Rome2Rio

How to get fromNiagara Falls to Chicago, ILby bus, plane, train (Amtrak), bus (Greyhound), car, train or bus (Flixbus)

Find Transport to Chicago, IL

See all options

There are 8 ways to get from Niagara Falls to Chicago, IL by bus, plane, train (Amtrak), bus (Greyhound), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    4h 32m
    $142–853

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus Greyhound US0170
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    14h 31m
    $62–142

  3. Train

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train Maple Leaf / ...
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    12h 28m
    $123–347

  4. Drive 521.1 mi

    1. Drive from Niagara Falls to Chicago, ILcar car 521.1 mi
    8h 44m
    $96–138

  5. Bus to Buffalo Niagara International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    4h 56m
    $92–503

  6. Bus to Rochester, fly to Chicago Midway International Airport

    1. Take the bus from Niagara Falls, NY to Rochester, NYbus bus
    2. Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)plane plane ROC - MDW
    5h 47m
    $122–711

  7. Train to Toronto Pearson International Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Niagara Falls to Toronto Union Stationtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Chicago O'Hare International Airport (ORD)plane plane YYZ - ORD
    7h 30m
    $212–587

  8. Bus via Detroit

    1. Take the bus from Niagara Falls, ON to Toronto Union Stationbus bus
    2. Take the bus from Toronto to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Chicagobus bus
    19h 41m
    $82–181

Niagara Falls to Chicago, IL by train and foot

Calendar14Weekly Services
Duration12h 28mAverage Duration
Ticket$123Cheapest Price
See schedules

Questions & Answers

What companies run services between Niagara Falls, NY, USA and Chicago, IL, USA?

You can take a train from Niagara Falls Amtrak Station to Chicago, IL via Buffalo Depew Station and Chicago Union Station in around 12h 28m. Alternatively, you can take a bus from Pine Avenue & Main Street to Chicago Bus Station via Ellicott Street & MTC Static, Buffalo, and Cleveland Bus Station in around 14h 31m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Niagara Falls

Trips to Chicago, IL

Popular routes