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How to get fromOhio to Iowaby plane, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound)

Find Transport to Iowa

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There are 10 ways to get from Ohio to Iowa by plane, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Glenn Columbus International Airport to Des Moines

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM)plane plane CMH - DSM
    5h 18m
    $169–924

  2. Fly Dayton to Quad City International Airport

    cheapest
    1. Fly from Dayton (DAY) to Quad City International Airport (MLI)plane plane DAY - MLI
    7h 29m
    $64–404

  3. Bus via Indianapolis

    1. Take the bus from Columbus to Indianapolisbus bus FlixBus 2511 / ...
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    14h 44m
    $107–201

  4. Drive 619.8 mi

    1. Drive from Columbus to Des Moinescar car 619.8 mi
    11h 26m
    $114–164

  5. Fly John Glenn Columbus International Airport to Omaha

    1. Fly from John Glenn Columbus International Airport (CMH) to Omaha (OMA)plane plane CMH - OMA
    5h 27m
    $187–933

  6. Bus to Detroit, fly to Des Moines

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    5h 17m
    $158–766

  7. Fly John Glenn Columbus International Airport to Quad City International Airport

    1. Fly from John Glenn Columbus International Airport (CMH) to Quad City International Airport (MLI)plane plane CMH - MLI
    7h 15m
    $69–415

  8. Bus to Detroit, fly to Omaha

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Omaha (OMA)plane plane DTW - OMA
    5h 37m
    $176–775

  9. Bus (Greyhound)

    1. Take the bus from Columbus to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    15h 10m
    $113–219

  10. Bus #2

    1. Take the bus from Columbus - Mound St to Chicagobus bus Columbus / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    15h 15m
    $96–198

John Glenn Columbus International Airport (CMH) to Des Moines (DSM) flights

Calendar122Weekly Planes
Duration5h 14mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

What companies run services between Ohio, USA and Iowa, USA?

Southwest Airlines, American Airlines, and two other airlines fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Columbus to Des Moines via Indianapolis, Indianapolis Union Station, and Des Moines in around 14h 44m.

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