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How to get fromNyon to Sienaby train (Trenitalia), bus, car, plane, or train

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There are 9 ways to get from Nyon to Siena by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Lausanne to Domodossolatrain train Ec
    2. Take the train from Domodossola to Milano Centraletrain train Ec
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    10h 16m
    €150–424

  2. Bus

    cheapest
    1. Take the bus from Nyon to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    11h 48m
    €51–66

  3. Drive 667.4 km

    1. Drive from Nyon to Sienacar car 667.4 km
    7h 35m
    €116–167

  4. Fly Geneva International Airport to Florence Peretola Airport, train

    1. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane plane GVA - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    8h 6m
    €113–300

  5. Train via Locarno

    1. Take the train from Nyon to Locarnotrain train Ic
    2. Take the train from Locarno to Milano Centraletrain train
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    11h 40m
    €219–649

  6. Bus via Aosta

    1. Take the bus from Geneva to Aostabus bus FlixBus N504 / ...
    2. Take the bus from Aosta to Sienabus bus N597
    14h 32m
    €69–161

  7. Fly Geneva International Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Geneva International Airport (GVA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane GVA - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 1m
    €110–275

  8. Train to Zurich Airport, fly to Florence Peretola Airport, train

    1. Take the train from Nyon to Zürich Flughafentrain train
    2. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 42m
    €207–535

  9. Fly Geneva International Airport to Fiumicino International Airport, train

    1. Fly from Geneva International Airport (GVA) to Fiumicino International Airport (FCO)plane plane GVA - FCO
    2. Take the train from Roma Termini to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 30m
    €113–335

Nyon to Siena by train

Calendar4Weekly Trains
Duration10h 16mAverage Duration
Ticket€150Cheapest Price
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Questions & Answers

Map of how to get from Nyon to Siena.ExpandLaunch map view
  • Distance: 739.4 km
  • Duration: 10h 16m

What companies run services between Nyon, Switzerland and Siena, Italy?

You can take a train from Nyon to Siena via Lausanne, Domodossola, Milano Centrale, and Firenze S.M.N. in around 10h 16m. Alternatively, you can take a bus from Nyon to Siena via Florence Villa Constanza Bus Station in around 11h 48m.

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