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How to get fromNiagara Falls to Frederickby bus, plane, bus (Flixbus, Greyhound), train, car, subway, bus (Greyhound), or train (Amtrak)

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There are 9 ways to get from Niagara Falls to Frederick by bus, plane, bus (Flixbus, Greyhound), train, car, subway, bus (Greyhound), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Baltimore-Washington International Airport

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Baltimore-Washington International Airport (BWI)plane plane BUF - BWI
    3. Take the bus from Baltimore to Frederickbus bus
    5h 20m
    $130–517

  2. Drive  325.8 mi

    cheapest
    1. Drive from Niagara Falls to Frederickcar car 325.8 mi
    7h 39m
    $60–86

  3. Bus via Erie

    1. Take the bus from Buffalo to Eriebus bus
    2. Take the bus from Erie to Pittsburgh Intermodal Stationbus bus
    3. Take the bus from Pittsburgh Intermodal Station to Frederick Bus Stationbus bus
    12h 47m
    $75–121

  4. Train, bus (Amtrak)

    1. Take the train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshalltrain train
    3. Take the bus from BWI Amtrak Station to Frederick Transit Centerbus bus Bwi
    14h 26m

  5. Bus, fly to Ronald Reagan Washington National Airport

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Ronald Reagan Washington National Airport (DCA)plane plane BUF - DCA
    3. Take the bus from SHADY GROVE & station to Frederick Marc Stationbus bus
    6h 1m
    $91–566

  6. Bus, fly to Washington Dulles International Airport, subway

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Washington Dulles International Airport (IAD)plane plane BUF - IAD
    3. Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platformsubway subway
    4. Take the bus from SHADY GROVE & station to Frederick Marc Stationbus bus
    6h 37m
    $71–425

  7. Bus

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the bus from Pittsburgh Intermodal Station to Frederick Bus Stationbus bus Greyhound US0430 / ...
    14h 2m
    $87–277

  8. Train

    1. Take the train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to FREDERICK MARC wbtrain train
    14h 52m
    $379–596

  9. Bus, train

    1. Take the bus from Niagara Falls USA to Ithacabus bus
    2. Take the bus from Ithaca to Washington Union Stationbus bus
    3. Take the train from Washington Union Station to FREDERICK MARC wbtrain train
    18h 11m
    $112–185

Niagara Falls to Frederick by bus

Calendar7Weekly Buses
Duration12h 47mAverage Duration
Ticket$75Cheapest Price
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Comparing Your Travel Options

Map of how to get from Niagara Falls to Frederick.ExpandLaunch map view
  • Distance: 362.5 mi
  • Duration: 5h 20m

What companies run services between Niagara Falls, NY, USA and Frederick, MD, USA?

You can take a bus from Pine Avenue & Main Street to Frederick Bus Station via Ellicott Street & MTC Static, Buffalo, Erie, and Pittsburgh Intermodal Station in around 12h 47m. Alternatively, you can take a train from Niagara Falls Amtrak Station to FREDERICK MARC wb via Ny Moynihan Train Hall At Penn Station and Washington Union Station in around 14h 52m.

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