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There are 9 ways to get from Niagara Falls to Chicago by bus, plane, train, night bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Line 40 bus to Buffalo, fly to Chicago Midway  •  4 h 58 min

  1. Take the line 40 bus from Rainbow Blvd & 1st St to Ellicott St & MTC
  2. Fly from Buffalo (BUF) to Chicago Midway (MDW) BUF - MDW

$136 - $408

Cheapest option

Bus  •  13 h 50 min

  1. Take the bus from Niagara Falls, ON to Toronto, ON 4 stops / ...
  2. Take the bus from Toronto, ON to Chicago, IL 5515 / ...

$58 - $153

7 alternative options

Line 40 bus to Buffalo, fly to Chicago O'Hare  •  5 h 21 min

  1. Take the line 40 bus from Rainbow Blvd & 1st St to Ellicott St & MTC
  2. Fly from Buffalo (BUF) to Chicago O'Hare (ORD) BUF - ORD

$126 - $379

Train to Billy Bishop Toronto City, fly to Chicago Midway  •  6 h 44 min

  1. Take the train from Niagara Falls to Toronto
  2. Fly from Billy Bishop Toronto City (YTZ) to Chicago Midway (MDW) YTZ - MDW

$147 - $450

Train to Rochester, fly to Chicago O'Hare  •  6 h 31 min

  1. Take the train from Niagara Falls Amtrak Station to Rochester Amtrak Station
  2. Fly from Rochester (ROC) to Chicago O'Hare (ORD) ROC - ORD

$172 - $418

Train to Toronto, fly to Chicago O'Hare  •  7 h 11 min

  1. Take the train from Niagara Falls to Toronto
  2. Fly from Toronto (YYZ) to Chicago O'Hare (ORD) YYZ - ORD

$148 - $448

Train  •  12 h 22 min

  1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Station Maple Leaf / ...
  2. Take the train from Buffalo Depew Station to Chicago Union Station Lake Shore Limited

$97 - $260

Bus, night bus  •  15 h 40 min

  1. Take the bus from Niagara Falls, ON to Toronto, ON 4 stops / ...
  2. Take the night bus from Toronto, On to Chicago Amtrak, Il 5531

$63 - $163

Drive  •  8 h 57 min

  1. Drive from Niagara Falls to Chicago 528.7 miles

$50 - $75

Questions & Answers

The cheapest way to get from Niagara Falls to Chicago is to drive which costs $50 - $75 and takes 8 h 57 min.

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The quickest way to get from Niagara Falls to Chicago is to line 40 bus and fly which costs $130 - $410 and takes 4 h 58 min.

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No, there is no direct bus from Niagara Falls to Chicago. However, there are services departing from Niagara Falls, ON and arriving at Chicago, IL via Toronto, ON. The journey, including transfers, takes approximately 13 h 50 min.

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No, there is no direct train from Niagara Falls station to Chicago station. However, there are services departing from Niagara Falls Amtrak Station and arriving at Chicago Union Station via Buffalo Depew Station. The journey, including transfers, takes approximately 12 h 22 min.

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The distance between Niagara Falls and Chicago is 447 miles. The road distance is 528.7 miles.

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The best way to get from Niagara Falls to Chicago without a car is to train which takes 12 h 22 min and costs $95 - $260.

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It takes approximately 4 h 58 min to get from Niagara Falls to Chicago, including transfers.

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Niagara Falls to Chicago bus services, operated by Megabus Canada, depart from Niagara Falls, ON station.

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Niagara Falls to Chicago train services, operated by Amtrak, arrive at Niagara Falls Amtrak Station.

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The best way to get from Niagara Falls to Chicago is to train which takes 12 h 22 min and costs $95 - $260. Alternatively, you can bus, which costs $55 - $160 and takes 13 h 50 min.

Mode details

Map of how to get from Niagara Falls to Chicago.
Launch map view
  • Distance: 447.1 miles
  • Duration: 4 h 58 min

What companies run services between Niagara Falls, NY, USA and Chicago, IL, USA?

You can take a train from Niagara Falls to Chicago via Buffalo Depew Station in around 12 h 22 min. Alternatively, you can take a bus from Niagara Falls to Chicago via Toronto, ON in around 13 h 50 min.

Airlines
Air Canada
Website
aircanada.com
Flights from Buffalo to Chicago O'Hare
Ave. Duration
2 h 2 min
When
Every day
Estimated price
$140 - $750
Flights from Rochester to Chicago O'Hare
Ave. Duration
2 h 4 min
When
Every day
Estimated price
$180 - $700
Flights from Toronto to Chicago O'Hare
Ave. Duration
1 h 56 min
When
Every day
Estimated price
$140 - $700
United Airlines
Website
united.com
Flights from Buffalo to Chicago O'Hare
Ave. Duration
2 h 2 min
When
Every day
Estimated price
$140 - $750
Flights from Buffalo to Chicago O'Hare via Washington Dulles
Ave. Duration
4 h 23 min
When
Every day
Estimated price
$140 - $750
Flights from Rochester to Chicago O'Hare
Ave. Duration
2 h 4 min
When
Every day
Estimated price
$180 - $700
Flights from Toronto to Chicago O'Hare
Ave. Duration
2 h
When
Every day
Estimated price
$150 - $700
American Airlines
Website
aa.com
Flights from Buffalo to Chicago O'Hare
Ave. Duration
2 h 11 min
When
Every day
Estimated price
$120 - $650
Flights from Rochester to Chicago O'Hare
Ave. Duration
2 h 10 min
When
Every day
Estimated price
$160 - $700
Flights from Toronto to Chicago O'Hare
Ave. Duration
2 h 6 min
When
Every day
Estimated price
$130 - $800
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Chicago Midway
Ave. Duration
1 h 48 min
When
Every day
Estimated price
$160 - $750
Flights from Buffalo to Chicago Midway via Baltimore
Ave. Duration
4 h 7 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $750
Porter Airlines
Website
flyporter.com
Flights from Billy Bishop Toronto City to Chicago Midway
Ave. Duration
1 h 50 min
When
Every day
Estimated price
$120 - $700
Delta
Website
delta.com
Flights from Buffalo to Chicago Midway via Detroit
Ave. Duration
3 h 44 min
When
Monday to Friday
Estimated price
$130 - $800
Flights from Buffalo to Chicago O'Hare via Detroit
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$130 - $800
Flights from Toronto to Chicago O'Hare via Detroit
Ave. Duration
3 h 43 min
When
Monday to Saturday
Estimated price
$170 - $1,000
Train operators
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Niagara Falls to Toronto
Ave. Duration
1 h 56 min
Frequency
Once daily
Estimated price
$40 - $85
Website
viarail.ca
Escape
$20 - $45
Economy
$40 - $60
EconomyPlus
$60 - $85
Business
$60 - $85
Train from Niagara Falls Station to Rochester
Ave. Duration
1 h 46 min
Frequency
Once daily
Estimated price
$40 - $90
Website
viarail.ca
Escape
$22 - $45
Economy
$40 - $60
EconomyPlus
$60 - $90
Business
$60 - $90
Train from Niagara Falls Station to Buffalo
Ave. Duration
52 min
Frequency
Once daily
Estimated price
$35 - $75
Website
viarail.ca
Escape
$14 - $40
Economy
$35 - $50
EconomyPlus
$50 - $75
Business
$45 - $65
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Niagara Falls Amtrak Station to Rochester Amtrak Station
Ave. Duration
1 h 46 min
Frequency
3 times a day
Estimated price
$29 - $65
Website
amtrak.com
Coach Seat
$29 - $45
Flexi Coach Seat
$50 - $75
Business Coach Seat
$45 - $65
Room
$150 - $220
Train from Niagara Falls Amtrak Station to Buffalo Depew Station
Ave. Duration
52 min
Frequency
3 times a day
Estimated price
$22 - $45
Website
amtrak.com
Coach Seat
$22 - $35
Flexi Coach Seat
$35 - $60
Business Coach Seat
$29 - $45
Room
$130 - $190
Train from Buffalo Depew Station to Chicago Union Station
Ave. Duration
10 h 30 min
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$140 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
Bus operators
NFTA
Phone
+1 716-855-7300
Website
metro.nfta.com
Bus from Rainbow Blvd & 1st St to Ellicott St & MTC
Ave. Duration
54 min
Frequency
Every 10 minutes
Estimated price
$2
Schedules at
metro.nfta.com
Megabus Canada
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Niagara Falls, ON to Toronto, ON - 610 Bay Street
Ave. Duration
2 h
Frequency
5 times a day
Estimated price
$13 - $35
Website
Greyhound.ca
Advanced Purchase
$13 - $19
Online Fare
$14 - $29
Standard Fare
$23 - $35
Refundable
$26 - $40
Bus from Toronto, ON to Chicago, IL
Ave. Duration
10 h 45 min
Frequency
4 times a day
Estimated price
$45 - $120
Website
Greyhound.ca
Advanced Purchase
$45 - $70
Online Fare
$60 - $90
Standard Fare
$75 - $120
Refundable
$85 - $130
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Niagara Falls, On to Toronto, On
Ave. Duration
1 h 50 min
Frequency
3 times a day
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Night bus from Toronto, On to Chicago Amtrak, Il
Ave. Duration
12 h 35 min
Frequency
Once daily
Estimated price
$50 - $130
Website
greyhound.com
Economy
$50 - $85
Flexible
$100 - $130

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Buffalo Airport to Chicago Midway Airport is the direct flight which takes 1 h 45 min.

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Niagara Falls to Chicago bus services, operated by Greyhound Canada, arrive at Chicago, IL station.

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Chicago is 1 h behind Niagara Falls. It is currently 3:35 PM in Niagara Falls and 2:35 PM in Chicago.

Niagara Falls to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.

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Yes, the driving distance between Niagara Falls to Chicago is 529 miles. It takes approximately 8 h 57 min to drive from Niagara Falls to Chicago.

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Delta and Southwest Airlines offer flights from Buffalo Airport to Chicago Midway Airport.

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Book your Niagara Falls to Chicago train tickets online with Rome2rio.

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Book your Niagara Falls to Chicago bus tickets online with Busbud and Busbud.

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There are 704+ hotels available in Chicago. Prices start at $82 USD per night.

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