There are 7 ways to get from Orlando Airport (MCO) to Greenville by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Greenville/Spartanburg  •  3 h 47 min

  1. Fly from Orlando (MCO) to Greenville/Spartanburg (GSP) MCO - GSP

$173 - $766

Cheapest option

Bus Megabus  •  21 h 36 min

  1. Take the bus from Orlando to Atlanta, GA
  2. Take the bus from Atlanta, GA to Greenville

$63 - $138

5 alternative options

Fly to Charlotte, train  •  5 h 44 min

  1. Fly from Orlando (MCO) to Charlotte (CLT) MCO - CLT
  2. Take the train from Charlotte Amtrak to Greenville Amtrak

$110 - $418

Bus Greyhound USA  •  15 h 1 min

  1. Take the bus from Orlando, Fl to Atlanta, Ga 1154 / ...
  2. Take the bus from Atlanta, Ga to Greenville, Sc 1078 / ...

$98 - $217

Train, bus  •  21 h 5 min

  1. Take the train from Winter Park Amtrak to Savannah Amtrak
  2. Take the bus from Savannah to Columbia
  3. Take the bus from Columbia to Greenville

$105 - $252

Train  •  21 h 27 min

  1. Take the train from Orlando Amtrak to Cary Amtrak
  2. Take the train from Cary Amtrak to Charlotte Amtrak
  3. Take the train from Charlotte Amtrak to Greenville Amtrak

$159 - $425

Drive  •  8 h 56 min

  1. Drive from Orlando Airport (MCO) to Greenville 547.3 miles

$50 - $80

What companies run services between Orlando Airport (MCO), USA and Greenville, SC, USA?

Southwest Airlines, American Airlines and two other airlines fly from Orlando Airport (MCO) to Greenville hourly. Alternatively, you can take a bus from Orlando Airport (MCO) to Greenville via Lynx Kissimmee Intermodal Station, Kissimmee, Fl, Orlando, Fl, Atlanta, Ga, and Greenville, Sc in around 15 h 1 min.

Airlines
American Airlines
Website
aa.com
Flights from Orlando to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$150 - $750
Flights from Orlando to Greenville/Spartanburg via Reagan Washington
Ave. Duration
5 h 16 min
When
Sunday
Estimated price
$190 - $850
Flights from Orlando to Charlotte
Ave. Duration
1 h 47 min
When
Every day
Estimated price
$170 - $700
Delta
Website
delta.com
Flights from Orlando to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 52 min
When
Every day
Estimated price
$140 - $750
Flights from Orlando to Charlotte via Atlanta
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$160 - $850
Southwest Airlines
Website
southwest.com
Flights from Orlando to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 58 min
When
Every day
Estimated price
$160 - $700
Frontier Airlines
Website
flyfrontier.com
Flights from Orlando to Charlotte
Ave. Duration
1 h 46 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$65 - $700
United Airlines
Website
united.com
Flights from Orlando to Greenville/Spartanburg via Washington Dulles
Ave. Duration
5 h 5 min
When
Every day
Estimated price
$190 - $900
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Charlotte Amtrak to Greenville Amtrak
Ave. Duration
2 h 9 min
Frequency
Twice daily
Estimated price
$30 - $70
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$50 - $80
Business Coach Seat
$45 - $70
Room
$160 - $230
Train from Winter Park Amtrak to Savannah Amtrak
Ave. Duration
5 h 27 min
Frequency
Twice daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $130
Business Coach Seat
$95 - $140
Room
$230 - $330
Train from Orlando Amtrak to Cary Amtrak
Ave. Duration
12 h 36 min
Frequency
Once daily
Estimated price
$90 - $260
Website
amtrak.com
Coach Seat
$90 - $140
Flexi Coach Seat
$160 - $230
Business Coach Seat
$180 - $260
Room
$370 - $550
Train from Cary Amtrak to Charlotte Amtrak
Ave. Duration
3 h 6 min
Frequency
Every 4 hours
Estimated price
$35 - $90
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$65 - $95
Business Coach Seat
$60 - $90
Room
$180 - $260
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Orlando, Fl to Atlanta, Ga
Ave. Duration
8 h 5 min
Frequency
Hourly
Estimated price
$45 - $120
Website
greyhound.com
Economy
$45 - $75
Flexible
$85 - $120
Bus from Atlanta, Ga to Greenville, Sc
Ave. Duration
3 h 40 min
Frequency
Hourly
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Savannah to Columbia
Ave. Duration
8 h 30 min
Frequency
Once daily
Estimated price
$27 - $70
Schedules at
southeasternstages.com
Bus from Columbia to Greenville
Ave. Duration
1 h 50 min
Frequency
Once daily
Estimated price
$22 - $35
Schedules at
southeasternstages.com
Bus from Atlanta, GA to Greenville
Ave. Duration
9 h 20 min
Frequency
Once daily
Estimated price
$35 - $70
Schedules at
southeasternstages.com

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Questions & Answers

How far is it from Orlando Airport (MCO) to Greenville?

The distance between Orlando Airport (MCO) and Greenville is 721 km. The road distance is 876 km.

What is the cheapest way to get from Orlando Airport (MCO) to Greenville?

The cheapest way to get from Orlando Airport (MCO) to Greenville is to drive which costs $50 - $80 and takes 8 h 56 min.

What is the fastest way to get from Orlando Airport (MCO) to Greenville?

The quickest way to get from Orlando Airport (MCO) to Greenville is to fly which takes 3 h 47 min and costs $170 - $800.

How long does it take to get from Orlando Airport (MCO) to Greenville?

It takes approximately 3 h 47 min to get from Orlando Airport (MCO) to Greenville, including transfers.