Rome2Rio

How to get fromNew York to Defianceby bus (Flixbus, Amtrak), train (Amtrak), car, plane, train, bus (Greyhound, Amtrak), bus, or taxi

Find Transport to Defiance

See all options

There are 11 ways to get from New York to Defiance by bus (Flixbus, Amtrak), train (Amtrak), car, plane, train, bus (Greyhound, Amtrak), bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from New York Midtown to Toledo Bus Stopbus bus FlixBus N2641
    2. Take the bus from Toledo to Bryan Amtrak Stationbus bus Amtrak Thruway Connecting Service
    14h 15m
    $161–240

  2. Drive 596.7 mi

    cheapest
    1. Drive from New York to Defiancecar car 596.7 mi
    10h 26m
    $109–158

  3. Train (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Bryan Amtrak Stationtrain train Lake Shore Limited
    16h 13m
    $291–554

  4. Fly Newark Liberty International Airport to Cleveland-Hopkins International Airport, train

    1. Fly from Newark Liberty International Airport (EWR) to Cleveland-Hopkins International Airport (CLE)plane plane EWR - CLE
    2. Take the train from Cleveland Amtrak to Bryan Amtrak Stationtrain train
    8h 58m
    $383–800

  5. Bus via Port Authority Bus Terminal

    1. Take the bus from Port Authority Bus Terminal to Toledo Bus Stopbus bus Greyhound US0420
    2. Take the bus from Toledo to Bryan Amtrak Stationbus bus Amtrak Thruway Connecting Service
    18h 30m
    $173–285

  6. Fly Newark Liberty International Airport to John Glenn Columbus International Airport, bus, taxi

    1. Fly from Newark Liberty International Airport (EWR) to John Glenn Columbus International Airport (CMH)plane plane EWR - CMH
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Delphosbus bus
    3. Take the taxi from Delphos to Defiancetaxi taxi
    8h 41m
    $275–637

  7. Fly Laguardia Airport to John Glenn Columbus International Airport, bus, taxi

    1. Fly from Laguardia Airport (LGA) to John Glenn Columbus International Airport (CMH)plane plane LGA - CMH
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Delphosbus bus
    3. Take the taxi from Delphos to Defiancetaxi taxi
    8h 53m
    $250–600

  8. Fly Newark Liberty International Airport to Detroit, bus, train

    1. Fly from Newark Liberty International Airport (EWR) to Detroit (DTW)plane plane EWR - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    9h 1m
    $181–459

  9. Fly Laguardia Airport to Detroit, bus, train

    1. Fly from Laguardia Airport (LGA) to Detroit (DTW)plane plane LGA - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    9h 19m
    $161–442

  10. Fly John F. Kennedy International Airport to Detroit, bus, train

    1. Fly from John F. Kennedy International Airport (JFK) to Detroit (DTW)plane plane JFK - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    9h 18m
    $180–550

  11. Fly Westchester County Airport to Detroit, bus, train

    1. Fly from Westchester County Airport (HPN) to Detroit (DTW)plane plane HPN - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    10h 58m
    $209–710

Newark Liberty International Airport (EWR) to Cleveland-Hopkins International Airport (CLE) flights

Calendar62Weekly Planes
Duration2h 45mAverage Duration
Ticket$86Cheapest Price
See schedules

Questions & Answers

Map of how to get from New York to Defiance.ExpandLaunch map view
  • Distance: 727.1 mi
  • Duration: 14h 15m

What companies run services between New York, NY, USA and Defiance, OH, USA?

You can take a bus from New York Midtown to Defiance via Toledo and Bryan Amtrak Station in around 14h 15m. Alternatively, Amtrak operates a train from Ny Moynihan Train Hall At Penn Station to Bryan Amtrak Station once daily. Tickets cost $230–490 and the journey takes 15h 43m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound