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How to get fromNiagara Falls to Iowaby bus, plane, train, bus (Greyhound) or car

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There are 8 ways to get from Niagara Falls to Iowa by bus, plane, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Des Moines

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Des Moines (DSM)plane plane BUF - DSM
    6h 39m
    $273–1,401

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    21h 45m
    $112–258

  3. Train, bus

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    20h 7m
    $136–397

  4. Drive 835.3 mi

    1. Drive from Niagara Falls to Des Moinescar car 835.3 mi
    13h 56m
    $153–221

  5. Bus, fly to Omaha

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Omaha (OMA)plane plane BUF - OMA
    6h 47m
    $261–1,310

  6. Bus, fly to Waterloo Municipal Airport

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Waterloo Municipal Airport (ALO)plane plane BUF - ALO
    6h 34m
    $143–751

  7. Bus, fly to Quad City International Airport

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Quad City International Airport (MLI)plane plane BUF - MLI
    8h 14m
    $118–732

  8. Bus, fly to The Eastern Iowa Airport

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to The Eastern Iowa Airport (CID)plane plane BUF - CID
    3. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    9h 21m

Buffalo Niagara International Airport (BUF) to Des Moines (DSM) flights

Calendar77Weekly Planes
Duration6h 32mAverage Duration
Ticket$250Cheapest Price
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Questions & Answers

What companies run services between Niagara Falls, NY, USA and Iowa, USA?

You can take a bus from Pine Avenue & Main Street to Des Moines via Ellicott Street & MTC Static, Buffalo, Cleveland Bus Station, Chicago Bus Station, and Des Moines in around 21h 45m.

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