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How to get fromOFallon to Buffaloby plane, train (Amtrak), bus (Greyhound), car, shuttle or bus

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There are 8 ways to get from OFallon to Buffalo by plane, train (Amtrak), bus (Greyhound), car, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF)planeSTL - BUF
    5h 39m
    $335–1,640

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Columbus Bus StationbusGreyhound US0421
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Buffalo, NYbusCinncinati,OH-Buffalo
    20h 3m
    $132–250

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union StationtrainLincoln Service / ...
    2. Take the train from Chicago Union Station to Buffalo Depew StationtrainLake Shore Limited
    19h 33m
    $157–598

  4. Drive 762 mi

    1. Drive from OFallon to Buffalocar762 mi
    12h 55m
    $140–201

  5. Fly to Toronto Pearson International Airport, shuttle

    1. Fly from Lambert–St. Louis International Airport (STL) to Toronto Pearson International Airport (YYZ)planeSTL - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle
    6h 10m
    $405–950

  6. Fly to Toronto Island Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Toronto Island Airport (YTZ)planeSTL - YTZ
    2. Take the bus from Toronto to Buffalobus
    8h 38m
    $472–1,223

  7. Fly to Rochester, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Rochester (ROC)planeSTL - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus
    7h 28m
    $215–995

  8. Bus via Pittsburgh

    1. Take the bus from St Louis Bus Station to Pittsburgh Intermodal StationbusGreyhound US0421
    2. Take the bus from Pittsburgh to BuffalobusFab510
    24h 20m
    $151–402

Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF) flights

Calendar101Weekly Planes
Duration5h 4mAverage Duration
Ticket$284Cheapest Price
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Questions & Answers

What companies run services between OFallon, MO, USA and Buffalo, NY, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a vehicle from OFallon to Buffalo via LAMBERT AIRPORT TERMINAL #1 station, CIVIC CENTER station, St. Louis, Chicago Union Station, and Buffalo Depew Station in around 19h 33m.

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