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How to get fromNyon to Sienaby train (Trenitalia), bus, car, plane, or train

Find Transport to Siena

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There are 8 ways to get from Nyon to Siena by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Bologna

    best
    1. Take the train from Lausanne to Domodossolatrain train Ec
    2. Take the train from Domodossola to Rho-Fiera Milanotrain train Re
    3. Take the train from Milano Rogoredo to Bologna centraletrain train
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    10h 49m
    €138–245

  2. Bus

    cheapest
    1. Take the bus from Nyon to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 1518 / ...
    11h 50m
    €51–64

  3. Drive  667.4 km

    1. Drive from Nyon to Sienacar car 667.4 km
    7h 35m
    €121–174

  4. Fly Geneva International Airport to Florence Peretola Airport, train

    1. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane plane GVA - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    8h 1m
    €113–294

  5. Train

    1. Take the train from Nyon to Locarnotrain train Ic
    2. Take the train from Locarno to Milano Centraletrain train
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    11h 44m
    €231–399

  6. Bus via Aosta

    1. Take the bus from Geneva to Aostabus bus FlixBus 1404 / ...
    2. Take the bus from Aosta to Sienabus bus N597
    14h 32m
    €73–157

  7. Train to Zurich Airport, fly to Florence Peretola Airport, train

    1. Take the train from Nyon to Zürich Flughafentrain train
    2. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 42m
    €206–473

  8. Fly Geneva International Airport to Fiumicino International Airport, train

    1. Fly from Geneva International Airport (GVA) to Fiumicino International Airport (FCO)plane plane GVA - FCO
    2. Take the train from Roma Termini to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 31m
    €102–303

Nyon to Siena by train

Calendar33Weekly Trains
Duration10h 49mAverage Duration
Ticket€138Cheapest Price
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Comparing Your Travel Options

Map of how to get from Nyon to Siena.ExpandLaunch map view
  • Distance: 737.9 km
  • Duration: 10h 49m

What companies run services between Nyon, Switzerland and Siena, Italy?

You can take a train from Nyon to Siena via Lausanne, Domodossola, Milano Rogoredo, Bologna Centrale, and Firenze S.M.N. in around 10h 49m. Alternatively, you can take a bus from Nyon to Siena via Florence Villa Constanza Bus Station in around 11h 50m.

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