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How to get fromOhio to Des Moinesby plane, bus (Greyhound), car, bus, bus (Flixbus, Greyhound), or train

Find Transport to Des Moines

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There are 8 ways to get from Ohio to Des Moines by plane, bus (Greyhound), car, bus, bus (Flixbus, Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Glenn Columbus International Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM)plane plane CMH - DSM
    5h 28m
    $100–506

  2. Bus (Greyhound)

    1. Take the bus from Columbus to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    15h
    $105–166

  3. Drive  620.1 mi

    1. Drive from Columbus to Des Moinescar car 620.1 mi
    11h 27m
    $114–164

  4. Fly from Cleveland-Hopkins International Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM)plane plane CLE - DSM
    5h 13m
    $100–496

  5. Fly from Covington

    1. Fly from Covington (CVG) to Des Moines (DSM)plane plane CVG - DSM
    5h 48m
    $112–577

  6. Bus to Detroit, fly

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    5h 23m

  7. Bus #2

    1. Take the bus from Columbus to Chicago Bus Stationbus bus FlixBus 2511 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    15h
    $109–166

  8. Bus, train

    1. Take the bus from Columbus to Toledobus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    17h 49m
    $259–431

Ohio to Des Moines by bus (Greyhound)

Calendar7Weekly Buses
Duration15hAverage Duration
Ticket$105Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ohio to Des Moines.ExpandLaunch map view
  • Distance: 591.9 mi
  • Duration: 5h 28m

What companies run services between Ohio, USA and Des Moines, IA, USA?

Southwest Airlines, Delta, and two other airlines fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Columbus to Des Moines via Indianapolis Union Station in around 15h.

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