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How to get fromNiagara Falls to IowaBy bus, plane, train, bus (Greyhound), or car

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There are 8 ways to get from Niagara Falls to Iowa by bus, plane, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Des Moines

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Des Moines (DSM)plane plane BUF - DSM
    6h 6m
    $251–1,328

  2. Bus, fly to Quad City International Airport

    cheapest
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Quad City International Airport (MLI)plane plane BUF - MLI
    7h 25m
    $101–609

  3. Train, bus

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    20h 3m
    $211–518

  4. Bus (Greyhound)

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    21h 31m
    $145–298

  5. Drive 835.3 mi

    1. Drive from Niagara Falls to Des Moinescar car 835.3 mi
    13h 56m
    $153–221

  6. Bus, fly to Omaha

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Omaha (OMA)plane plane BUF - OMA
    6h 5m
    $269–1,337

  7. Bus, fly to Waterloo Municipal Airport

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Waterloo Municipal Airport (ALO)plane plane BUF - ALO
    6h 49m
    $131–628

  8. Train, bus via Bloomington

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bloomington-Normaltrain train
    4. Take the bus from Bloomington-Normal to Des Moinesbus bus
    22h 57m
    $236–573

Buffalo Niagara International Airport (BUF) to Des Moines (DSM) flights

Calendar99Weekly Planes
Duration5h 39mAverage Duration
Ticket$230Cheapest Price
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Questions & Answers

What companies run services between Niagara Falls, NY, USA and Iowa, USA?

You can take a bus from Pine Avenue & Main Street to Des Moines via Ellicott Street & MTC Static, Buffalo, Cleveland Bus Station, Chicago Bus Station, and Des Moines in around 21h 31m.

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