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How to get fromOpelousas to Mobileby bus, car, plane, bus (Greyhound, Flixbus) or bus (Flixbus)

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There are 6 ways to get from Opelousas to Mobile by bus, car, plane, bus (Greyhound, Flixbus), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Lafayette to Mobilebus bus Houston
    5h 13m
    $76–103

  2. Drive 258.1 mi

    cheapest
    1. Drive from Opelousas to Mobilecar car 258.1 mi
    4h 22m
    $48–68

  3. Fly to Mobile Regional Airport

    1. Fly from Lafayette Regional Airport (LFT) to Mobile Regional Airport (MOB)plane plane LFT - MOB
    7h 36m
    $76–383

  4. Bus via Baton Rouge

    1. Take the bus from Opelousas to Baton Rouge Bus Stationbus bus Greyhound 2221 / ...
    2. Take the bus from Baton Rouge Bus Station to Mobile Bus Stationbus bus Greyhound US0602 / ...
    6h 50m
    $60–158

  5. Bus via Govt EB at Greyhound Bus Station (Flixbus)

    1. Take the bus from Lafayette to Mobile Bus Stationbus bus FlixBus N2210
    7h 2m
    $51–98

  6. Fly to Pensacola International Airport, bus

    1. Fly from Lafayette Regional Airport (LFT) to Pensacola International Airport (PNS)plane plane LFT - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    8h 4m
    $121–548

Lafayette Regional Airport (LFT) to Mobile Regional Airport (MOB) flights

Calendar50Weekly Planes
Duration5h 14mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

What companies run services between Opelousas, LA, USA and Mobile, AL, USA?

Omnibus Express operates a bus from Lafayette to Mobile once daily. Tickets cost $65–90 and the journey takes 4h 49m. Alternatively, United Airlines, American Airlines, and Delta fly from Lafayette Regional Airport (LFT) to Mobile Regional Airport (MOB) every 4 hours.

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Bus operators

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Need to know: Greyhound

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