There are 7 ways to get from Niagara Falls to Chicago by bus, plane, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Line 40 bus to Buffalo, fly to Chicago O'Hare  •  4 h 43 min

  1. Take the line 40 bus from Rainbow Blvd & 1st St to Ellicott St & MTC
  2. Fly from Buffalo (BUF) to Chicago O'Hare (ORD) BUF - ORD

$132 - $394

Cheapest option

Bus Greyhound Canada  •  13 h 30 min

  1. Take the bus from Niagara Falls, ON to Toronto, ON 4 stops / ...
  2. Take the bus from Toronto, ON to Chicago, IL 5515 / ...

$59 - $129

5 alternative options

Line 40 bus to Buffalo, fly to Chicago Midway  •  4 h 30 min

  1. Take the line 40 bus from Rainbow Blvd & 1st St to Ellicott St & MTC
  2. Fly from Buffalo (BUF) to Chicago Midway (MDW) BUF - MDW

$142 - $423

Train to Rochester, fly to Chicago O'Hare  •  6 h 18 min

  1. Take the train from Niagara Falls Station to Rochester
  2. Fly from Rochester (ROC) to Chicago O'Hare (ORD) ROC - ORD

$170 - $434

Train  •  12 h 23 min

  1. Take the train from Niagara Falls Station to Buffalo VIA Rail / ...
  2. Take the train from Buffalo Depew Station Amtrak to Chicago Union Station Amtrak Lake Shore Limited

$96 - $277

Bus Greyhound USA  •  14 h 25 min

  1. Take the bus from Niagara Falls, ON to Toronto, ON 4 stops / ...
  2. Take the bus from Toronto, On to Chicago, Il 5515

$64 - $159

Drive  •  8 h 57 min

  1. Drive from Niagara Falls to Chicago 528.7 miles

$50 - $75

Questions & Answers

The cheapest way to get from Niagara Falls to Chicago is to drive which costs $50 - $75 and takes 8 h 57 min.

More details

The quickest way to get from Niagara Falls to Chicago is to line 40 bus and fly which takes 4 h 30 min and costs $140 - $430.

More details

The distance between Niagara Falls and Chicago is 715 km. The road distance is 846 km.

Get driving directions

It takes approximately 4 h 43 min to get from Niagara Falls to Chicago, including transfers.

More details

No, there is no direct bus from Niagara Falls to Chicago. However, there are services departing from Niagara Falls, ON and arriving at Chicago, IL via Toronto, ON. The journey, including transfers, takes approximately 13 h 30 min.

More details

No, there is no direct train from Niagara Falls to Chicago. However, there are services departing from Niagara Falls Station and arriving at Chicago Union Station Amtrak via Buffalo Depew Station Amtrak. The journey, including transfers, takes approximately 12 h 23 min.

More details

What companies run services between Niagara Falls, NY, USA and Chicago, IL, USA?

You can take a train from Niagara Falls to Chicago via Buffalo and Buffalo Depew Station Amtrak in around 12 h 23 min. Alternatively, you can take a bus from Niagara Falls to Chicago via Toronto, ON in around 13 h 30 min.

Airlines
United Airlines
Website
united.com
Flights from Buffalo to Chicago O'Hare
Ave. Duration
1 h 47 min
When
Every day
Estimated price
$140 - $750
Flights from Buffalo to Chicago O'Hare via Washington Dulles
Ave. Duration
4 h 9 min
When
Every day
Estimated price
$140 - $750
Flights from Rochester to Chicago O'Hare
Ave. Duration
1 h 51 min
When
Every day
Estimated price
$180 - $700
Air Canada
Website
aircanada.com
Flights from Buffalo to Chicago O'Hare
Ave. Duration
1 h 47 min
When
Every day
Estimated price
$140 - $750
Flights from Rochester to Chicago O'Hare
Ave. Duration
1 h 51 min
When
Every day
Estimated price
$180 - $700
Flights from Rochester to Chicago O'Hare via Toronto
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$140 - $600
American Airlines
Website
aa.com
Flights from Buffalo to Chicago O'Hare
Ave. Duration
1 h 50 min
When
Every day
Estimated price
$120 - $650
Flights from Rochester to Chicago O'Hare
Ave. Duration
1 h 59 min
When
Every day
Estimated price
$160 - $700
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Chicago Midway
Ave. Duration
1 h 38 min
When
Every day
Estimated price
$160 - $750
Delta
Website
delta.com
Flights from Buffalo to Chicago O'Hare via Detroit
Ave. Duration
3 h 39 min
When
Every day
Estimated price
$130 - $800
Flights from Buffalo to Chicago Midway via Detroit
Ave. Duration
3 h 33 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $800
Flights from Rochester to Chicago O'Hare via Detroit
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$160 - $800
Train operators
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Niagara Falls Station to Rochester
Ave. Duration
1 h 46 min
Frequency
Every 3 hours
Estimated price
$27 - $80
Website
viarail.ca
Escape
$27 - $40
Economy
$35 - $50
Economy Plus
$55 - $80
Business
$50 - $75
Business Plus/Sleeper
$90 - $130
Train from Niagara Falls Station to Buffalo
Ave. Duration
52 min
Frequency
Every 3 hours
Estimated price
$21 - $60
Website
viarail.ca
Escape
$21 - $30
Economy
$24 - $35
Economy Plus
$40 - $60
Business
$30 - $50
Business Plus/Sleeper
$60 - $90
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Niagara Falls Amtrak to Rochester Amtrak
Ave. Duration
1 h 42 min
Frequency
4 times a day
Estimated price
$29 - $65
Website
amtrak.com
Coach Seat
$29 - $45
Flexi Coach Seat
$50 - $75
Business Coach Seat
$45 - $65
Room
$150 - $220
Train from Niagara Falls Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
48 min
Frequency
4 times a day
Estimated price
$22 - $45
Website
amtrak.com
Coach Seat
$22 - $35
Flexi Coach Seat
$35 - $60
Business Coach Seat
$29 - $45
Room
$130 - $190
Train from Buffalo Depew Station Amtrak to Chicago Union Station Amtrak
Ave. Duration
10 h 31 min
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$140 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
Bus operators
Niagara Frontier
Website
metro.nfta.com
Bus from Rainbow Blvd & 1st St to Ellicott St & MTC
Ave. Duration
53 min
Frequency
Every 15 minutes
Estimated price
$2
Schedules at
metro.nfta.com
Megabus CA
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Niagara Falls, On to Toronto, On
Ave. Duration
1 h 50 min
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Toronto, On to Chicago, Il
Ave. Duration
11 h 45 min
Frequency
Hourly
Estimated price
$50 - $140
Website
greyhound.com
Economy
$50 - $85
Flexible
$100 - $140
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Toronto, ON to Chicago, IL
Ave. Duration
10 h 45 min
Frequency
4 times a day
Estimated price
$45 - $110
Website
Greyhound.ca
Advanced Purchase
$45 - $70
Online Fare
$60 - $90
Standard Fare
$75 - $110
Refundable
$85 - $130

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