Rome2Rio

How to get fromNiagara Falls to Chicago Loopby bus, plane, train (Amtrak), bus (Greyhound), car, train or bus (Flixbus)

Find Transport to Chicago Loop

See all options

There are 8 ways to get from Niagara Falls to Chicago Loop by bus, plane, train (Amtrak), bus (Greyhound), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Buffalo Niagara International Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    4h 44m
    $83–545

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus Greyhound US0170
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    14h 20m
    $60–140

  3. Train

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train Maple Leaf / ...
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    12h 19m
    $78–286

  4. Drive 521.4 mi

    1. Drive from Niagara Falls to Chicago Loopcar car 521.4 mi
    8h 44m
    $96–138

  5. Bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    4h 40m
    $108–785

  6. Bus to Rochester, fly to Chicago O'Hare International Airport

    1. Take the bus from Niagara Falls, NY to Rochester, NYbus bus
    2. Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)plane plane ROC - ORD
    6h 3m
    $132–551

  7. Train to Toronto Pearson International Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Canadian Border to Torontotrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Chicago O'Hare International Airport (ORD)plane plane YYZ - ORD
    7h 11m
    $223–532

  8. Bus via Detroit

    1. Take the bus from Niagara Falls, ON to Toronto Union Stationbus bus
    2. Take the bus from Toronto to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Chicagobus bus
    18h 35m
    $79–234

Niagara Falls to Chicago Loop by train

Calendar14Weekly Trains
Duration12h 19mAverage Duration
Ticket$78Cheapest Price
See schedules

Questions & Answers

What companies run services between Niagara Falls, NY, USA and Chicago Loop, IL, USA?

You can take a train from Niagara Falls Amtrak Station to Chicago Union Station via Buffalo Depew Station in around 12h 19m. Alternatively, you can take a bus from Pine Avenue & Main Street to Washington & Lasalle via Ellicott Street & MTC Static, Buffalo, Cleveland Bus Station, Chicago Bus Station, and Jefferson & Harrison in around 14h 20m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Niagara Falls

Trips to Chicago Loop

Popular routes