Rome2Rio

How to get fromOpelousas to Chicagoby plane, bus, train, bus (Greyhound, Flixbus) or car

Find Transport to Chicago

See all options

There are 8 ways to get from Opelousas to Chicago by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lafayette Regional Airport to Chicago Midway International Airport

    best
    1. Fly from Lafayette Regional Airport (LFT) to Chicago Midway International Airport (MDW)plane plane LFT - MDW
    6h 10m
    $113–518

  2. Fly Lafayette Regional Airport to Chicago O'Hare International Airport

    cheapest
    1. Fly from Lafayette Regional Airport (LFT) to Chicago O'Hare International Airport (ORD)plane plane LFT - ORD
    6h 9m
    $83–368

  3. Bus, train

    1. Take the bus from Opelousas to New Orleans Bus Stationbus bus Greyhound 2221 / ...
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train City of New Orleans
    25h 21m
    $166–298

  4. Bus

    1. Take the bus from Opelousas to Baton Rouge Bus Stationbus bus
    2. Take the bus from Baton Rouge Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    26h 26m
    $141–298

  5. Drive 920.6 mi

    1. Drive from Opelousas to Chicagocar car 920.6 mi
    16h 52m
    $168–243

  6. Bus to Louis Armstrong New Orleans International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Opelousas to New Orleans International Airportbus bus
    2. Fly from Louis Armstrong New Orleans International Airport (MSY) to Chicago Midway International Airport (MDW)plane plane MSY - MDW
    8h 28m
    $133–538

  7. Bus to Alexandria International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Opelousas to Boyce, LAbus bus
    2. Fly from Alexandria International Airport (AEX) to Chicago Midway International Airport (MDW)plane plane AEX - MDW
    8h 40m
    $161–599

  8. Bus to Louis Armstrong New Orleans International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Opelousas to New Orleans International Airportbus bus
    2. Fly from Louis Armstrong New Orleans International Airport (MSY) to Chicago O'Hare International Airport (ORD)plane plane MSY - ORD
    8h 44m
    $133–438

Lafayette Regional Airport (LFT) to Chicago Midway International Airport (MDW) flights

Calendar10Weekly Planes
Duration5h 39mAverage Duration
Ticket$100Cheapest Price
See schedules

Questions & Answers

What companies run services between Opelousas, LA, USA and Chicago, IL, USA?

Delta, United Airlines, and two other airlines fly from Lafayette Regional Airport (LFT) to Chicago Midway International Airport (MDW) once daily. Alternatively, you can take a vehicle from Opelousas to Chicago Bus Station via Opelousas, Baton Rouge Bus Station, and St Louis Bus Station in around 26h 26m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Where to next?

Trips from Opelousas

Trips to Chicago

Popular routes