There are 6 ways to get from Orlando Airport (MCO) to Greenville by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  2 h 2 min

  1. Fly from Orlando (MCO) to Greenville/Spartanburg (GSP) MCO - GSP

$107 - $424

Cheapest option

Bus Megabus  •  21 h 36 min

  1. Take the bus from Orlando to Atlanta, GA
  2. Take the bus from Atlanta, GA to Greenville

$63 - $138

4 alternative options

Bus Greyhound USA  •  15 h 1 min

  1. Take the bus from Orlando, Fl to Atlanta, Ga 1154 / ...
  2. Take the bus from Atlanta, Ga to Greenville, Sc 1078 / ...

$98 - $217

Train, bus  •  21 h 5 min

  1. Take the train from Winter Park Amtrak to Savannah Amtrak
  2. Take the bus from Savannah to Columbia
  3. Take the bus from Columbia to Greenville

$105 - $252

Train  •  21 h 20 min

  1. Take the train from Orlando Amtrak to Cary Amtrak
  2. Take the train from Cary Amtrak to Charlotte Amtrak
  3. Take the train from Charlotte Amtrak to Greenville Amtrak

$159 - $425

Drive  •  8 h 56 min

  1. Drive from Orlando Airport (MCO) to Greenville 547.3 miles

$50 - $80

Questions & Answers

The cheapest way to get from Orlando Airport (MCO) to Greenville is to drive which costs $50 - $80 and takes 8 h 56 min.

More details

The quickest way to get from Orlando Airport (MCO) to Greenville is to fly which costs $100 - $430 and takes 2 h 2 min.

More details

The distance between Orlando Airport (MCO) and Greenville is 451 miles. The road distance is 547.3 miles.

Get driving directions

It takes approximately 2 h 2 min to get from Orlando Airport (MCO) to Greenville, including transfers.

More details

What companies run services between Orlando Airport (MCO), USA and Greenville, SC, USA?

Frontier Airlines, American Airlines and two other airlines fly from Orlando Airport (MCO) to Greenville hourly. Alternatively, you can take a bus from Orlando Airport (MCO) to Greenville via Lynx Kissimmee Intermodal Station, Kissimmee, Fl, Orlando, Fl, Atlanta, Ga, and Greenville, Sc in around 15 h 1 min.

Airlines
American Airlines
Website
aa.com
Flights from Orlando to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 35 min
When
Every day
Estimated price
$150 - $750
Delta
Website
delta.com
Flights from Orlando to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 43 min
When
Every day
Estimated price
$140 - $750
Southwest Airlines
Website
southwest.com
Flights from Orlando to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 32 min
When
Saturday and Sunday
Estimated price
$160 - $700
Frontier Airlines
Website
flyfrontier.com
Flights from Orlando to Greenville/Spartanburg
Ave. Duration
1 h 45 min
When
Wednesday and Saturday
Estimated price
$75 - $380
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Winter Park Amtrak to Savannah Amtrak
Ave. Duration
5 h 27 min
Frequency
Twice daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $130
Business Coach Seat
$95 - $140
Room
$230 - $330
Train from Orlando Amtrak to Cary Amtrak
Ave. Duration
12 h 36 min
Frequency
Once daily
Estimated price
$90 - $260
Website
amtrak.com
Coach Seat
$90 - $140
Flexi Coach Seat
$160 - $230
Business Coach Seat
$180 - $260
Room
$370 - $550
Train from Cary Amtrak to Charlotte Amtrak
Ave. Duration
2 h 58 min
Frequency
4 times a day
Estimated price
$35 - $90
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$65 - $95
Business Coach Seat
$60 - $90
Room
$180 - $260
Train from Charlotte Amtrak to Greenville Amtrak
Ave. Duration
2 h 9 min
Frequency
Once daily
Estimated price
$30 - $70
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$50 - $80
Business Coach Seat
$45 - $70
Room
$160 - $230
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Orlando, Fl to Atlanta, Ga
Ave. Duration
8 h 5 min
Frequency
Hourly
Estimated price
$45 - $120
Website
greyhound.com
Economy
$45 - $75
Flexible
$85 - $120
Bus from Atlanta, Ga to Greenville, Sc
Ave. Duration
3 h 40 min
Frequency
Hourly
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Savannah to Columbia
Ave. Duration
8 h 30 min
Frequency
Once daily
Estimated price
$27 - $70
Schedules at
southeasternstages.com
Bus from Columbia to Greenville
Ave. Duration
1 h 50 min
Frequency
Once daily
Estimated price
$22 - $35
Schedules at
southeasternstages.com
Bus from Atlanta, GA to Greenville
Ave. Duration
9 h 20 min
Frequency
Once daily
Estimated price
$35 - $70
Schedules at
southeasternstages.com

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