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How to get fromOhio to Des Moinesby plane, bus (Flixbus, Greyhound), car, bus, bus (Greyhound) or train

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There are 10 ways to get from Ohio to Des Moines by plane, bus (Flixbus, Greyhound), car, bus, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Glenn Columbus International Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM)plane plane CMH - DSM
    5h 53m
    $84–434
  2. Bus

    1. Take the bus from Columbus to Chicago Bus Stationbus bus FlixBus N2640 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0155S
    17h 5m
    $99–185
  3. Drive 619.8 mi

    1. Drive from Columbus to Des Moinescar car 619.8 mi
    11h 26m
    $114–164
  4. Fly from Cleveland-Hopkins International Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM)plane plane CLE - DSM
    5h 28m
    $94–474
  5. Fly from Dayton

    1. Fly from Dayton (DAY) to Des Moines (DSM)plane plane DAY - DSM
    5h 49m
    $99–513
  6. Fly from Akron

    1. Fly from Akron (CAK) to Des Moines (DSM)plane plane CAK - DSM
    6h 2m
    $84–402
  7. Fly from Covington

    1. Fly from Covington (CVG) to Des Moines (DSM)plane plane CVG - DSM
    5h 51m
    $111–575
  8. Bus to Detroit, fly

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    5h 24m
    $97–381
  9. Bus #2

    1. Take the bus from Columbus - Mound St to Chicagobus bus Columbus / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0155S
    17h 5m
    $88–187
  10. Bus, train

    1. Take the bus from Columbus - Mound St to Toledo Bus Stopbus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    17h 52m
    $133–282

Ohio to Des Moines by bus

Calendar7Weekly Buses
Duration17h 5mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

What companies run services between Ohio, USA and Des Moines, IA, USA?

Southwest Airlines, United Airlines, and two other airlines fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Columbus to Des Moines via Chicago Bus Station in around 17h 5m.

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