There are 8 ways to get from Nyon to Siena by bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Bologna
best- Take the bus from Nyon to Bolognabus
- Take the bus from Bologna to Sienabus Bologna - Siena / ...
10h 32m€48–67Train, bus
- Take the train from Nyon to Brigtrain
- Take the train from Domodossola to Milano Centraletrain
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
10h 43m€112–291Drive 667.6 km
- Drive from Nyon to Sienacar 667.6 km
7h 34m€115–166Fly Geneva International Airport to Florence Peretola Airport, train
- Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane GVA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 17m€99–270Bus
- Take the bus from Nyon to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus N528 / ...
12h 5m€51–84Train to Zurich Airport, fly to Florence Peretola Airport, train
- Take the train from Nyon to Zürich Flughafentrain
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane ZRH - FLR
- Take the train from Firenze S.M.N. to Sienatrain
9h 7m€190–529Fly Geneva International Airport to Venice Marco Polo Airport, train
- Fly from Geneva International Airport (GVA) to Venice Marco Polo Airport (VCE)plane GVA - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
9h 32m€94–310Fly Geneva International Airport to Fiumicino International Airport, train
- Fly from Geneva International Airport (GVA) to Fiumicino International Airport (FCO)plane GVA - FCO
- Take the train from Roma Termini to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
9h 5m€97–310
Nyon to Siena by bus
Questions & Answers
The cheapest way to get from Nyon to Siena is to bus via Bologna which costs €45 - €70 and takes 10h 32m.
The fastest way to get from Nyon to Siena is to drive which takes 7h 34m and costs €110 - €170.
No, there is no direct bus from Nyon to Siena. However, there are services departing from Nyon and arriving at Siena via Bologna. The journey, including transfers, takes approximately 10h 32m.
The distance between Nyon and Siena is 737 km. The road distance is 667.6 km.
The best way to get from Nyon to Siena without a car is to bus via Bologna which takes 10h 32m and costs €45 - €70.
It takes approximately 10h 32m to get from Nyon to Siena, including transfers.
Nyon to Siena bus services, operated by Sellitto, depart from Nyon station.
Nyon to Siena bus services, operated by Sellitto, arrive at Bologna station.
Yes, the driving distance between Nyon to Siena is 668 km. It takes approximately 7h 34m to drive from Nyon to Siena.
There are 2409+ hotels available in Siena.
What companies run services between Nyon, Switzerland and Siena, Italy?
You can take a bus from Nyon to Siena via Bologna in around 10h 32m.
- Website
- swiss.com
Flights from Geneva International Airport to Florence Peretola Airport via Zurich Airport
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €75–190
Flights from Geneva International Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- €75–220
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €80–290
Flights from Geneva International Airport to Venice Marco Polo Airport via Zurich Airport
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €80–300
Flights from Geneva International Airport to Fiumicino International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €60–180
- Website
- ita-airways.com
Flights from Geneva International Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- €75–220
Flights from Geneva International Airport to Florence Peretola Airport via Zurich Airport
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- €75–190
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €80–290
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €130–650
Flights from Geneva International Airport to Fiumicino International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €60–180
- Website
- easyjet.com
Flights from Geneva International Airport to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €30–170
Flights from Geneva International Airport to Fiumicino International Airport
- Ave. Duration
- 1h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €35–150
Flights from Geneva International Airport to Fiumicino International Airport via Nice
- Ave. Duration
- 3h 40m
- When
- Friday
- Estimated price
- €35–150
- Website
- lufthansa.com
Flights from Geneva International Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €150–750
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- €130–650
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Nyon to Brig
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- €60–180
- Website
- https://www.sbb.ch/en
Train from Nyon to Zürich Flughafen
- Ave. Duration
- 3h 14m
- Frequency
- Hourly
- Estimated price
- €90–260
- Website
- https://www.sbb.ch/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Domodossola to Milano Centrale
- Ave. Duration
- 1h 42m
- Frequency
- Every 2 hours
- Estimated price
- €8–11
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €45–85
- Schedules at
- trenitalia.com
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €35–70
- Schedules at
- trenitalia.com
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- Every 30 minutes
- Estimated price
- €35–75
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- €26–60
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €12–21
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 40m
- Frequency
- 5 times a day
- Estimated price
- €30–60
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once a week
- Estimated price
- €30–65
- Website
- https://www.italotreno.it/en
- Phone
- +39 0824 46304
- info@sellitto.com
- Website
- sellitto.com
Bus from Nyon to Bologna
- Ave. Duration
- 7h 45m
- Frequency
- Twice a week
- Estimated price
- €35–50
- Schedules at
- sellitto.com
Bus from Nyon to Florence Villa Constanza Bus Station
- Ave. Duration
- 10h
- Frequency
- Once a week
- Estimated price
- €45–60
- Schedules at
- sellitto.com
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Bologna to Siena
- Ave. Duration
- 2h 20m
- Frequency
- Hourly
- Estimated price
- €9–18
- Website
- https://www.itabus.it/en/home
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Bologna to Siena
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- €11–20
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €4–8
- Website
- https://www.flixbus.co.uk
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
- Phone
- +39 0827 34 117
- info@gruppodimaio.it
- Website
- gruppodimaio.it
Bus from Nyon to Florence Villa Constanza Bus Station
- Ave. Duration
- 10h 15m
- Frequency
- Twice a week
- Estimated price
- €55–80
- Schedules at
- gruppodimaio.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide







































