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How to get fromNyon to Sienaby train (Trenitalia), bus, car, plane, or train

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There are 10 ways to get from Nyon to Siena by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Lausanne

    best
    1. Take the train from Lausanne to Domodossolatrain train Ec
    2. Take the train from Domodossola to Milano Centraletrain train Re4
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    10h 9m
    €128–361

  2. Bus

    cheapest
    1. Take the bus from Nyon to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    11h 41m
    €50–82

  3. Drive 667.4 km

    1. Drive from Nyon to Sienacar car 667.4 km
    7h 35m
    €118–170

  4. Fly Geneva International Airport to Florence Peretola Airport, train

    1. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane plane GVA - FLR
    2. Take the train from Firenze Rifredi to Sienatrain train
    7h 55m
    €117–299

  5. Train

    1. Take the train from Nyon to Brigtrain train
    2. Take the train from Domodossola to Rho Fiera Milanotrain train Re4
    3. Take the train from Rho-Fiera Milano to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    10h 43m
    €139–336

  6. Bus via Turin

    1. Take the bus from Nyon to Turin Corso Vittorio Emanuele IIbus bus
    2. Take the bus from Turin to Sienabus bus N597 / ...
    13h 55m
    €53–97

  7. Fly Geneva International Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Geneva International Airport (GVA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane GVA - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 51m
    €110–318

  8. Train to Zurich Airport, fly to Florence Peretola Airport, train

    1. Take the train from Nyon to Zürich Flughafentrain train
    2. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    3. Take the train from Firenze Rifredi to Sienatrain train
    8h 30m
    €220–557

  9. Fly Geneva International Airport to Fiumicino International Airport, train

    1. Fly from Geneva International Airport (GVA) to Fiumicino International Airport (FCO)plane plane GVA - FCO
    2. Take the train from Roma Termini to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 16m
    €111–320

  10. Train to Lyon–Saint Exupéry Airport, fly to Florence Peretola Airport, train

    1. Take the train from Bellegarde to Lyon Part Dieutrain train
    2. Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane plane LYS - FLR
    3. Take the train from Firenze Rifredi to Sienatrain train
    9h 18m
    €144–390

Nyon to Siena by train

Calendar33Weekly Trains
Duration10h 9mAverage Duration
Ticket€128Cheapest Price
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Questions & Answers

Map of how to get from Nyon to Siena.ExpandLaunch map view
  • Distance: 739.2 km
  • Duration: 10h 9m

What companies run services between Nyon, Switzerland and Siena, Italy?

You can take a train from Nyon to Siena via Lausanne, Domodossola, Milano Centrale, and Firenze S.M.N. in around 10h 9m. Alternatively, you can take a bus from Nyon to Siena via Florence Villa Constanza Bus Station in around 11h 41m.

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