There are 4 ways to get from OFallon to Louisville by plane, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Louisville International Airport
best- Fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF)plane STL - SDF
5h 1m$162–813Drive 291.1 mi
cheapest- Drive from OFallon to Louisvillecar 291.1 mi
4h 52m$54–77Bus
- Take the bus from St Louis Bus Station to Evansville Bus Stationbus Greyhound US0185
- Take the bus from Evansville, IN to Louisville, KYbus Evansville
8h 44m$115–168Fly to Blue Grass Airport, drive
- Fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX)plane STL - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
5h 18m$254–1,279
Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from OFallon to Louisville is to drive which costs $50 - $80 and takes 4h 52m.
The fastest way to get from OFallon to Louisville is to drive which takes 4h 52m and costs $50 - $80.
The distance between OFallon and Louisville is 281 miles. The road distance is 292.8 miles.
The best way to get from OFallon to Louisville without a car is to bus which takes 8h 44m and costs $110 - $170.
It takes approximately 5h 1m to get from OFallon to Louisville, including transfers.
The best way to get from OFallon to Louisville is to fly which takes 5h 1m and costs $160 - $850. Alternatively, you can bus, which costs $110 - $170 and takes 8h 44m.
Louisville is 1h ahead of OFallon. It is currently 9:20 AM in OFallon and 10:20 AM in Louisville.
Yes, the driving distance between OFallon to Louisville is 293 miles. It takes approximately 4h 52m to drive from OFallon to Louisville.
There are 600+ hotels available in Louisville.
What companies run services between OFallon, MO, USA and Louisville, KY, USA?
Southwest Airlines, United Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF) hourly. Alternatively, you can take a vehicle from OFallon to Louisville, KY via LAMBERT AIRPORT TERMINAL #1 station, CIVIC CENTER station, St Louis Bus Station, and Evansville, IN in around 8h 44m.
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $160–900
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $150–850
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $230–1,300
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Minneapolis
- Ave. Duration
- 5h 5m
- When
- Saturday
- Estimated price
- $290–1,500
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $220–1,300
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $130–800
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $190–1,200
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 3m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–800
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $240–1,300
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $190–1,200
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 5m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $110–750
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- $120–750
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Evansville Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- $27–50
- Website
- https://www.greyhound.com/
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Evansville, IN to Louisville, KY
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide





