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How to get fromNiagara Falls to Florida Keysby bus, plane, train, car or shuttle

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There are 7 ways to get from Niagara Falls to Florida Keys by bus, plane, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Buffalo Niagara International Airport, fly to Key West International Airport

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)plane plane BUF - EYW
    10h 28m
    $304–1,389

  2. Bus, train

    cheapest
    1. Take the bus from Buffalo to Pittsburghbus bus
    2. Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    2d 5h
    $249–630

  3. Bus, train via Newark

    1. Take the bus from Niagara Falls USA to Newark Penn Stationbus bus
    2. Take the train from Newark Penn Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    43h 44m
    $263–604

  4. Drive 1,541 mi

    1. Drive from Niagara Falls to Florida Keyscar car 1,541 mi
    26h 34m
    $282–407

  5. Bus to Buffalo Niagara International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane BUF - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    11h 5m
    $289–874

  6. Train to Toronto Pearson International Airport, fly to Key West International Airport

    1. Take the train from Canadian Border to Torontotrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Key West International Airport (EYW)plane plane YYZ - EYW
    12h 34m
    $329–567

  7. Train, bus

    1. Take the train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    44h 45m
    $275–655

Niagara Falls to Florida Keys by bus, train, taxi, and foot

Calendar7Weekly Services
Duration43h 44mAverage Duration
Ticket$263Cheapest Price
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Questions & Answers

What companies run services between Niagara Falls, NY, USA and Florida Keys, FL, USA?

There is no direct connection from Niagara Falls to Florida Keys. However, you can take the bus to Buffalo Niagara International Airport, walk to Buffalo Niagara International Airport (BUF) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take a bus from Niagara Falls USA to Florida Keys via Newark, Penn Station, Newark Penn Station, Miami Amtrak Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 43h 44m.

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