Peter Pan Bus Lines operates a bus from New York to Waterbury every 4 hours. Tickets cost $12 - $24 and the journey takes 2 h 30 min. Alternatively, Amtrak Acela Express operates a train from New York to Waterbury hourly. Tickets cost $70 - $190 and the journey takes 1 h 37 min. 2 other operators also service this route.
From New York, NY - Port Authority Bus Terminal bus to Waterbury, CT - Travel Center. 2 h 30 min $12. From New York Penn Station train to Union Ave and Union Station, bus to Church St and Chapel St, then bus to State St and W Main St. 3 h 15 min $169. From Grand Central train to Bridgeport then train to Waterbury. 3 h 23 min $27. From New York drive to Waterbury. 1 h 42 min $11.