There are 8 ways to get from Notre Dame to St. Louis by plane, train (Amtrak), bus (Greyhound), car, train, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from South Bend
best- Fly from South Bend (SBN) to Lambert–St. Louis International Airport (STL)plane SBN - STL
4h 32m$162–976Bus
cheapest- Take the bus from South Bend, IN to Chicagobus Columbus / ...
- Take the bus from Chicago Bus Station to St Louis Bus Stationbus FlixBus N2521 / ...
9h 3m$55–125Train (Amtrak)
- Take the train from South Bend Station to Chicago Union Stationtrain Lake Shore Limited / ...
- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
8h 3m$69–174Bus via Indianapolis
- Take the bus from South Street Station - South Bend to Indianapolis Union Stationbus South Bend
- Take the bus from Indianapolis Union Station to St Louis Bus Stationbus Greyhound US0421 / ...
8h 8m$82–130Drive 362.1 mi
- Drive from Notre Dame to St. Louiscar 362.1 mi
6h 10m$67–96Train to Chicago O'Hare International Airport, fly
- Take the train from South Bend Airport to Van Buren St.train
- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
6h 11m$277–596Train to Chicago Midway International Airport, fly
- Take the train from South Bend Airport to Van Buren St.train
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
5h 56m$137–796Train via South Bend Airport
- Take the train from South Bend Airport to Van Buren St.train Westbound to Chicago / ...
- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
8h 18m$70–151
South Bend (SBN) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Notre Dame to St. Louis is to drive which costs $65 - $100 and takes 6h 10m.
The fastest way to get from Notre Dame to St. Louis is to fly which takes 4h 32m and costs $160 - $1,000.
The distance between Notre Dame and St. Louis is 317 miles. The road distance is 364.2 miles.
The best way to get from Notre Dame to St. Louis without a car is to train which takes 8h 3m and costs $65 - $180.
It takes approximately 4h 32m to get from Notre Dame to St. Louis, including transfers.
The best way to get from Notre Dame to St. Louis is to fly which takes 4h 32m and costs $160 - $1,000. Alternatively, you can train, which costs $65 - $180 and takes 8h 3m, you could also bus via Indianapolis, which costs $80 - $130 and takes 8h 8m.
St. Louis is 1h behind Notre Dame. It is currently 2:37 AM in Notre Dame and 1:37 AM in St. Louis.
Yes, the driving distance between Notre Dame to St. Louis is 364 miles. It takes approximately 6h 10m to drive from Notre Dame to St. Louis.
There are 345+ hotels available in St. Louis.
What companies run services between Notre Dame, IN, USA and St. Louis, MO, USA?
United Airlines, Delta, and American Airlines fly from South Bend (SBN) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a vehicle from Notre Dame to St. Louis via South Bend Station and Chicago Union Station in around 8h 3m.
- Website
- united.com
Flights from South Bend to Lambert–St. Louis International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $140–950
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $70–550
- Website
- aa.com
Flights from South Bend to Lambert–St. Louis International Airport via Charlotte
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $270–1,400
Flights from South Bend to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 16m
- When
- Every day
- Estimated price
- $320–1,500
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $70–550
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $100–750
- Website
- delta.com
Flights from South Bend to Lambert–St. Louis International Airport via Minneapolis
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $230–1,200
Flights from South Bend to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 6h 44m
- When
- Every day
- Estimated price
- $260–1,300
Flights from South Bend to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 7h 38m
- When
- Tuesday and Wednesday
- Estimated price
- $180–1,100
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $70–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from South Bend Station to Chicago Union Station
- Ave. Duration
- 2h 5m
- Frequency
- 3 times a day
- Estimated price
- $18–45
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $35–110
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from South Bend Airport to Van Buren St.
- Ave. Duration
- 2h 1m
- Frequency
- Every 2 hours
- Estimated price
- $13–15
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $13–15
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from South Street Station - South Bend to Indianapolis Union Station
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- https://ridewithmiller.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $30–55
- Website
- https://www.greyhound.com/
Bus from South Bend, IN to Chicago
- Ave. Duration
- 2h 10m
- Frequency
- Twice daily
- Estimated price
- $16–24
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from South Bend, IN to Chicago
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $8–45
- Website
- https://baronsbus.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 6h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide













