orlando Health/Amtrak to Des Moines, including transfers.

More details

Orlando Health/Amtrak to Des Moines bus services, operated by Megabus, depart from Orlando station.

More details

The best way to get from Orlando Health/Amtrak to Des Moines is to fly which takes 6 h 12 min and costs $160 - $900. Alternatively, you can bus, which costs $190 - $430 and takes 34 h 14 min.

Mode details

The quickest flight from Orlando Airport to Des Moines Airport is the direct flight which takes 3 h 9 min.

Search flights

Orlando Health/Amtrak to Des Moines bus services, operated by Burlington Trailways, arrive at Des Moines, IA station.

More details

Map of how to get from Orlando Health/Amtrak to Des Moines.
Launch map view
  • Distance: 1141.7 miles
  • Duration: 6 h 12 min

What companies run services between Orlando Health/Amtrak, FL, USA and Des Moines, IA, USA?

Frontier Airlines, Southwest Airlines and three other airlines fly from Orlando Health/Amtrak to Des Moines hourly. Alternatively, you can take a bus from Orlando Health/Amtrak to Des Moines via Orlando, Fl, Tallahassee, Fl, St Louis, Mo, Kansas City, Mo, and Kansas City, MO in around 34 h 14 min.

Airlines
United Airlines
Website
united.com
Flights from Orlando to Des Moines via Chicago O'Hare
Ave. Duration
5 h 37 min
When
Every day
Estimated price
$160 - $1,600
Flights from Orlando to Des Moines via Houston
Ave. Duration
5 h 36 min
When
Every day
Estimated price
$160 - $1,600
Delta
Website
delta.com
Flights from Orlando to Des Moines via Atlanta
Ave. Duration
5 h 22 min
When
Every day
Estimated price
$160 - $1,800
American Airlines
Website
aa.com
Flights from Orlando to Des Moines via Charlotte
Ave. Duration
5 h 44 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $2,000
Flights from Orlando to Des Moines via Dallas/Ft.Worth
Ave. Duration
5 h 38 min
When
Monday, Thursday, Friday and Sunday
Estimated price
$170 - $2,000
Southwest Airlines
Website
southwest.com
Flights from Orlando to Des Moines via St. Louis
Ave. Duration
4 h 35 min
When
Sunday
Estimated price
$210 - $1,800
Frontier Airlines
Website
flyfrontier.com
Flights from Orlando to Des Moines
Ave. Duration
3 h 9 min
When
Wednesday and Saturday
Estimated price
$110 - $500
Allegiant Air
Website
allegiantair.com
Flights from Orlando Sanford to Des Moines
Ave. Duration
3 h 4 min
When
Thursday and Sunday
Estimated price
$130 - $550
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Orlando Amtrak Station to Washington Union Station
Ave. Duration
17 h 32 min
Frequency
Twice daily
Estimated price
$120 - $350
Website
amtrak.com
Coach Seat
$120 - $180
Flexi Coach Seat
$210 - $310
Business Coach Seat
$250 - $350
Room
$490 - $700
Train from Washington Union Station to Chicago Union Station
Ave. Duration
17 h 40 min
Frequency
Once daily
Estimated price
$100 - $310
Website
amtrak.com
Coach Seat
$100 - $160
Flexi Coach Seat
$190 - $280
Business Coach Seat
$220 - $310
Room
$440 - $600
Train from Chicago Union Station to Ottumwa Amtrak Station
Ave. Duration
4 h 53 min
Frequency
Twice daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Train from Orlando Amtrak Station to Alexandria Amtrak Station
Ave. Duration
17 h 1 min
Frequency
Twice daily
Estimated price
$120 - $350
Website
amtrak.com
Coach Seat
$120 - $180
Flexi Coach Seat
$210 - $310
Business Coach Seat
$250 - $350
Room
$480 - $700
Train from Alexandria Amtrak Station to Chicago Union Station
Ave. Duration
23 h 41 min
Frequency
4 times a week
Estimated price
$120 - $350
Website
amtrak.com
Coach Seat
$120 - $180
Flexi Coach Seat
$210 - $310
Business Coach Seat
$250 - $350
Room
$490 - $700
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Orlando, Fl to Tallahassee, Fl
Ave. Duration
5 h 15 min
Frequency
Every 2 hours
Estimated price
$29 - $75
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $75
Bus from Tallahassee, Fl to St Louis, Mo
Ave. Duration
18 h 35 min
Frequency
Once daily
Estimated price
$85 - $220
Website
greyhound.com
Economy
$85 - $140
Flexible
$160 - $220
Bus from St Louis, Mo to Kansas City, Mo
Ave. Duration
4 h 25 min
Frequency
4 times a day
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Kansas City, MO to Des Moines, IA
Ave. Duration
2 h 55 min
Frequency
3 times a day
Estimated price
$40 - $55
Book at
jeffersonlines.com
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Orlando to Midtown Atlanta
Ave. Duration
7 h 40 min
Frequency
3 times a day
Estimated price
$35 - $55
Book at
megabus.com
Bus from Marta Civic Center Station - Nb to Chicago
Ave. Duration
14 h 30 min
Frequency
Twice daily
Estimated price
$60 - $85
Book at
megabus.com
Burlington Trailways
Website
burlingtontrailways.com
Bus from Chicago, IL to Des Moines, IA
Ave. Duration
11 h 25 min
Frequency
Once daily
Estimated price
$40 - $85
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Ottumwa, IA to Des Moines, IA
Ave. Duration
1 h 40 min
Frequency
Once daily
Estimated price
$23 - $35
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Des Moines is 1 h behind Orlando Health/Amtrak. It is currently 11:14 PM in Orlando Health/Amtrak and 10:14 PM in Des Moines.

Yes, the driving distance between Orlando Health/Amtrak to Des Moines is 1347 miles. It takes approximately 22 h 48 min to drive from Orlando Health/Amtrak to Des Moines.

Get driving directions

Frontier Airlines, Southwest Airlines, Delta and two other airlines offer flights from Orlando Airport to Des Moines Airport.

Search flights

There are 105+ hotels available in Des Moines. Prices start at $71 USD per night.

More details