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How to get fromOhio to Des Moinesby plane, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound)

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There are 10 ways to get from Ohio to Des Moines by plane, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Glenn Columbus International Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM)plane plane CMH - DSM
    5h 18m
    $169–924

  2. Bus #2

    cheapest
    1. Take the bus from Columbus - Mound St to Chicagobus bus Columbus / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    15h 10m
    $88–187

  3. Bus via Indianapolis

    1. Take the bus from Columbus to Indianapolisbus bus FlixBus 2511 / ...
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    14h 39m
    $99–190

  4. Drive 619.8 mi

    1. Drive from Columbus to Des Moinescar car 619.8 mi
    11h 26m
    $114–164

  5. Fly from Cleveland-Hopkins International Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM)plane plane CLE - DSM
    5h 8m
    $180–924

  6. Fly from Dayton

    1. Fly from Dayton (DAY) to Des Moines (DSM)plane plane DAY - DSM
    6h 7m
    $159–923

  7. Fly from Covington

    1. Fly from Covington (CVG) to Des Moines (DSM)plane plane CVG - DSM
    5h 40m
    $181–1,025

  8. Bus to Detroit, fly

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    5h 18m
    $158–766

  9. Fly from Akron

    1. Fly from Akron (CAK) to Des Moines (DSM)plane plane CAK - DSM
    5h 53m
    $123–607

  10. Bus (Greyhound)

    1. Take the bus from Columbus to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    15h 5m
    $105–208

Ohio to Des Moines by bus and foot

Calendar7Weekly Services
Duration14h 39mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

What companies run services between Ohio, USA and Des Moines, IA, USA?

Southwest Airlines, American Airlines, and two other airlines fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Columbus to Des Moines via Indianapolis and Indianapolis Union Station in around 14h 39m.

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