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How to get fromOld Lyme to Ithacaby train, bus, car or plane

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There are 10 ways to get from Old Lyme to Ithaca by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Old Saybrook Amtrak Station to Ny Moynihan Train Hall At Penn StationtrainNortheast Regional
    2. Take the bus from New York, NY to Ithaca, NYbusOurBus
    8h 52m
    $35–314
  2. Train, bus via Syracuse

    1. Take the train from Old Saybrook Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
    2. Take the train from New York Penn Station to Syracusetrain
    3. Take the bus from Syracuse Bus Station to Ithacabus
    12h 2m
    $70–363
  3. Drive 278.4 mi

    1. Drive from Old Lyme to Ithacacar278.4 mi
    5h 48m
    $51–74
  4. Train to John F. Kennedy International Airport, fly to Ithaca Tompkins Regional Airport

    1. Take the train from Old Saybrook Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
    2. Fly from John F. Kennedy International Airport (JFK) to Ithaca Tompkins Regional Airport (ITH)planeJFK - ITH
    7h 42m
    $63–503
  5. Train, bus #2

    1. Take the train from Old Saybrook Amtrak Station to Ny Moynihan Train Hall At Penn StationtrainNortheast Regional
    2. Take the bus from New York Midtown to IthacabusFlixBus 2683 / ...
    9h 4m
    $50–314
  6. Train, bus via New Haven

    1. Take the train from Old Saybrook Amtrak Station to New Haventrain
    2. Take the train from New Haven to 125th Street - Harlemtrain
    3. Take the bus from New York, NY to Ithaca, NYbus
    9h 14m
    $42–302
  7. Bus

    1. Take the bus from Old Saybrook Trans Cntr to Asylum St @ Union Plbus921
    2. Take the bus from Hartford Union Station to Port Authority Bus Terminalbus
    3. Take the bus from New York to Ithacabus
    11h 28m
    $53–206
  8. Train to John F. Kennedy International Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the train from Old Saybrook Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
    2. Fly from John F. Kennedy International Airport (JFK) to Syracuse Hancock International Airport (SYR)planeJFK - SYR
    3. Take the bus from Syracuse Airport, NY to Ithaca, NYbus
    9h 2m
    $103–718
  9. Train, train to Laguardia Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the train from Old Saybrook Amtrak Station to Stamford Amtrak Stationtrain
    2. Take the train from Stamford to 125th Street - Harlemtrain
    3. Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)planeLGA - SYR
    4. Take the bus from Syracuse Airport, NY to Ithaca, NYbus
    9h 15m
    $102–745
  10. Train to Boston Logan Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the train from New London to Bostontrain
    2. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)planeBOS - SYR
    3. Take the bus from Syracuse Airport, NY to Ithaca, NYbus
    9h 5m
    $107–794

Old Lyme to Ithaca by bus and train

Calendar7Weekly Services
Duration12h 2mAverage Duration
Ticket$70Cheapest Price
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Questions & Answers

What companies run services between Old Lyme, CT, USA and Ithaca, NY, USA?

You can take a bus from Lyme St & Library Ln to Ithaca via Old Saybrook Train Station Bus Shelter, Old Saybrook Trans Cntr, Asylum St @ Union Pl, Hartford Union Station, Port Authority Bus Terminal, and New York in around 11h 28m.

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