There are 7 ways to get from Ocean Isle Beach to Key West by taxi, plane, bus, train, shuttle, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Myrtle Beach, fly
best- Take the taxi from Ocean Isle Beach to Myrtle Beach (MYR)taxi
- Fly from Myrtle Beach (MYR) to Key West International Airport (EYW)plane MYR - EYW
4h 38m$231–704Drive to Albert J. Ellis Airport, fly
cheapest- Drive from Ocean Isle Beach to Albert J. Ellis Airport (OAJ)car
- Fly from Albert J. Ellis Airport (OAJ) to Key West International Airport (EYW)plane OAJ - EYW
7h 21m$129–589Taxi, bus, train, shuttle
- Take the taxi from Ocean Isle Beach to Myrtle Beach Bus Stationtaxi
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Miami Amtrak Stationtrain
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
25h 34m$381–534Taxi, bus
- Take the taxi from Ocean Isle Beach to Whiteville Columbus County Transittaxi
- Take the bus from Whiteville Columbus County Transit to Fayetteville Bus Stationbus
- Take the bus from Fayetteville Bus Station to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
25h 54m$281–508Drive 870.3 mi
- Drive from Ocean Isle Beach to Key Westcar 870.3 mi
16h 15m$159–230Taxi to Wilmington International Airport, fly
- Take the taxi from Ocean Isle Beach to Wilmington International Airport (ILM)taxi
- Fly from Wilmington International Airport (ILM) to Key West International Airport (EYW)plane ILM - EYW
6h$255–733Taxi, bus, train
- Take the taxi from Ocean Isle Beach to Myrtle Beach Bus Stationtaxi
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
25h 46m$229–384
Myrtle Beach (MYR) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Ocean Isle Beach to Key West is to drive which costs $150 - $230 and takes 16h 15m.
The fastest way to get from Ocean Isle Beach to Key West is to taxi and fly which takes 4h 38m and costs $230 - $750.
The distance between Ocean Isle Beach and Key West is 698 miles. The road distance is 875.4 miles.
The best way to get from Ocean Isle Beach to Key West without a car is to taxi and bus and train and shuttle which takes 25h 34m and costs $380 - $550.
It takes approximately 4h 38m to get from Ocean Isle Beach to Key West, including transfers.
Yes, the driving distance between Ocean Isle Beach to Key West is 875 miles. It takes approximately 16h 15m to drive from Ocean Isle Beach to Key West.
There are 943+ hotels available in Key West.
What companies run services between Ocean Isle Beach, NC, USA and Key West, FL, USA?
There is no direct connection from Ocean Isle Beach to Key West. However, you can take the taxi to Myrtle Beach (MYR) airport, fly to Key West International Airport (EYW), then take the taxi to Key West. Alternatively, you can take the taxi to Myrtle Beach Bus Station, take the bus to Charleston Bus Station, walk to Charleston Amtrak Station, take the train to Miami Amtrak Station, walk to Metrorail Transfer Station, take the train to Miami Airport Station, walk to Miami, Airport Intermodal Station, take the vehicle to Miami International Airport, walk to Miami, FL - International Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, then take the bus to N Roosevelt & George Street.
- Website
- delta.com
Flights from Myrtle Beach to Key West International Airport via Atlanta
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $100–550
Flights from Wilmington International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $110–600
Flights from Albert J. Ellis Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $110–600
- Website
- aa.com
Flights from Myrtle Beach to Key West International Airport via Charlotte
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $100–550
Flights from Wilmington International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $100–550
Flights from Albert J. Ellis Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 9m
- When
- Every day
- Estimated price
- $100–550
- Website
- spirit.com
Flights from Myrtle Beach to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 4h 21m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charleston Amtrak Station to Miami Amtrak Station
- Ave. Duration
- 14h 3m
- Frequency
- Once daily
- Estimated price
- $85–180
- Website
- https://www.amtrak.com/home.html
Train from Charleston Amtrak Station to Hollywood Amtrak Station
- Ave. Duration
- 13h 25m
- Frequency
- Once daily
- Estimated price
- $80–200
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $12–14
- Website
- https://www.greyhound.com/
Bus from Whiteville Columbus County Transit to Fayetteville Bus Station
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $25–55
- Website
- https://www.greyhound.com/
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $28–50
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–29
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Fayetteville Bus Station to Orlando Bus Station
- Ave. Duration
- 9h 55m
- Frequency
- 5 times a week
- Estimated price
- $70–210
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $28–50
- Schedules at
- flixbus.com
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Ave. Duration
- 1h 1m
- Estimated price
- $110–170
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide







