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How to get fromOhio to Des Moinesby plane, bus (Flixbus, Greyhound), car, bus, bus (Greyhound) or train

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There are 10 ways to get from Ohio to Des Moines by plane, bus (Flixbus, Greyhound), car, bus, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Glenn Columbus International Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM)plane plane CMH - DSM
    5h 53m
    $89–444

  2. Bus #2

    cheapest
    1. Take the bus from Columbus - Mound St to Chicagobus bus Columbus / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    15h 14m
    $73–157

  3. Bus

    1. Take the bus from Columbus to Chicago Bus Stationbus bus FlixBus N2640 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    15h 14m
    $90–150

  4. Drive 619.8 mi

    1. Drive from Columbus to Des Moinescar car 619.8 mi
    11h 26m
    $114–164

  5. Fly from Cleveland-Hopkins International Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM)plane plane CLE - DSM
    5h 38m
    $100–474

  6. Fly from Dayton

    1. Fly from Dayton (DAY) to Des Moines (DSM)plane plane DAY - DSM
    5h 45m
    $114–623

  7. Fly from Akron

    1. Fly from Akron (CAK) to Des Moines (DSM)plane plane CAK - DSM
    6h 25m
    $84–392

  8. Fly from Covington

    1. Fly from Covington (CVG) to Des Moines (DSM)plane plane CVG - DSM
    6h 25m
    $116–625

  9. Bus to Detroit, fly

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    5h 34m

  10. Bus, train

    1. Take the bus from Columbus - Mound St to Toledo Bus Stopbus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    16h 1m
    $88–259

Ohio to Des Moines by bus

Calendar13Weekly Buses
Duration15h 14mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

What companies run services between Ohio, USA and Des Moines, IA, USA?

Southwest Airlines, Delta, and two other airlines fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Columbus to Des Moines via Chicago Bus Station in around 15h 14m.

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