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There are 10 ways to get from New York to Mayo Clinic by plane, bus, ferry, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Newark to Rochester  •  7h 22m

  1. Fly from Newark (EWR) to Rochester (RST) EWR - RST

$156 - $216

Cheapest option

Fly New York La Guardia to Minneapolis, bus  •  7h 6m

  1. Fly from New York La Guardia (LGA) to Minneapolis (MSP) LGA - MSP
  2. Take the bus from Minneapolis-St Paul Airport, MN to Rochester, MN

$114 - $290

8 alternative options

Fly New York La Guardia to Rochester  •  7h 42m

  1. Fly from New York La Guardia (LGA) to Rochester (RST) LGA - RST

$173 - $332

Fly New York JFK to Rochester  •  7h 50m

  1. Fly from New York JFK (JFK) to Rochester (RST) JFK - RST

$115 - $632

Fly Newark to Minneapolis, bus  •  6h 51m

  1. Fly from Newark (EWR) to Minneapolis (MSP) EWR - MSP
  2. Take the bus from Minneapolis-St Paul Airport, MN to Rochester, MN

$122 - $294

Fly New York JFK to Minneapolis, bus  •  7h 9m

  1. Fly from New York JFK (JFK) to Minneapolis (MSP) JFK - MSP
  2. Take the bus from Minneapolis-St Paul Airport, MN to Rochester, MN

$181 - $440

Bus, ferry  •  26h 42m

  1. Take the bus from New York, NY - 3 Allen St to Chicago Nyc
  2. Take the ferry from Chinatown to Ogilvie/Union
  3. Take the bus from Chicago Union Station to Madison Amtrak Bus Stop
  4. Take the bus from Madison to Rochester, MN 966

$120 - $198

Train, bus  •  27h 34m

  1. Take the train from New York Moynihan Train Hall to Chicago Union Station
  2. Take the train from Chicago Union Station to Winona Amtrak Station
  3. Take the bus from Winona Amtrak Station to Rochester, MN

$160 - $226

Train, bus via Madison  •  29h 17m

  1. Take the train from New York Moynihan Train Hall to Chicago Union Station
  2. Take the bus from Chicago Union Station to Madison Amtrak Bus Stop
  3. Take the bus from Madison to Rochester, MN 966

$160 - $228

Drive  •  18h 48m

  1. Drive from New York to Mayo Clinic 1144 miles

$110 - $170

New York to Mayo Clinic by bus, walk and ferry

The journey time between New York and Mayo Clinic is around 42h 30m and covers a distance of around 1173 miles. The fastest journey normally takes 42h 30m. Operated by Wanda Coach, Chicago Water Taxi, Amtrak and others, the New York to Mayo Clinic service departs from New York, NY - 3 Allen St and arrives in Mayo Clinic. Typically only one service runs weekly, although weekend and holiday schedules can vary so check in advance.

Route overview

Average journey time:
42h 30m
Fastest journey time:
42h 30m
Journey distance:
1173 miles
Services per week:
1
Cheapest price:
$120
Carbon emissions:
233 kg CO2

First and last service

First service departs at:
21:30
Last service departs at:
21:30

The schedules shown below are for the next available departures.

New York to Mayo Clinic bus, walk and ferry schedules

New York → Mayo Clinic
Fully open

Travel safe during COVID-19

Rules to follow in United States

2m

Recommended

Recommended

Travel within United States

Domestic border crossings may be subject to approval, testing and quarantine

COVID-19 help in United States

If you need help, visit the national COVID-19 website or call the COVID-19 Helpline 800-232-4636

Frequently Asked Questions


Yes, travel within United States is currently allowed.

Explore travel options

Domestic travel is not restricted, but some conditions may apply

  • Face masks are recommended
  • There is a social distancing requirement of 2 metres
  • Domestic border crossings may be subject to approval, testing and quarantine

Explore travel options

The national COVID-19 helpline number in Mayo Clinic is 800-232-4636.

Wearing a face mask on public transport in Mayo Clinic is recommended.

The social distance requirement in Mayo Clinic is 2 metres.

Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 800-232-4636.

Last updated: 22 Jul 2021
Exceptions may apply, for full details: Centers for Disease control and prevention (CDC).

We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.

Questions & Answers

The most affordable way to get from New York to Mayo Clinic is to drive, which costs $110 - $170 and takes 18h 48m.

More details

The quickest way to get from New York to Mayo Clinic is to fly and bus which costs $120 - $300 and takes 6h 51m.

More details

The distance between New York and Mayo Clinic is 973 miles. The road distance is 1144 miles.

Get driving directions

The best way to get from New York to Mayo Clinic without a car is to bus and ferry which takes 26h 42m and costs $120 - $200.

More details

It takes approximately 7h 22m to get from New York to Mayo Clinic, including transfers.

More details

There is no direct flight from Newark Airport to Rochester Airport. The quickest flight takes 4h 40m and has one stopover.

Search flights

Yes, the driving distance between New York to Mayo Clinic is 1144 miles. It takes approximately 18h 48m to drive from New York to Mayo Clinic.

Get driving directions

American Airlines, United Airlines and Delta offer flights from Newark Airport to Rochester Airport.

Search flights

There are 56+ hotels available in Mayo Clinic. Prices start at $100 USD per night.

More details

Map of how to get from New York to Mayo Clinic.
Launch map view
  • Distance: 973.1 miles
  • Duration: 7h 22m

What companies run services between New York, NY, USA and Mayo Clinic, MN, USA?

United Airlines, American Airlines and Delta fly from New York to Mayo Clinic hourly.

Airlines
Delta
Website
delta.com
Flights from Newark to Rochester via Minneapolis
Ave. Duration
5h 38m
When
Every day
Estimated price
$90 - $550
Flights from Newark to Rochester via Atlanta
Ave. Duration
7h 5m
When
Every day
Estimated price
$120 - $650
Flights from Newark to Rochester via Detroit, Minneapolis
Ave. Duration
6h 50m
When
Every day
Estimated price
$90 - $550
Flights from Newark to Rochester via Covington, Minneapolis
Ave. Duration
7h 9m
When
Every day
Estimated price
$100 - $600
Flights from New York La Guardia to Rochester via Minneapolis
Ave. Duration
5h 50m
When
Every day
Estimated price
$100 - $600
Flights from New York La Guardia to Rochester via Atlanta
Ave. Duration
7h 15m
When
Every day
Estimated price
$140 - $700
Flights from New York La Guardia to Rochester via Detroit, Minneapolis
Ave. Duration
7h 16m
When
Every day
Estimated price
$100 - $600
Flights from New York JFK to Rochester via Minneapolis
Ave. Duration
5h 40m
When
Every day
Estimated price
$95 - $600
Flights from New York JFK to Rochester via Atlanta
Ave. Duration
7h 30m
When
Every day
Estimated price
$130 - $700
Flights from New York JFK to Rochester via Detroit, Minneapolis
Ave. Duration
7h 8m
When
Every day
Estimated price
$100 - $600
Flights from New York JFK to Rochester via Chicago O'Hare, Minneapolis
Ave. Duration
8h 27m
When
Every day
Estimated price
$100 - $600
Flights from New York JFK to Rochester via Nashville, Minneapolis
Ave. Duration
8h 9m
When
Every day
Estimated price
$130 - $650
Flights from New York JFK to Rochester via Pittsburgh, Minneapolis
Ave. Duration
8h 17m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$100 - $600
Flights from New York JFK to Rochester via Reagan Washington, Minneapolis
Ave. Duration
8h 43m
When
Every day
Estimated price
$100 - $600
Flights from New York JFK to Rochester via Indianapolis, Minneapolis
Ave. Duration
9h 4m
When
Every day
Estimated price
$110 - $600
Flights from Newark to Minneapolis
Ave. Duration
3h 4m
When
Every day
Estimated price
$60 - $380
Flights from Newark to Minneapolis via Detroit
Ave. Duration
4h 59m
When
Every day
Estimated price
$60 - $390
Flights from Newark to Minneapolis via Covington
Ave. Duration
4h 56m
When
Every day
Estimated price
$70 - $400
Flights from New York La Guardia to Minneapolis
Ave. Duration
3h 9m
When
Every day
Estimated price
$70 - $430
Flights from New York La Guardia to Minneapolis via Pittsburgh
Ave. Duration
4h 42m
When
Every day
Estimated price
$70 - $440
Flights from New York La Guardia to Minneapolis via Grand Rapids
Ave. Duration
4h 49m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$70 - $430
Flights from New York La Guardia to Minneapolis via Columbus
Ave. Duration
5h 4m
When
Every day
Estimated price
$75 - $440
Flights from New York JFK to Minneapolis
Ave. Duration
3h 16m
When
Every day
Estimated price
$65 - $410
Flights from New York JFK to Minneapolis via Pittsburgh
Ave. Duration
4h 57m
When
Every day
Estimated price
$70 - $420
Flights from New York JFK to Minneapolis via Detroit
Ave. Duration
5h 22m
When
Every day
Estimated price
$65 - $410
Flights from New York JFK to Minneapolis via Nashville
Ave. Duration
5h 44m
When
Every day
Estimated price
$90 - $470
Flights from New York JFK to Minneapolis via Chicago O'Hare
Ave. Duration
5h 55m
When
Every day
Estimated price
$70 - $420
Flights from New York JFK to Minneapolis via Raleigh/Durham
Ave. Duration
6h 2m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$90 - $460
United Airlines
Website
united.com
Flights from Newark to Rochester via Chicago O'Hare
Ave. Duration
4h 53m
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $370
Flights from Newark to Rochester via Denver
Ave. Duration
7h 25m
When
Every day
Estimated price
$210 - $370
Flights from Newark to Rochester via Reagan Washington, Chicago O'Hare
Ave. Duration
7h 30m
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $370
Flights from New York La Guardia to Rochester via Chicago O'Hare
Ave. Duration
5h 11m
When
Every day
Estimated price
$220 - $700
Flights from New York La Guardia to Rochester via Denver
Ave. Duration
7h 40m
When
Every day
Estimated price
$220 - $700
Flights from Newark to Minneapolis
Ave. Duration
3h 8m
When
Every day
Estimated price
$220 - $600
Flights from Newark to Minneapolis via Chicago O'Hare
Ave. Duration
4h 49m
When
Every day
Estimated price
$220 - $600
Flights from Newark to Minneapolis via Toronto
Ave. Duration
5h 11m
When
Every day
Estimated price
$120 - $650
Flights from New York La Guardia to Minneapolis via Chicago O'Hare
Ave. Duration
4h 53m
When
Every day
Estimated price
$250 - $700
American Airlines
Website
aa.com
Flights from Newark to Rochester via Chicago O'Hare
Ave. Duration
4h 58m
When
Every day
Estimated price
$210 - $700
Flights from Newark to Rochester via Charlotte, Chicago O'Hare
Ave. Duration
7h 36m
When
Every day
Estimated price
$210 - $700
Flights from New York La Guardia to Rochester via Chicago O'Hare
Ave. Duration
6h 12m
When
Every day
Estimated price
$310 - $700
Flights from New York La Guardia to Rochester via Wilmington, Chicago O'Hare
Ave. Duration
7h 13m
When
Every day
Estimated price
$310 - $700
Flights from New York La Guardia to Rochester via Pittsburgh, Chicago O'Hare
Ave. Duration
7h 22m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $700
Flights from New York La Guardia to Rochester via Reagan Washington, Chicago O'Hare
Ave. Duration
7h 22m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $700
Flights from New York JFK to Rochester via Chicago O'Hare
Ave. Duration
9h 38m
When
Every day
Estimated price
$180 - $650
Flights from New York JFK to Rochester via Reagan Washington, Chicago O'Hare
Ave. Duration
9h 4m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$180 - $650
Flights from New York La Guardia to Minneapolis
Ave. Duration
3h 8m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $600
Flights from New York JFK to Minneapolis
Ave. Duration
3h 8m
When
Every day
Estimated price
$270 - $600
Flights from New York JFK to Minneapolis via Charlotte
Ave. Duration
6h 3m
When
Every day
Estimated price
$220 - $650
Air Canada
Website
aircanada.com
Flights from Newark to Minneapolis via Chicago O'Hare
Ave. Duration
4h 49m
When
Every day
Estimated price
$220 - $600
Flights from Newark to Minneapolis via Toronto
Ave. Duration
5h 11m
When
Every day
Estimated price
$120 - $650
Southwest Airlines
Website
southwest.com
Flights from New York La Guardia to Minneapolis via Chicago Midway
Ave. Duration
4h 42m
When
Saturday and Sunday
Estimated price
$120 - $420
Sun Country Airlines
Website
suncountry.com
Flights from Newark to Minneapolis
Ave. Duration
2h 54m
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$110 - $340
Spirit Airlines
Website
spirit.com
Flights from New York La Guardia to Minneapolis via Detroit
Ave. Duration
5h 9m
When
Tuesday, Thursday and Sunday
Estimated price
$100 - $350
JetBlue Airways
Website
jetblue.com
Flights from New York JFK to Minneapolis
Ave. Duration
3h 8m
When
Every day
Estimated price
$270 - $600
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from New York Moynihan Train Hall to Chicago Union Station
Ave. Duration
19h 10m
Frequency
Once daily
Estimated price
$95 - $140
Schedules at
amtrak.com
Coach Seat
$95 - $140
Premium
$320 - $440
Flexi Coach Seat
$190 - $290
Business Seat
$210 - $300
Train from Chicago Union Station to Winona Amtrak Station
Ave. Duration
5h 26m
Frequency
5 times a day
Estimated price
$45 - $65
Schedules at
amtrak.com
Coach Seat
$45 - $65
Premium
$220 - $310
Flexi Coach Seat
$80 - $120
Business Seat
$80 - $120
Bus operators
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Minneapolis-St Paul Airport, MN to Rochester, MN
Ave. Duration
1h 20m
Frequency
Once daily
Estimated price
$19 - $30
Book at
jeffersonlines.com
Bus from Madison to Rochester, MN
Ave. Duration
4h 45m
Frequency
Once daily
Estimated price
$30 - $60
Book at
jeffersonlines.com
Wanda Coach
Phone
646-630-7186
Email
help@wandacoach.com
Website
wandacoach.com
Bus from New York, NY - 3 Allen St to Chicago
Ave. Duration
15h
Frequency
3 times a week
Estimated price
$50 - $100
Book at
GoTo Bus
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Bus from Chicago Union Station to Madison Amtrak Bus Stop
Ave. Duration
3h 40m
Frequency
Every 2 hours
Schedules at
amtrak.com
Vangalder Bus
Phone
+1 608-752-5407
Email
vangalder@coachusa.com
Bus from Chicago Union Station to Madison, WI-Lake St.
Ave. Duration
3h 35m
Frequency
Every 3 hours
Estimated price
$32
Schedules at
vangalderbus.com
Book at
govangalder.com
Amtrak Thruway

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Thruway
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Bus from Winona Amtrak Station to Rochester, MN
Ave. Duration
55 min
Frequency
3 times a week
Estimated price
$17 - $25
Schedules at
amtrak.com
Ferry operators
Chicago Water Taxi
Phone
312-337-1446
Website
chicagowatertaxi.com
Ferry from Chinatown to Ogilvie/Union
Ave. Duration
20 min
Frequency
Twice daily
Estimated price
$6
Schedules at
chicagowatertaxi.com

Want to know more about travelling around United States

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