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How to get fromNyon to Sienaby train (Trenitalia), bus, car, plane or train

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There are 9 ways to get from Nyon to Siena by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Lausanne to Domodossolatrain train Ec
    2. Take the train from Domodossola to Rho Fiera Milanotrain train
    3. Take the train from Milano Rogoredo to Bologna centraletrain train
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    10h 30m
    €131–397

  2. Bus via Parma

    cheapest
    1. Take the bus from Nyon to Parmabus bus
    2. Take the bus from Parma to Sienabus bus N551 / ...
    11h 10m
    €49–69

  3. Drive 667.6 km

    1. Drive from Nyon to Sienacar car 667.6 km
    7h 34m
    €115–166

  4. Fly Geneva International Airport to Florence Peretola Airport, train

    1. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane plane GVA - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    8h 17m
    €99–270

  5. Train, bus

    1. Take the train from Nyon to Brigtrain train
    2. Take the train from Domodossola to Milano Centraletrain train
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    10h 43m
    €112–290

  6. Bus

    1. Take the bus from Nyon to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    12h 5m
    €51–84

  7. Train to Zurich Airport, fly to Florence Peretola Airport, train

    1. Take the train from Nyon to Zürich Flughafentrain train
    2. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 7m
    €190–528

  8. Fly Geneva International Airport to Venice Marco Polo Airport, train

    1. Fly from Geneva International Airport (GVA) to Venice Marco Polo Airport (VCE)plane plane GVA - VCE
    2. Take the train from Venezia Mestre to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 32m
    €94–313

  9. Fly Geneva International Airport to Fiumicino International Airport, train

    1. Fly from Geneva International Airport (GVA) to Fiumicino International Airport (FCO)plane plane GVA - FCO
    2. Take the train from Roma Termini to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 5m
    €97–310

Nyon to Siena by train

Calendar34Weekly Trains
Duration10h 30mAverage Duration
Ticket€131Cheapest Price
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Questions & Answers

What companies run services between Nyon, Switzerland and Siena, Italy?

You can take a train from Nyon to Siena via Lausanne, Domodossola, Rho Fiera Milano, Milano Rogoredo, Bologna Centrale, and Firenze S.M.N. in around 10h 30m. Alternatively, you can take a bus from Nyon to Siena via Parma in around 11h 10m.

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