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How to get fromNorthbrook to St. Louisby train, bus, plane, train (Amtrak), bus (Flixbus), car or subway

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There are 6 ways to get from Northbrook to St. Louis by train, bus, plane, train (Amtrak), bus (Flixbus), car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus to Chicago O'Hare International Airport, fly

    best
    1. Take the train from Northbrook to Edgebrooktrain train
    2. Take the bus from Lehigh & Devon to Jefferson Park Transit Centerbus bus
    3. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    3h 57m
    $270–615

  2. Train (Amtrak)

    cheapest
    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    6h 38m
    $34–115

  3. Bus (Flixbus)

    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus N2521 / ...
    8h 11m
    $39–70

  4. Drive 306.8 mi

    1. Drive from Northbrook to St. Louiscar car 306.8 mi
    5h 10m
    $56–81

  5. Train, subway to Chicago Midway International Airport, fly

    1. Take the train from Northbrook to Chicago Union Stationtrain train
    2. Take the subway from LaSalle/Van Buren to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    4h 45m
    $109–763

  6. Train to General Mitchell International Airport, fly

    1. Take the train from Glenview Amtrak Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    5h 52m
    $169–1,077

Northbrook to St. Louis by train (Amtrak)

Calendar38Weekly Trains
Duration6h 38mAverage Duration
Ticket$34Cheapest Price
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Questions & Answers

What companies run services between Northbrook, Cook County, IL, USA and St. Louis, MO, USA?

Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $30–110 and the journey takes 4h 46m. Alternatively, Flixbus USA operates a bus from Chicago Bus Station to St Louis Bus Station 3 times a day. Tickets cost $35–65 and the journey takes 6h 10m.

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