Rome2Rio

How to get fromOhio to Tupeloby plane, bus (Amtrak, Greyhound), car, bus or bus (Greyhound)

Find Transport to Tupelo

See all options

There are 8 ways to get from Ohio to Tupelo by plane, bus (Amtrak, Greyhound), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Glenn Columbus International Airport to Tupelo Regional Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Tupelo Regional Airport (TUP)planeCMH - TUP
    5h 53m
    $125–637

  2. Drive 572.6 mi

    cheapest
    1. Drive from Columbus to Tupelocar572.6 mi
    10h 42m
    $105–151

  3. Bus via Louisville

    1. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus
    2. Take the bus from Louisville, KY to Nashvillebus
    3. Take the bus from Nashville Bus Station to Memphis Bus Stationbus
    4. Take the bus from Memphis Bus Station to Tupelobus
    15h 40m
    $121–272

  4. Fly Cleveland-Hopkins International Airport to Tupelo Regional Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Tupelo Regional Airport (TUP)planeCLE - TUP
    7h 39m
    $138–722

  5. Fly Covington to Tupelo Regional Airport

    1. Fly from Covington (CVG) to Tupelo Regional Airport (TUP)planeCVG - TUP
    8h 22m
    $140–774

  6. Bus to Detroit, fly to Memphis, bus

    1. Take the bus from Toledo to Dearbornbus
    2. Fly from Detroit (DTW) to Memphis (MEM)planeDTW - MEM
    3. Take the bus from Memphis Bus Station to Tupelobus
    9h 27m

  7. Bus (Greyhound)

    1. Take the bus from Columbus to Nashville Bus Stationbus
    2. Take the bus from Nashville Bus Station to Memphis Bus Stationbus
    3. Take the bus from Memphis Bus Station to Tupelobus
    18h 39m
    $139–399

  8. Bus via Atlanta (Greyhound)

    1. Take the bus from Columbus to Atlanta Bus StationbusGreyhound US0105
    2. Take the bus from Atlanta Bus Station to TupelobusGreyhound US0610
    24h 4m
    $158–315

John Glenn Columbus International Airport (CMH) to Tupelo Regional Airport (TUP) flights

Calendar19Weekly Planes
Duration7h 17mAverage Duration
Ticket$104Cheapest Price
See schedules

Questions & Answers

What companies run services between Ohio, USA and Tupelo, MS, USA?

Southwest Airlines, Corporate Flight Management Inc, and two other airlines fly from John Glenn Columbus International Airport (CMH) to Tupelo Regional Airport (TUP) 3 times a day. Alternatively, you can take a bus from Columbus - Downtown - Mound St to Tupelo via Louisville, KY, Nashville Bus Station, Memphis Bus Station, and Tupelo in around 15h 40m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Ohio

Trips to Tupelo

Popular routes