Rome2Rio

How to get fromOhio to Tupeloby plane, bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)

Find Transport to Tupelo

See all options

There are 9 ways to get from Ohio to Tupelo by plane, bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Glenn Columbus International Airport to Tupelo Regional Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Tupelo Regional Airport (TUP)plane plane CMH - TUP
    6h 10m
    $126–671

  2. Drive  572.7 mi

    cheapest
    1. Drive from Columbus to Tupelocar car 572.7 mi
    10h 46m
    $105–151

  3. Bus via Reading

    1. Take the bus from Columbus to Cincinnatibus bus
    2. Take the bus from Cincinnati Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    16h 29m
    $119–256

  4. Bus to Detroit, fly to Huntsville International Airport-Carl T Jones Field, drive

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane DTW - HSV
    3. Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar car
    7h 32m

  5. Fly Cleveland-Hopkins International Airport to Tupelo Regional Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Tupelo Regional Airport (TUP)plane plane CLE - TUP
    7h 40m
    $126–670

  6. Fly Covington to Tupelo Regional Airport

    1. Fly from Covington (CVG) to Tupelo Regional Airport (TUP)plane plane CVG - TUP
    8h 20m
    $128–772

  7. Bus to Detroit, fly to Memphis, bus

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Memphis (MEM)plane plane DTW - MEM
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    9h 24m

  8. Bus

    1. Take the bus from Columbus to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    17h 59m
    $133–210

  9. Bus via Atlanta (Greyhound)

    1. Take the bus from Columbus to Atlanta Bus Stationbus bus Greyhound US0105
    2. Take the bus from Atlanta Bus Station to Tupelobus bus Greyhound US0610
    24h 54m
    $174–263

John Glenn Columbus International Airport (CMH) to Tupelo Regional Airport (TUP) flights

Calendar30Weekly Planes
Duration6h 59mAverage Duration
Ticket$110Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Ohio to Tupelo.ExpandLaunch map view
  • Distance: 528.2 mi
  • Duration: 6h 10m

What companies run services between Ohio, USA and Tupelo, MS, USA?

Southwest Airlines, Corporate Flight Management Inc, and two other airlines fly from John Glenn Columbus International Airport (CMH) to Tupelo Regional Airport (TUP) 4 times a day. Alternatively, you can take a bus from Columbus to Tupelo via Columbus, Cincinnati, Cincinnati Bus Station, Nashville Bus Station, Memphis Bus Station, and Tupelo in around 16h 29m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There