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How to get fromNew York to Defianceby plane, bus, taxi, bus (Flixbus, Amtrak), train (Amtrak), car, train, or bus (Greyhound, Amtrak)

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There are 11 ways to get from New York to Defiance by plane, bus, taxi, bus (Flixbus, Amtrak), train (Amtrak), car, train, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Newark Liberty International Airport to John Glenn Columbus International Airport, bus, taxi

    best
    1. Fly from Newark Liberty International Airport (EWR) to John Glenn Columbus International Airport (CMH)plane plane EWR - CMH
    2. Take the bus from Wilson & Ferrell Shell Station - Columbus to Delphosbus bus
    3. Take the taxi from Delphos to Defiancetaxi taxi
    8h 25m
    $295–1,164

  2. Drive  596.7 mi

    cheapest
    1. Drive from New York to Defiancecar car 596.7 mi
    10h 26m
    $109–158

  3. Bus

    1. Take the bus from New York Midtown to Toledo Bus Stopbus bus FlixBus N2641
    2. Take the bus from Toledo to Bryan Amtrak Stationbus bus Amtrak Thruway Connecting Service
    14h 15m

  4. Train (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Bryan Amtrak Stationtrain train Lake Shore Limited
    16h 13m
    $485–730

  5. Fly Newark Liberty International Airport to Cleveland-Hopkins International Airport, train

    1. Fly from Newark Liberty International Airport (EWR) to Cleveland-Hopkins International Airport (CLE)plane plane EWR - CLE
    2. Take the train from Cleveland Amtrak to Bryan Amtrak Stationtrain train
    8h 59m
    $335–1,092

  6. Fly Laguardia Airport to John Glenn Columbus International Airport, bus, taxi

    1. Fly from Laguardia Airport (LGA) to John Glenn Columbus International Airport (CMH)plane plane LGA - CMH
    2. Take the bus from Wilson & Ferrell Shell Station - Columbus to Delphosbus bus
    3. Take the taxi from Delphos to Defiancetaxi taxi
    8h 49m
    $339–696

  7. Fly Newark Liberty International Airport to Detroit, bus, train

    1. Fly from Newark Liberty International Airport (EWR) to Detroit (DTW)plane plane EWR - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    9h 2m

  8. Fly Laguardia Airport to Detroit, bus, train

    1. Fly from Laguardia Airport (LGA) to Detroit (DTW)plane plane LGA - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    9h 22m

  9. Fly John F. Kennedy International Airport to Detroit, bus, train

    1. Fly from John F. Kennedy International Airport (JFK) to Detroit (DTW)plane plane JFK - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    9h 17m

  10. Fly Westchester County Airport to Detroit, bus, train

    1. Fly from Westchester County Airport (HPN) to Detroit (DTW)plane plane HPN - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    10h 57m

  11. Bus via Port Authority Bus Terminal

    1. Take the bus from Port Authority Bus Terminal to Toledo Bus Stopbus bus Greyhound US0420
    2. Take the bus from Toledo to Bryan Amtrak Stationbus bus Amtrak Thruway Connecting Service
    18h 30m

Newark Liberty International Airport (EWR) to John Glenn Columbus International Airport (CMH) flights

Calendar95Weekly Planes
Duration2h 57mAverage Duration
Ticket$86Cheapest Price
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Comparing Your Travel Options

Map of how to get from New York to Defiance.ExpandLaunch map view
  • Distance: 621 mi
  • Duration: 8h 25m

What companies run services between New York, NY, USA and Defiance, OH, USA?

You can take a bus from New York Midtown to Defiance via Toledo and Bryan Amtrak Station in around 14h 15m. Alternatively, Amtrak operates a train from Ny Moynihan Train Hall At Penn Station to Bryan Amtrak Station once daily. Tickets cost $430–700 and the journey takes 15h 43m.

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