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How to get fromOhio to Missouriby plane, bus (Flixbus, Greyhound), bus, train, car or bus (Greyhound)

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There are 9 ways to get from Ohio to Missouri by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Glenn Columbus International Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    4h
    $115–806

  2. Bus via New Paris

    cheapest
    1. Take the bus from Columbus - Mound St to Richmond, INbus bus
    2. Take the bus from Richmond Bsb, IN to Indianapolis, INbus bus
    3. Take the bus from Indianapolis Union Station to Kansas City Bus Stationbus bus
    15h 50m
    $77–224

  3. Bus via Indianapolis

    1. Take the bus from Columbus to Indianapolisbus bus FlixBus N2640 / ...
    2. Take the bus from Indianapolis Union Station to Kansas City Bus Stationbus bus Greyhound US0421D
    15h 4m
    $90–180

  4. Bus, train via Chicago

    1. Take the bus from Columbus - Mound St to Toledo Bus Stopbus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Napervilletrain train
    4. Take the train from Naperville Amtrak Station to Kansas Citytrain train
    17h 43m
    $123–361

  5. Drive 656.4 mi

    1. Drive from Columbus to Kansas Citycar car 656.4 mi
    11h 5m
    $120–173

  6. Fly from Cleveland-Hopkins International Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    3h 55m
    $146–906

  7. Bus to Detroit, fly

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    5h 41m

  8. Bus (Greyhound)

    1. Take the bus from Columbus to Indianapolis Union Stationbus bus Greyhound US0421 / ...
    2. Take the bus from Indianapolis Union Station to Kansas City Bus Stationbus bus Greyhound US0421D
    15h 30m
    $90–190

  9. Bus, train

    1. Take the bus from Columbus to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the train from St. Louis to Kansas Citytrain train Missouri River Runner / ...
    15h 57m
    $83–279

Ohio to Missouri by bus and foot

Calendar2Weekly Services
Duration15h 4mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

What companies run services between Ohio, USA and Missouri, USA?

Southwest Airlines flies from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL) 4 times a day. Alternatively, you can take a bus from Columbus to Kansas City Bus Station via Indianapolis and Indianapolis Union Station in around 15h 4m.

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