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How to get fromOhio to Iowaby bus, plane, bus (Flixbus, Greyhound), car, bus (Greyhound) or train

Find Transport to Iowa

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There are 10 ways to get from Ohio to Iowa by bus, plane, bus (Flixbus, Greyhound), car, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Detroit, fly to Des Moines

    best
    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    5h 23m
    $96–386

  2. Fly John Glenn Columbus International Airport to Quad City International Airport

    cheapest
    1. Fly from John Glenn Columbus International Airport (CMH) to Quad City International Airport (MLI)plane plane CMH - MLI
    6h 58m
    $64–385

  3. Bus

    1. Take the bus from Columbus to Chicago Bus Stationbus bus FlixBus N2640 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    15h 19m
    $106–184

  4. Drive 619.8 mi

    1. Drive from Columbus to Des Moinescar car 619.8 mi
    11h 26m
    $114–164

  5. Fly Dayton to Quad City International Airport

    1. Fly from Dayton (DAY) to Quad City International Airport (MLI)plane plane DAY - MLI
    7h 2m
    $74–464

  6. Fly Cleveland-Hopkins International Airport to Quad City International Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Quad City International Airport (MLI)plane plane CLE - MLI
    6h 46m
    $70–424

  7. Bus to Detroit, fly to Omaha

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Omaha (OMA)plane plane DTW - OMA
    5h 43m
    $214–1,025

  8. Fly Covington to Quad City International Airport

    1. Fly from Covington (CVG) to Quad City International Airport (MLI)plane plane CVG - MLI
    7h 18m
    $81–506

  9. Bus #2

    1. Take the bus from Columbus - Mound St to Chicagobus bus Columbus / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    15h 19m
    $96–188

  10. Bus, train

    1. Take the bus from Columbus - Mound St to Toledo Bus Stopbus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    16h 6m
    $141–282

Detroit (DTW) to Des Moines (DSM) flights

Calendar57Weekly Planes
Duration3h 30mAverage Duration
Ticket$53Cheapest Price
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Questions & Answers

What companies run services between Ohio, USA and Iowa, USA?

You can take a bus from Columbus to Des Moines via Chicago Bus Station and Des Moines in around 15h 19m. Alternatively, United Airlines, Delta, and American Airlines fly from Dayton (DAY) to Quad City International Airport (MLI) every 2 hours.

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