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How to get fromOhio to Missouriby plane, bus (Greyhound), bus, train, or car

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There are 9 ways to get from Ohio to Missouri by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Glenn Columbus International Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    4h 5m
    $115–706

  2. Drive  656.4 mi

    cheapest
    1. Drive from Columbus to Kansas Citycar car 656.4 mi
    11h 2m
    $113–162

  3. Bus (Greyhound)

    1. Take the bus from Columbus to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus Greyhound US0180s / ...
    14h 25m
    $122–183

  4. Bus, train

    1. Take the bus from Columbus to Chicago Bus Stationbus bus FlixBus 2511 / ...
    2. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    16h 14m
    $289–456

  5. Bus, train via Toledo

    1. Take the bus from Columbus to Toledobus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Napervilletrain train
    4. Take the train from Naperville Amtrak Station to Kansas Citytrain train
    17h 44m
    $371–594

  6. Fly from Cleveland-Hopkins International Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    3h 55m
    $116–656

  7. Fly from Covington

    1. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    6h 33m
    $147–857

  8. Bus to Detroit, fly

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    5h 34m

  9. Bus, train #2

    1. Take the bus from Columbus to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the train from St. Louis to Kansas Citytrain train Missouri River Runner / ...
    16h 17m
    $227–353

Ohio to Missouri by bus (Greyhound)

Calendar21Weekly Buses
Duration14h 25mAverage Duration
Ticket$122Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ohio to Missouri.ExpandLaunch map view
  • Distance: 435.3 mi
  • Duration: 4h 5m

What companies run services between Ohio, USA and Missouri, USA?

Southwest Airlines and Delta fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Columbus to Kansas City Bus Station via St Louis Bus Station in around 14h 25m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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